Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA B receptors

(2016) Joel Castro et al.   GUT

GABAB receptors inhibit low-voltage activated and high-voltage activated Ca2+ channels in sensory neurons via distinct mechanisms

(2015) Dongyang Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity

(2014) Annemie Deiteren et al.   GUT

Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABABreceptor activation

(2014) Géza Berecki et al.   JOURNAL OF GENERAL PHYSIOLOGY

Influence of Disulfide Connectivity on Structure and Bioactivity of α-Conotoxin TxIA

(2014) Yong Wu et al.   MOLECULES

Discovery of a new subclass of α-conotoxins in the venom of Conus australis

(2014) Eline K.M. Lebbe et al.   TOXICON

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

(2014) Aline Dantas de Araujo et al.   Nature Communications

Linaclotide Inhibits Colonic Nociceptors and Relieves Abdominal Pain via Guanylate Cyclase-C and Extracellular Cyclic Guanosine 3′,5′-Monophosphate

(2013) Joel Castro et al.   GASTROENTEROLOGY

Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor

(2013) Rilei Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modulation of Conotoxin Structure and Function Is Achieved through a Multienzyme Complex in the Venom Glands of Cone Snails

(2012) Helena Safavi-Hemami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain

(2012) I.A. Napier et al.   NEUROPHARMACOLOGY

Embryonic Toxin Expression in the Cone SnailConus victoriae

(2011) Helena Safavi-Hemami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Activity of α-Conotoxin PeIA at Nicotinic Acetylcholine Receptor Subtypes and GABABReceptor-coupled N-type Calcium Channels

(2011) Norelle L. Daly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

(2011) Q. Kaas et al.   NUCLEIC ACIDS RESEARCH

The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

(2010) Richard J. Clark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analgesic α-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in sensory neurons of α9 nicotinic receptor knockout mice

(2010) Brid Callaghan et al.   Channels

α-Conotoxin AuIB Isomers Exhibit Distinct Inhibitory Mechanisms and Differential Sensitivity to Stoichiometry of α3β4 Nicotinic Acetylcholine Receptors

(2010) Anton A. Grishin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain

(2010) Harry Klimis et al.   PAIN

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Conus Venoms - A Rich Source of Peptide-Based Therapeutics

(2008) Tiffany Han et al.   CURRENT PHARMACEUTICAL DESIGN

Analgesic  -Conotoxins Vc1.1 and Rg1A Inhibit N-Type Calcium Channels in Rat Sensory Neurons via GABAB Receptor Activation

(2008) B. Callaghan et al.   JOURNAL OF NEUROSCIENCE

Modulation of pain transmission by G-protein-coupled receptors

(2007) Hui-Lin Pan et al.   PHARMACOLOGY & THERAPEUTICS