Article
Materials Science, Biomaterials
Shaojie Chen, Yanjuan Zhang, Biao Ma, Jiuzhou Chen, Jingzhe Hao, Feng Zhang, Chang Cui, Minglong Chen
Summary: Ultrasound-guided needle interventions play a crucial role in clinical diagnosis and treatment. This study developed an echogenic needle through electrolysis technology, which successfully achieved a balance between effectiveness, ease of manufacturing, and inexpensiveness. The results showed that the needle, subjected to 40 seconds of electrolysis, demonstrated both safe and effective enhancement of ultrasound visualization.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Clinical Neurology
Angela Puma, Nicolae Grecu, Luisa Villa, Catherine Butori, Thomas Besson, Chiara Cambieri, Michele Cavalli, Nicolas Azulay, Sabrina Sacconi, Charles Raffaelli
Summary: This study compared ultra-high-frequency ultrasound (UHF-US) with histologic findings in progressive polyneuropathies, demonstrating that UHF-US can accurately identify nerve inflammation in neuropathies and provide valuable information.
Article
Oncology
Katarzyna Sylwia Dobruch-Sobczak, Hanna Piotrzkowska-Wroblewska, Piotr Karwat, Ziemowit Klimonda, Ewa Markiewicz-Grodzicka, Jerzy Litniewski
Summary: The combination of B-mode ultrasound with quantitative parameters such as Kullback-Leibler divergence proved to accurately predict treatment response in breast cancer patients undergoing neoadjuvant chemotherapy, with high sensitivity and specificity.
Article
Agriculture, Dairy & Animal Science
S. L. Vieira, C. T. Simoes, L. Kindlein, T. Z. Ferreira, P. Soster, C. Stefanello
Summary: The research found that the development of wooden breast myopathy in broilers is affected by the varying energy and protein content in their feed during early growth stages. Ultrasound images of the breast muscle can serve as an early predictor for wooden breast myopathy.
Article
Medicine, General & Internal
Pawel Osemlak, Grzegorz Jedrzejewski, Magdalena Wozniak, Pawel Nachulewicz
Summary: The study aimed to verify the usefulness of spectral Doppler ultrasonography in determining the development of testis after torsion in boys. It presents a new approach to the issue of long-term gonadal blood supply abnormalities after treatment of testicular torsion in childhood, but found no clear correlation between the type of testicular torsion, its duration, and the echogenicity of the testis.
Article
Cardiac & Cardiovascular Systems
Lars Lind
Summary: The study found that IMT and IM-GSM are related to multiple metabolites from different chemical classes, with some metabolites improving the discriminatory ability for IM-GSM. However, further investigation is needed to determine if any of these metabolites are involved in the pathogenesis of carotid arteriopathy.
Article
Veterinary Sciences
Giulia Siena, Francesca di Nardo, Barbara Contiero, Tommaso Banzato, Chiara Milani
Summary: The objective of this study was to assess the changes in echogenicity of canine fetal kidneys in relation to days before parturition, maternal size, and litter size. The results showed that echogenicity was influenced by days before parturition, maternal size, and litter size.
VETERINARY SCIENCES
(2023)
Article
Acoustics
Bonhye Koo, Yunbo Liu, Monica Abboud, Bin Qin, Yong Wu, Stephanie Choi, Darby Kozak, Jiwen Zheng
Summary: This study investigated the effects of UCA gas bubble size distribution and concentration on the generated ultrasound echogenicity signal. The findings suggest that the volume-weighted size and concentration of the bubbles are more sensitive to changes in UCA bubble stability. The echogenicity signal correlates most with the volume-weighted concentration of the UCA bubbles.
Article
Medicine, General & Internal
Felix Klawitter, Uwe Walter, Robert Patejdl, Josefine Endler, Daniel A. Reuter, Johannes Ehler
Summary: This study compared the qualitative assessment by the Heckmatt scale and quantitative greyscale analysis of muscle echogenicity in detecting ICU-AW. The results showed that qualitative MUS analysis seemed superior to quantitative greyscale analysis for detecting ICU-AW.
