Protonation-Driven Membrane Insertion of a pH-Low Insertion Peptide

pH-Selective Cytotoxicity of pHLIP-Antimicrobial Peptide Conjugates

(2016) Kelly E. Burns et al.   Scientific Reports

Noncanonical Amino Acids to Improve the pH Response of pHLIP Insertion at Tumor Acidity

(2015) Joab O. Onyango et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of Cancer Cell Proliferation and Breast Tumor Targeting of pHLIP–Monomethyl Auristatin E Conjugates

(2015) Kelly E. Burns et al.   MOLECULAR PHARMACEUTICS

Modeling an In-Register, Parallel “Iowa” Aβ Fibril Structure Using Solid-State NMR Data from Labeled Samples with Rosetta

(2015) Nikolaos G. Sgourakis et al.   STRUCTURE

Residue-specific structures and membrane locations of pH-low insertion peptide by solid-state nuclear magnetic resonance

(2015) Nicolas S. Shu et al.   Nature Communications

pH-dependent random coil 1H, 13C, and 15N chemical shifts of the ionizable amino acids: a guide for protein pK a measurements

(2014) Gerald Platzer et al.   JOURNAL OF BIOMOLECULAR NMR

Evaluation of pH at Charged Lipid/Water Interfaces by Heterodyne-Detected Electronic Sum Frequency Generation

(2014) Achintya Kundu et al.   Journal of Physical Chemistry Letters

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

(2014) Christopher J. Cheng et al.   NATURE

Targeting diseased tissues by pHLIP insertion at low cell surface pH

(2014) Oleg A. Andreev et al.   Frontiers in Physiology

Aspartate Embedding Depth Affects pHLIP’s Insertion pKa

(2013) Justin Fendos et al.   BIOCHEMISTRY

Antiproliferative Effect of pHLIP-Amanitin

(2013) Anna Moshnikova et al.   BIOCHEMISTRY

Peptide targeting and imaging of damaged lung tissue in influenza-infected mice

(2013) Na Li et al.   Future Microbiology

pHLIP®-mediated delivery of PEGylated liposomes to cancer cells

(2013) Lan Yao et al.   JOURNAL OF CONTROLLED RELEASE

Family of pH (low) insertion peptides for tumor targeting

(2013) D. Weerakkody et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody-Drug Conjugates in Cancer Therapy

(2012) Eric L. Sievers et al.   Annual Review of Medicine

Modulation of the pHLIP Transmembrane Helix Insertion Pathway

(2012) Alexander G. Karabadzhak et al.   BIOPHYSICAL JOURNAL

pH (low) insertion peptide (pHLIP) targets ischemic myocardium

(2012) E. A. Sosunov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane physical properties influence transmembrane helix formation

(2012) F. N. Barrera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning a Polar Molecule for Selective Cytoplasmic Delivery by a pH (Low) Insertion Peptide

(2011) Dayanjali Wijesinghe et al.   BIOCHEMISTRY

Roles of Carboxyl Groups in the Transmembrane Insertion of Peptides

(2011) Francisco N. Barrera et al.   JOURNAL OF MOLECULAR BIOLOGY

pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path

(2010) O. A. Andreev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation

(2010) M. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solid-state NMR study of membrane interactions of the pore-forming cytolysin, equinatoxin II

(2009) Alison Drechsler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tuning the insertion properties of pHLIP

(2009) Monika Musial-Siwek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bilayer Interactions of pHLIP, a Peptide that Can Deliver Drugs and Target Tumors

(2008) Manuela Zoonens et al.   BIOPHYSICAL JOURNAL

Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane

(2008) Y. K. Reshetnyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA