Metformin exerts antidepressant effects by regulated DNA hydroxymethylation

Plasma brain-derived neurotrophic factor (pBDNF) and executive dysfunctions in patients with major depressive disorder

(2018) Stefanie Wagner et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Brain-Derived Neurotrophic Factor and Major Depressive Disorder: Evidence from Meta-Analyses

(2018) Taro Kishi et al.   Frontiers in Psychiatry

Let-7i inhibition enhances progesterone-induced functional recovery in a mouse model of ischemia

(2018) Trinh Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice

(2018) Ying Cheng et al.   Cell Reports

Metformin: Insights into its anticancer potential with special reference to AMPK dependent and independent pathways

(2017) Shoeb Ikhlas et al.   LIFE SCIENCES

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

(2017) Jian Feng et al.   NEUROPSYCHOPHARMACOLOGY

Metformin – a Future Therapy for Neurodegenerative Diseases

(2017) Magdalena Markowicz-Piasecka et al.   PHARMACEUTICAL RESEARCH

Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

(2017) Xuekun Li et al.   Nature Communications

The serum protein levels of the tPA–BDNF pathway are implicated in depression and antidepressant treatment

(2017) H Jiang et al.   Translational Psychiatry

Metformin Activates AMPK through the Lysosomal Pathway

(2016) Chen-Song Zhang et al.   Cell Metabolism

AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis

(2016) Qiyuan Yang et al.   Cell Metabolism

BDNF – a key transducer of antidepressant effects

(2016) Carl Björkholm et al.   NEUROPHARMACOLOGY

Antidiabetic drugs restore abnormal transport of amyloid-β across the blood–brain barrier and memory impairment in db / db mice

(2016) Fang Chen et al.   NEUROPHARMACOLOGY

Chronic stress-induced memory deficits are reversed by regular exercise via AMPK-mediated BDNF induction

(2016) D.-M. Kim et al.   NEUROSCIENCE

Metformin pretreatment enhanced learning and memory in cerebral forebrain ischaemia: the role of the AMPK/BDNF/P70SK signalling pathway

(2016) Negar Ghadernezhad et al.   PHARMACEUTICAL BIOLOGY

Behavioral sequelae of astrocyte dysfunction: focus on animal models of schizophrenia

(2016) Meng Xia et al.   SCHIZOPHRENIA RESEARCH

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes

(2016) Shi-Ying Yuan et al.   PLoS One

Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor

(2015) N. Miyamoto et al.   JOURNAL OF NEUROSCIENCE

Metformin improves anxiety-like behaviors through AMPK-dependent regulation of autophagy following transient forebrain ischemia

(2015) Alireza Sarkaki et al.   METABOLIC BRAIN DISEASE

Antidepressant effects of exercise are produced via suppression of hypocretin/orexin and melanin-concentrating hormone in the basolateral amygdala

(2015) Tae-Kyung Kim et al.   NEUROBIOLOGY OF DISEASE

Combined use of spatial restraint stress and middle cerebral artery occlusion is a novel model of post-stroke depression in mice

(2015) Gaocai Zhang et al.   Scientific Reports

Effects of chronic social defeat stress on peripheral leptin and its hypothalamic actions

(2014) Wataru Iio et al.   BMC NEUROSCIENCE

Unpredictable chronic mild stress induces anxiety and depression-like behaviors and inactivates AMP-activated protein kinase in mice

(2014) Shenghua Zhu et al.   BRAIN RESEARCH

Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide

(2014) Krzysztof Łabuzek et al.   Pharmacological Reports

Loss of Ahi1 Impairs Neurotransmitter Release and Causes Depressive Behaviors in Mice

(2014) Liyan Ren et al.   PLoS One

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

(2013) G Quesseveur et al.   Translational Psychiatry

Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation

(2012) Jing Wang et al.   Cell Stem Cell

Imipramine Induces Brain-Derived Neurotrophic Factor mRNA Expression in Cultured Astrocytes

(2012) Katsura Takano et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

(2012) H Yang et al.   ONCOGENE

Age-related changes in AMP-activated protein kinase after stroke

(2011) Fudong Liu et al.   AGE

Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo

(2011) Young Min Kim et al.   ATHEROSCLEROSIS

Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences

(2010) Baldeep Kumar et al.   PSYCHOPHARMACOLOGY

Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding Protein

(2009) Ling He et al.   CELL

AMPK as a mediator of hormonal signalling

(2009) Chung Thong Lim et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Activation of AMP-activated protein kinase by kainic acid mediates brain-derived neurotrophic factor expression through a NF-kappaB dependent mechanism in C6 glioma cells

(2008) Hana Yoon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

(2008) Mounira Banasr et al.   BIOLOGICAL PSYCHIATRY