Review
Medicine, General & Internal
Saeed Jerban, Victor Barrere, Michael Andre, Eric Y. Chang, Sameer B. Shah
Summary: This review article describes the quantitative ultrasound (QUS) techniques for peripheral nerves, including B-mode echogenicity measurements, ultrasound elastography, and the characterization of raw backscattered ultrasound radiofrequency (RF) signals. QUS techniques allow the objective evaluation of peripheral nerves and reduce biases that can influence qualitative B-mode imaging. The strengths and limitations of applying QUS techniques to peripheral nerves are discussed.
Article
Nutrition & Dietetics
Alejandro Sanz-Paris, Mikel Gonzalez-Fernandez, Luis Enrique Hueso-Del Rio, Eduardo Ferrer-Lahuerta, Alejandra Monge-Vazquez, Francisco Losfablos-Callau, Teresa Sanclemente-Hernandez, Alejandro Sanz-Arque, Jose Miguel Arbones-Mainar
Summary: This study found that muscle thickness and echogenicity were associated with malnutrition, sarcopenia, and functional capacity in acute hospital admission for a hip fracture. Specifically, masseter thickness was linked to dysphagia risk, biceps thickness to self-feeding ability, and quadriceps RF-VI thickness to mobility.
Article
Clinical Neurology
Natalie Winter, Debora Vittore, Burkhard Gess, Jorg B. Schulz, Alexander Grimm, Maike F. Dohrn
Summary: In this study, nerve and muscle ultrasound parameters were used as recognition and progression markers in 150 patients with genetically confirmed hereditary neuropathies. The study found that nerve ultrasound can help distinguish different types of hereditary neuropathies by pattern recognition, while muscle ultrasound is an objective parameter for assessing disease severity. Additionally, the implementation of neuromuscular ultrasound could enrich diagnostic procedures in both clinical routines and research.
Article
Acoustics
Steven J. Obst, Kaysie Florance, Lee Barber
Summary: This study investigated the relationship between muscle echogenicity and geometry in young, typically developing children. The results showed moderate to strong correlations between muscle thickness and echo intensity, moderate correlations between echo intensity and muscle cross-sectional area, and weak correlations between echo intensity and muscle width. Normalisation of echogenicity to muscle thickness may help differentiate between contractile and non-contractile tissue regions and provide a useful measure of muscle echogenicity when comparing muscles of different dimensions.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Jong Woo Kang, Jong Woong Park, Tae Hyun Lim, Keun Tae Kim, Song Joo Lee
Summary: This study investigated the physiological changes in a newly developed in vivo porcine acute atraumatic CS model. The results showed that shear wave elastography may serve as a non-invasive diagnostic tool for atraumatic CS, with potential value in diagnosing the condition.
SCIENTIFIC REPORTS
(2021)
Article
Rheumatology
Sara C. Croca, Maura Griffin, Filipa Farinha, David A. Isenberg, Andrew Nicolaides, Anisur Rahman
Summary: Patients with SLE have an increased risk of developing cardiovascular disease, with studies showing increased carotid plaques and greater IMT compared to healthy controls. TPA and plaque echogenicity may be more relevant to cardiovascular risk. Longitudinal studies are needed to determine the value of these measures in managing cardiovascular risk in SLE.
