Article
Oncology
Xinyue Qiu, Cheng Shen, Wenjing Zhao, Xunlei Zhang, Dakun Zhao, Yueyue Zhu, Guoxing Li, Lei Yang
Summary: This study found that a novel biomarker combining serum CEA and hemoglobin levels (HB-CEA) can serve as an independent prognostic factor for gastric cancer. It is strongly associated with clinicopathological features and survival status. Higher HB-CEA scores are correlated with poorer survival. Therefore, HB-CEA has great value in guiding clinical practice, and patients with higher scores should receive more extensive follow-up for early detection and intervention of tumor progression.
Article
Oncology
Lena Egbert, Abdullah Norain, Chee-Chee Stucky, Sarwat Ahmad, Yu-Hui Chang, Nabil Wasif
Summary: This study evaluated the impact of cancer embryonic antigen (CEA) on survival in patients with appendiceal adenocarcinoma. The results showed that elevated CEA levels were associated with worse survival and improved response to neo-adjuvant therapy.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Asahi Sato, Toshihiko Masui, Akihiro Kaneda, Akitada Yogo, Yuichiro Uchida, Takayuki Anazawa, Kazuyuki Nagai, Etsuro Hatano
Summary: This study aimed to verify the different utility of biomarkers by patients' age. They found that neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), controlling nutrition (CONUT) score, carci-noembryonic antigen (CEA), and carbohydrate antigen (CA) 19-9 had different impact on survivals in aged and young patients. NLR and CEA stratified overall survival (OS) in aged patients, whereas CONUT score and CA19-9 could stratify OS in young patients.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Oncology
Zeynep Gulsum Guc, Canan Altay, Hakan Abdullah Ozgul, Hulya Ellidokuz, Tugba Yavuzsen
Summary: GNRI and CONUT scores are elementary and practical predictors for sarcopenia, a condition which is associated with poor outcomes in mCRC patients.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Linjie Bian, Danping Wu, Yigang Chen, Jianming Ni, Huiheng Qu, Zhen Li, Xulei Chen
Summary: In this study, the associations between radiological features of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) and postoperative complications and overall survival (OS) of gastric cancer patients undergoing laparoscopic radical gastrectomy were evaluated. The results showed that a high VAT area was associated with longer operation duration, while a low VAT area and high VAT density were associated with poor prognosis.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
Sema Karakas, Gokhan Demirayak, Ayse Busra Onder, Isa Aykut Ozdemir, Cihan Comba, Sema Suzen Caypinar, Sukru Yildiz, Selim Avsar, Sema Baghaki, Gunes Ozlem Yildiz, Sakir Volkan Erdogan
Summary: The study found that patients with early-stage ovarian cancer had significantly higher levels of preoperative prognostic nutritional index (PNI) and lower controlling nutritional status (CONUT) scores.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wujie Chen, Chen Gao, Can Hu, Yao Zheng, Lijing Wang, Haibo Chen, Haitao Jiang
Summary: This study established a prognostic model for AGC patients using MRI-based radiomics, which combines age, lymphovascular invasion, and risk score to predict patients' survival. The model showed good performance in predicting 3-year and 5-year overall survival for AGC patients, and may be useful in future clinical decision-making.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Oncology
Younghoo Jo, Jae-Hoon Lee, Eun-Suk Cho, Hye Sun Lee, Su-Jin Shin, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Jeonghyun Kang
Summary: This study evaluated the prognostic significance of preoperative, postoperative, and trajectory changes in carcinoembryonic antigen (CEA) levels in patients with colorectal cancer (CRC). The study found that CEA-trend was an independent prognostic factor, with superior discriminatory power compared to CEA-pre, CEA-post, and CEA-delta. The prognostic significance of CEA-trend may vary depending on the stage of CRC.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Xin Xu, Yida Lu, Youliang Wu, Mingliang Wang, Xiaodong Wang, Huizhen Wang, Bo Chen, Yongxiang Li
Summary: This study identified a novel seven-IRGs risk signature for individualized survival prediction of male GC patients. The expression of these seven genes could reflect the status of the tumor immune microenvironment. The established risk signature model showed excellent predictive performance in evaluating the prognosis of individual male GC patients.
CANCER CELL INTERNATIONAL
(2021)
Article
Oncology
Qianyi Wan, Zhetao Wang, Rui Zhao, Tingting Tu, Xiaoding Shen, Yuhou Shen, Tao Li, Yi Chen, Yinghan Song
Summary: CT-determined low SMM is associated with overall survival (OS) in gastric cancer patients, with a more significant prediction in patients with cachexia. Patients with synchronous low SMM and cachexia need more attention.
Review
Nutrition & Dietetics
Sorayya Kheirouri, Mohammad Alizadeh
Summary: The study found that a high preoperative CONUT score is associated with a poor survival rate in cancer patients, and is an independent prognostic factor. The CONUT score shows a high prognostic competence in predicting OS, CSS, and RFS.
ADVANCES IN NUTRITION
(2021)
Article
Oncology
Hanjun Mo, Pengfei Li, Sunfang Jiang
Summary: A nomogram was established and validated for predicting the 3- and 5-year overall survival of gastric cancer patients after surgical resection. The nomogram showed excellent discrimination and confirmed the prognostic value of cardia invasion and chemotherapy.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Medicine, Research & Experimental
Toru Aoyama, Keisuke Komori, Masato Nakazano, Kentaro Hara, Hiroshi Tamagawa, Keisuke Kazama, Itaru Hashimoto, Takanobu Yamada, Yukio Maezawa, Kenki Segami, Kazuki Kano, Shinsuke Nagasawa, Norio Yukawa, Yasushi Rino, Takashi Ogata, Takashi Oshima
Summary: This study investigated the influence of CONUT score on survival and recurrence in patients with gastric cancer after curative treatment, and found that CONUT score was a predictive factor for survival.
Article
Oncology
Yuqian Chen, Rong Sun, Wanli Liu
Summary: This study aimed to evaluate the impact of a prior cancer history on the overall survival of patients with primary gastric cancer. The results showed that a previous cancer adversely affected the overall survival of gastric cancer patients, especially for those aged over 40 and those with a history of oral, pharynx, respiratory system, female genital system, or lymphoma cancer.
Article
Oncology
Chun-Yi Tsai, Keng-Hao Liu, Cheng-Tang Chiu, Shun-Wen Hsueh, Chia-Yen Hung, Jun-Te Hsu, Ngan-Ming Tsang, Yu-Shin Hung, Wen-Chi Chou
Summary: This study found that elevated AFP levels are rare in newly diagnosed gastric cancer patients and routine AFP testing does not offer better survival prediction compared to CEA or CA19-9.
ANTICANCER RESEARCH
(2021)