Pervasive function and evidence for selection across standing genetic variation in S. cerevisiae

DNA fragility in the parallel evolution of pelvic reduction in stickleback fish

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Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change

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Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing

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Genome evolution across 1,011 Saccharomyces cerevisiae isolates

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Catalytic efficiency and thermostability improvement of Suc2 invertase through rational site-directed mutagenesis

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Multiple Modes of Positive Selection Shaping the Patterns of Incomplete Selective Sweeps over African Populations of Drosophila melanogaster

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Rare and low-frequency coding variants alter human adult height

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Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast

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Contrasting evolutionary genome dynamics between domesticated and wild yeasts

(2017) Jia-Xing Yue et al.   NATURE GENETICS

Loci associated with skin pigmentation identified in African populations

(2017) Nicholas G. Crawford et al.   SCIENCE

Parallel evolution of influenza across multiple spatiotemporal scales

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Development of a Comprehensive Genotype-to-Fitness Map of Adaptation-Driving Mutations in Yeast

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Schizophrenia risk from complex variation of complement component 4

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Genetic drift, selection and the evolution of the mutation rate

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Can Population Genetics Adapt to Rapid Evolution?

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Population genomics of yeasts: towards a comprehensive view across a broad evolutionary scale

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The 100-genomes strains, anS. cerevisiaeresource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen

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Detecting balancing selection in genomes: limits and prospects

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Genetic interactions contribute less than additive effects to quantitative trait variation in yeast

(2015) Joshua S. Bloom et al.   Nature Communications

Standing Genetic Variation Drives Repeatable Experimental Evolution in Outcrossing Populations of Saccharomyces cerevisiae

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A High-Definition View of Functional Genetic Variation from Natural Yeast Genomes

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Detecting epistasis in human complex traits

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Global epistasis makes adaptation predictable despite sequence-level stochasticity

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Metabolism in Fungal Pathogenesis

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Detecting Natural Selection in Genomic Data

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The molecular basis of phenotypic variation in yeast

(2013) Justin C Fay   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genome-wide signatures of convergent evolution in echolocating mammals

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Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

(2013) Gregory I. Lang et al.   NATURE

Epistasis and quantitative traits: using model organisms to study gene–gene interactions

(2013) Trudy F. C. Mackay   NATURE REVIEWS GENETICS

Pitfalls of predicting complex traits from SNPs

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SGAtools: one-stop analysis and visualization of array-based genetic interaction screens

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GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

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Evidence for parallel adaptation to climate across the natural range ofArabidopsis thaliana

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Whole Genome, Whole Population Sequencing Reveals That Loss of Signaling Networks Is the Major Adaptive Strategy in a Constant Environment

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Surprisingly diverged populations ofSaccharomyces cerevisiaein natural environments remote from human activity

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Parallel Molecular Evolution in an Herbivore Community

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Mutation Hot Spots in Yeast Caused by Long-Range Clustering of Homopolymeric Sequences

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THE QTN PROGRAM AND THE ALLELES THAT MATTER FOR EVOLUTION: ALL THAT'S GOLD DOES NOT GLITTER

(2011) Matthew V. Rockman   EVOLUTION

Steric hindrance by 2 amino acid residues determines the substrate specificity of isomaltase from Saccharomyces cerevisiae

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Molecular mechanisms of epistasis within and between genes

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Coupled Evolution of Transcription and mRNA Degradation

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Reciprocal Sign Epistasis between Frequently Experimentally Evolved Adaptive Mutations Causes a Rugged Fitness Landscape

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Trait Variation in Yeast Is Defined by Population History

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Characterization of a New Multigene Family Encoding Isomaltases in the YeastSaccharomyces cerevisiae, theIMAFamily

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

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Evidence for widespread adaptive evolution of gene expression in budding yeast

(2010) H. B. Fraser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fungal metabolism in host niches

(2009) Matthias Brock   CURRENT OPINION IN MICROBIOLOGY

Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae

(2009) Joseph Schacherer et al.   NATURE

Population genomics of domestic and wild yeasts

(2009) Gianni Liti et al.   NATURE

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Estimating the Per-Base-Pair Mutation Rate in the Yeast Saccharomyces cerevisiae

(2008) Gregory I. Lang et al.   GENETICS

Molecular characterization of clonal interference during adaptive evolution in asexual populations of Saccharomyces cerevisiae

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A comprehensive strategy enabling high-resolution functional analysis of the yeast genome

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Population genomics of the wild yeast Saccharomyces paradoxus: Quantifying the life cycle

(2008) I. J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA