Prediction of human pharmacokinetics of long half-life compounds using chimeric mice with humanised liver

Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver

(2018) Keigo Nakayama et al.   XENOBIOTICA

Comparison of predictability for human pharmacokinetics parameters among monkeys, rats, and chimeric mice with humanised liver

(2017) Maki Miyamoto et al.   XENOBIOTICA

Systematic Evaluation of Wajima Superposition (Steady-State Concentration to Mean Residence Time) in the Estimation of Human Intravenous Pharmacokinetic Profile

(2016) Franco Lombardo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Simulation of human plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling

(2016) Hidetaka Kamimura et al.   XENOBIOTICA

PharmGKB summary

(2013) Daniel J. Klein et al.   Pharmacogenetics and Genomics

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 2: Clearance

(2012) Franco Lombardo et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 1: Volume of Distribution at Steady State

(2012) Franco Lombardo et al.   JOURNAL OF CLINICAL PHARMACOLOGY

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

(2011) Ragini Vuppugalla et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Phase I Trial of Pazopanib in Patients with Advanced Cancer

(2009) H. I. Hurwitz et al.   CLINICAL CANCER RESEARCH

Potential interactions between cilostazol and probucol: A two-part, single-dose, open-label study in healthy Korean male volunteers

(2009) Kyu-pyo Kim et al.   CLINICAL THERAPEUTICS

Prediction of Human Disposition toward S-3H-Warfarin using Chimeric Mice with Humanized Liver

(2009) Tae Inoue et al.   Drug Metabolism and Pharmacokinetics

Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches

(2009) Natilie A. Hosea et al.   JOURNAL OF CLINICAL PHARMACOLOGY