Semaphorin 4D promotes the proliferation and metastasis of bladder cancer by activating the PI3K/AKT pathway

Epidermal Growth Factor Receptor Family Inhibition Identifies P38 Mitogen-activated Protein Kinase as a Potential Therapeutic Target in Bladder Cancer

(2018) Regina Mora Vidal et al.   UROLOGY

Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA biological response modifier

(2016) Patrick Vianna Garcia et al.   BMC CANCER

Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer

(2016) Ying-Hua Yang et al.   PLoS One

Safety, Pharmacokinetics, and Pharmacodynamics of a Humanized Anti-Semaphorin 4D Antibody, in a First-In-Human Study of Patients with Advanced Solid Tumors

(2015) A. Patnaik et al.   CLINICAL CANCER RESEARCH

Generation and preclinical characterization of an antibody specific for SEMA4D

(2015) Terrence L. Fisher et al.   mAbs

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

(2015) Branden S Moriarity et al.   NATURE GENETICS

Pro-apoptotic and anti-proliferative effects of mitofusin-2 via PI3K/Akt signaling in breast cancer cells

(2015) LI MA et al.   Oncology Letters

Overexpression of Semaphorin4D Indicates Poor Prognosis and Prompts Monocyte Differentiation toward M2 Macrophages in Epithelial Ovarian Cancer

(2014) Ying Chen et al.   Asian Pacific Journal of Cancer Prevention

Expression and clinical significance of Semaphorin4D in non-small cell lung cancer and its impact on malignant behaviors of A549 lung cancer cells

(2014) Sha-sha Ruan et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Semaphorin 4D expression is associated with a poor clinical outcome in cervical cancer patients

(2014) Huidong Liu et al.   MICROVASCULAR RESEARCH

Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer

(2013) Kamal S. Saini et al.   CANCER TREATMENT REVIEWS

An expanded role for semaphorin 4D in platelets includes contact-dependent amplification of Clec-2 signaling

(2013) K. M. Wannemacher et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions

(2012) Prasanta K. Hota et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Semaphorin 4D, a lymphocyte semaphorin, enhances tumor cell motility through binding its receptor, plexinB1, in pancreatic cancer

(2011) Shingo Kato et al.   CANCER SCIENCE

Sema4D, the Ligand for Plexin B1, Suppresses c-Met Activation and Migration and Promotes Melanocyte Survival and Growth

(2011) Joanne Soong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

(2008) Jose Rafael Sierra et al.   JOURNAL OF EXPERIMENTAL MEDICINE