Simultaneous voltage and calcium imaging and optogenetic stimulation with high sensitivity and a wide field of view

A genetically encoded Ca2+ indicator based on circularly permutated sea anemone red fluorescent protein eqFP578

(2018) Yi Shen et al.   BMC BIOLOGY

Ultrawidefield microscope for high-speed fluorescence imaging and targeted optogenetic stimulation

(2017) Christopher A. Werley et al.   Biomedical Optics Express

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Pluripotent stem cells in disease modelling and drug discovery

(2016) Yishai Avior et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging

(2016) Graham T. Dempsey et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

(2015) Cedric Bardy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic control of intracellular signaling pathways

(2015) Kai Zhang et al.   TRENDS IN BIOTECHNOLOGY

para-Nitroblebbistatin, the Non-Cytotoxic and Photostable Myosin II Inhibitor

(2014) Miklós Képiró et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Temporal Dynamics of Microbial Rhodopsin Fluorescence Reports Absolute Membrane Voltage

(2014) Jennifer H. Hou et al.   BIOPHYSICAL JOURNAL

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

(2014) Daniel R Hochbaum et al.   NATURE METHODS

Rational design of a high-affinity, fast, red calcium indicator R-CaMP2

(2014) Masatoshi Inoue et al.   NATURE METHODS

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Mechanism of voltage-sensitive fluorescence in a microbial rhodopsin

(2013) D. Maclaurin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated whole-cell patch-clamp electrophysiology of neurons in vivo

(2012) Suhasa B Kodandaramaiah et al.   NATURE METHODS

Reporting from the Field: Genetically Encoded Fluorescent Reporters Uncover Signaling Dynamics in Living Biological Systems

(2011) Sohum Mehta et al.   Annual Review of Biochemistry

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

(2011) HG Laverty et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells

(2011) Robert H. Newman et al.   CHEMICAL REVIEWS

An Expanded Palette of Genetically Encoded Ca2+ Indicators

(2011) Y. Zhao et al.   SCIENCE

Voltage-Gated Calcium Channels

(2011) W. A. Catterall   Cold Spring Harbor Perspectives in Biology

A user's guide to channelrhodopsin variants: features, limitations and future developments

(2010) John Y. Lin   EXPERIMENTAL PHYSIOLOGY

High-resolution simultaneous voltage and Ca2+imaging

(2010) Kaspar E. Vogt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of voltage-gated calcium channels in epilepsy

(2009) Gerald W. Zamponi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience