Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 44, Issue 5, Pages 387-390Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2019.01.004
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Funding
- European Research Council under the EU Horizon 2020 research and innovation program [714366]
- Australian Research Council Discovery Early Career Researcher Award [DE150100784]
- National Health and Medical Research Council of Australia (NHMRC) [APP1126378]
- NHMRC Australia [1083480, 1139366, 1140297]
- National Health and Medical Research Council of Australia [1139366, 1140297, 1083480] Funding Source: NHMRC
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The trefoil factor family of peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. However, major gaps in understanding their molecular function have hampered therapeutic development for gastrointestinal disorders. We provide here a critical overview of the status quo.
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