Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization

Classical NF-κB pathway is responsible for APOBEC3B expression in cancer cells

(2016) Wataru Maruyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis

(2016) D. Samanta et al.   CANCER RESEARCH

Regulation of the breast cancer stem cell phenotype by hypoxia-inducible factors

(2015) G. L. Semenza   CLINICAL SCIENCE

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

(2015) Haiquan Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

(2015) Lisha Xiang et al.   Oncotarget

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Hypoxia-Inducible Factor 1 and Cardiovascular Disease

(2013) Gregg L. Semenza   Annual Review of Physiology

Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation

(2013) Lisha Xiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer

(2013) Lisha Xiang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Role of Glutathione in Cancer Progression and Chemoresistance

(2013) Nicola Traverso et al.   Oxidative Medicine and Cellular Longevity

Cancer stem cells and their role in metastasis

(2013) Yusuke Shiozawa et al.   PHARMACOLOGY & THERAPEUTICS

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression

(2012) I. Mylonis et al.   JOURNAL OF CELL SCIENCE

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways

(2011) Nadine Rohwer et al.   DRUG RESISTANCE UPDATES

HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

(2011) H Zhang et al.   ONCOGENE

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

(2011) C. C.-L. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Metabolism: Is Glutamine Sweeter than Glucose?

(2010) Weiqin Lu et al.   CANCER CELL

Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation

(2010) Jian-Bin Wang et al.   CANCER CELL

ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

(2010) Paul Mak et al.   CANCER CELL

Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model

(2010) Laura M. Shelton et al.   INTERNATIONAL JOURNAL OF CANCER

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming

(2010) F Zhao et al.   ONCOGENE

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

Oxygen homeostasis

(2009) Gregg L. Semenza   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

(2008) E. Furuta et al.   CANCER RESEARCH

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL