Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in STAT2 KO Syrian Hamsters

Comparative Histopathologic Lesions of the Male Reproductive Tract during Acute Infection of Zika Virus in AG129 and Ifnar−/− Mice

(2018) Chad S. Clancy et al.   AMERICAN JOURNAL OF PATHOLOGY

Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study

(2018) John H Beigel et al.   LANCET INFECTIOUS DISEASES

Small-Animal Models of Zika Virus

(2017) Justin G Julander et al.   JOURNAL OF INFECTIOUS DISEASES

Monoclonal Antibodies against Zika Virus: Therapeutics and Their Implications for Vaccine Design

(2017) Qihui Wang et al.   JOURNAL OF VIROLOGY

Antibody Preparations from Human Transchromosomic Cows Exhibit Prophylactic and Therapeutic Efficacy against Venezuelan Equine Encephalitis Virus

(2017) Christina L. Gardner et al.   JOURNAL OF VIROLOGY

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques

(2017) Diogo M. Magnani et al.   Science Translational Medicine

Zika virus infection of adult and fetal STAT2 knock-out hamsters

(2017) Venkatraman Siddharthan et al.   VIROLOGY

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

(2017) Shashank Tripathi et al.   PLoS Pathogens

Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis

(2017) Zi-Yang Sheng et al.   Frontiers in Cellular and Infection Microbiology

Health and Development at Age 19–24 Months of 19 Children Who Were Born with Microcephaly and Laboratory Evidence of Congenital Zika Virus Infection During the 2015 Zika Virus Outbreak — Brazil, 2017

(2017) Ashley Satterfield-Nash et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice

(2016) Wenqiang Ma et al.   CELL

Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study

(2016) Guilherme Calvet et al.   LANCET INFECTIOUS DISEASES

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

(2016) Gopal Sapparapu et al.   NATURE

Zika Virus Infection in Pregnant Women in Rio de Janeiro

(2016) Patrícia Brasil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo

(2016) Thomas Luke et al.   Science Translational Medicine

Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus

(2016) Q. Wang et al.   Science Translational Medicine

Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus

(2016) J. A. Swanstrom et al.   mBio

The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

(2016) Joanna Zmurko et al.   PLoS Neglected Tropical Diseases

Adenosine Analog NITD008 Is a Potent Inhibitor of Zika Virus

(2016) Yong-Qiang Deng et al.   Open Forum Infectious Diseases

Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle

(2016) John M. Dye et al.   Scientific Reports

Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses

(2015) Callie E. Bounds et al.   PLoS One

Inhibition of West Nile Virus by Calbindin-D28k

(2014) Venkatraman Siddharthan et al.   PLoS One

Efficient Gene Targeting in Golden Syrian Hamsters by the CRISPR/Cas9 System

(2014) Zhiqiang Fan et al.   PLoS One

DNA vaccine-derived human IgG produced in transchromosomal bovines protect in lethal models of hantavirus pulmonary syndrome

(2014) J. W. Hooper et al.   Science Translational Medicine

Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle

(2013) Akiko Sano et al.   PLoS One