Synthesis of novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation

Title
Synthesis of novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation
Authors
Keywords
Thieno[3,2-, b, ]pyridines, Sonogashira coupling, 6-, endo, -, dig, lactonization, Fused 2-pyranones, Antitumor compounds
Journal
TETRAHEDRON
Volume 75, Issue 10, Pages 1387-1397
Publisher
Elsevier BV
Online
2019-01-27
DOI
10.1016/j.tet.2019.01.054

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