Article
Chemistry, Physical
Miryam Criado-Gonzalez, Deborah Wagner, Muhammad Haseeb Iqbal, Aymeric Ontani, Alain Carvalho, Marc Schmutz, Joseph B. Schlenoff, Pierre Schaaf, Loic Jierry, Fouzia Boulmedais
Summary: The spatial control of supramolecular self-assembly plays a vital role in the design of artificial cells, with the study demonstrating the successful self-assembly of phosphorylated peptides on complex coacervate microdroplets. This process leads to the formation of structured peptide/PAH capsules and fibrillar self-assembled structures at interfaces, showing potential for the development of compartmentalized structures in artificial cells.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Polymer Science
Jennifer Rodon Fores, Alexis Bigo-Simon, Deborah Wagner, Mathilde Payrastre, Camille Damestoy, Lucille Blandin, Fouzia Boulmedais, Julien Kelber, Marc Schmutz, Morgane Rabineau, Miryam Criado-Gonzalez, Pierre Schaaf, Loic Jierry
Summary: Hydrogel coatings are ideal for biomaterial design due to their biocompatibility and ability to carry biologically active compounds. Using localized enzyme-assisted self-assembly, supramolecular hydrogels can be guided effectively, with hyaluronic acid impacting internal structure and cell adhesion.
Article
Chemistry, Physical
Madeline Vauthier, Marc Schmutz, Christophe Alexandre Serra
Summary: Monomodal Janus nanoparticles with hydrophobic and hydrophilic charged domains were successfully prepared using an elongational-flow micromixer method.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Physical
Martin Fauquignon, Elise Courtecuisse, Romane Josselin, Angela Mutschler, Annie Brulet, Marc Schmutz, Jean-Francois Le Meins
Summary: The membrane structuration of Large Hybrid Unilamellar Polymer/Lipid Vesicle (LHUV) plays a crucial role in optimizing their properties and evaluating their value in various fields. This study focuses on the development of LHUV from the self-assembly of diblock poly(dimethylsiloxane)-b-poly(ethylene oxide) (PDMS-b-PEO) of different molar masses combined with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC). Techniques such as small-angle neutron scattering (SANS) and cryo-transmission electron microscopy (cryo-TEM) were utilized to characterize the hybrid vesicles and their membrane structure, showing that the membrane permeability of LHUV is primarily controlled by the lipid/polymer composition.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Physical
Theo Merland, Clement Drou, Stephanie Legoupy, Lazhar Benyahia, Marc Schmutz, Taco Nicolai, Christophe Chassenieux
Summary: This study proposes the use of an emulsification-evaporation process with an amphiphilic polymer to disperse high concentration of C60 fullerene in water. By adjusting the concentrations of polymer and fullerene, the solvent type, and the volume fraction of the organic phase, stable suspensions of fullerene nanoparticles with a concentration as high as 8 g/L are obtained.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Alessandra Zizzari, Ermelinda Bloise, Elisabetta Perrone, Diego Romano Perinelli, Marc Schmutz, Valentina Arima, Giuseppe Mele, Luigi Carbone
Summary: This study demonstrates a microfluidic method for assembling cardanol and cholesterol into amphiphile nanostructures. Compared to conventional methods, this approach allows for more efficient production of monodisperse nanostructures and is more sustainable.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Nanoscience & Nanotechnology
Yitayal Admassu Workie, Cheng-Yu Kuo, Juwita Herlina Riskawati, Nattinee Krathumkhet, Toyoko Imae, Masaki Ujihara, Marie Pierre Krafft
Summary: In this study, a series of assembled nanocomposites were prepared by functionalizing graphene oxide, single-walled carbon nanohorn, and nitrogen-doped CNH with fluorinated poly(ethylene glycol) and/or a fluorinated dendrimer. These nanocomposites provide effective multisite O2 reservoirs and show improved O2 uptake after coating with fluorinated materials. The best performance was obtained with the nanocomposite consisting of nitrogen-doped CNH coated with both fluorinated dendrimer and fluorinated poly(ethylene glycol).
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Physical
Cuong Minh Quoc Le, Marc Schmutz, Abraham Chemtob
Summary: By investigating the relationship between different monomers, it is found that above the critical micellar concentration, there is an exponential relationship between the number of particles and surfactant concentration, with the exponent depending on the polarity of the monomers. When one of the two monomers is highly hydrophobic, the exponent is generally higher.
COLLOID AND POLYMER SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Hiraku Tabata, Daisuke Koyama, Mami Matsukawa, Marie Pierre Krafft, Kenji Yoshida
Summary: This study investigated the relationship between the adsorption conditions of Pluronic F-68 and the viscoelastic properties as well as oscillation characteristics of microbubbles. The experimental results showed that when the concentration of Pluronic F-68 was below 2.0 x 10-2 mol L-1, the oscillation characteristics exhibited a sharp peak, while above this concentration, the peak flattened. By fitting the experimental data, it was found that the elasticity and viscosity of the shell significantly increased at approximately 2.0 x 10-2 mol L-1. This suggests that the adsorption properties of Pluronic F-68 strongly influence the oscillation characteristics of microbubbles suitable for medical ultrasound diagnostics.
Review
Chemistry, Multidisciplinary
Marie Pierre Krafft, Jean G. Riess
Summary: Polyhedral molecules are attractive due to their unique architecture and chemistry. Perfluorination of these compounds, which are often highly strained, poses a significant challenge as it profoundly alters their electron distribution, structure, and properties. Specifically, small high-symmetry perfluoropolyhedranes have been found to possess a centrally located, star-shaped low-energy unoccupied molecular orbital that can accommodate an extra electron, resulting in a radical anion without symmetry loss. The ability to host atoms, molecules, or ions within these cage structures is complicated, and the specific applications of perfluorinated counterparts of adamantane and cubane are yet to be determined. Some aspects of highly fluorinated carbon allotropes, such as fullerenes and graphite, are mentioned briefly for context.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Nanoscience & Nanotechnology
Robin Dufossez, Marie-Pierre Krafft, Sylvain Ursuegui, Michel Mosser, Safae Mouftakhir, Ketty Pernod, Guilhem Chaubet, Michael Ryckelynck, Alain Wagner
Summary: Droplet-based microfluidics is advancing the development of miniaturized and sensitive enzyme-linked immunosorbent assays (ELISAs). This article investigates the impact of surfactant structure on the efficiency and stability of the antibody grafting process on droplets. It demonstrates that short linkers lead to high functionalization efficiency, while long linkers enhance stability, with an intermediate size required to balance both parameters. The optimal structure is a PEG4 linker connecting a polar di-azide head and a per-fluoropolyether tail.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Alessandra Zizzari, Ermelinda Bloise, Elisabetta Perrone, Diego Romano Perinelli, Marc Schmutz, Valentina Arima, Giuseppe Mele, Luigi Carbone
Summary: This study demonstrates a microfluidic method for assembling cardanol and cholesterol into nanostructures, and highlights the significant role of cholesterol in this process.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Physical
Meriem Er-Rafik, Khalid Ferji, Jerome Combet, Olivier Sandre, Sebastien Lecommandoux, Marc Schmutz, Jean-Francois Le Meins, Carlos M. Marques
Summary: Recently, there has been increasing concern about the health risks associated with nanotechnologies, as it has been discovered that nanoparticles can reach the interior of cells and potentially disrupt cell membranes. This study reveals that small nanoparticles can tear lipid membranes, providing insight into the mechanisms by which nanoparticles can compromise membrane integrity.
Article
Materials Science, Multidisciplinary
Remy Savin, Nour-Ouda Benzaamia, Christian Njel, Sergey Pronkin, Christian Blanck, Marc Schmutz, Fouzia Boulmedais
Summary: In this study, a high sensitivity nanohybrid enzymatic biosensor was developed using a mussel-inspired method with a cheap natural molecule and gold salt. The method allows for specific functionalization of a single electrode in a microelectrode array.
MATERIALS ADVANCES
(2022)
Article
Polymer Science
Cuong Minh Quoc Le, Loic Vidal, Marc Schmutz, Abraham Chemtob
Summary: This study investigates the preparation of complex polymer colloids through miniemulsion polymerization, focusing on factors such as limited solubility and Ostwald ripening that affect droplet stability. The addition of a radical scavenger can delay polymerization, allowing for the determination of batch photopolymerization kinetics, molecular weight progress, and particle size distribution. The study emphasizes how initiator solubility, droplet size, and monomer solubility impact droplet nucleation.