Article
Chemistry, Analytical
Juan Lu, Yue Wang, Xiangyu Shan, Zhuo Sun, Xin Zhang, Yingjie Zhao, Yue Hu, Erjun Sun, Li Tian
Summary: An electrochemiluminescence sensor was developed by modifying a glassy carbon electrode with multiwall carbon nanotubes, cobalt oxide doped silver oxide, and porphyrin zinc to detect glucose in biological systems. The sensor demonstrated good sensitivity, selectivity, stability, and reproducibility.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Analytical
Yanhong Xu, Zhengang Han, Peiyao Du, Xiaoquan Lu
Summary: Porphyrins have gained extensive attention as significant electrochemical luminaries due to their distinctive structure and superior photoelectric properties. However, challenges such as aggregation in aqueous phases, water insolubility, inherent instability, and weaker Q-band hinder the electrochemiluminescence applications of porphyrins. This review provides a comprehensive summary of different strategies to achieve high efficiency in porphyrin ECL and signal amplification, and presents a critical perspective on the developmental trends and future prospects of porphyrins.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Li-Yan Huang, Xiang Hu, Hong-Yan Shan, Lu Yu, Yi-Xin Gu, Ai-Jun Wang, Dan Shan, Pei-Xin Yuan, Jiu-Ju Feng
Summary: By synthesizing Zn-based metal organic frameworks with pyridine to enhance the electrochemiluminescence response of zinc meso-tetra(4-sulfonatophenyl) porphine, a biosensor with wide linear range and low detection limit was developed in this study. The Zn-TP linked Zn-Bp-MOFs showed significantly improved ECL efficiency compared to free Zn-TP, holding promise for broader applications in the field of photoelectric detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Lucy J. T. Metzroth, Elisa M. Miller, Andrew G. Norman, Sadegh Yazdi, Gerard Michael Carroll
Summary: Exploiting the high surface-area-to-volume ratio of nanomaterials to store energy in the form of electrochemical alloys shows promise, but nanoscale-specific properties affect the absorption and desorption of energy carrying equivalents. Adding an ultrathin platinum shell to the surface of palladium can greatly enhance hydrogen absorption rates and facilitate diffusion across the entire surface.
Article
Materials Science, Multidisciplinary
Suhwan Yoo, Harshavardhan Mohan, Hyeon Seung Oh, Gitae Kim, Jae R. Hahn, Taeho Shin
Summary: The synthesized Pd@PdS core shell nanocubes demonstrated high efficiency in degrading methylparaben, attributed to enhanced light absorption and charge transfer at the core-shell interface.
Article
Chemistry, Analytical
Zhengang Han, Juxia Wang, Peiyao Du, Jing Chen, Shuhui Huo, Huixia Guo, Xiaoquan Lu
Summary: Distinguishing between water (H2O) and deuteroxide (D2O) is a challenging task due to their similarities in size, shape, and chemical reactivity. This study investigates the enhanced optical properties of a water-soluble porphyrin in D2O and proposes a convenient method for distinguishing between H2O and D2O using electrochemiluminescence (ECL) analysis, which shows a lower detection limit.
ANALYTICAL CHEMISTRY
(2022)
Article
Polymer Science
Elzbieta Radzyminska-Lenarcik, Ilona Pyszka, Wlodzimierz Urbaniak
Summary: The new polymer inclusion membrane with a 1-alkyltriazole matrix shows effective separation of palladium(II) ions from aqueous chloride solutions containing a mixture of Zn-Pd-Ni ions. The stability constants and partition coefficients increase with the growing hydrophobicity of the 1-alkyltriazole molecule, with the highest values observed for Pd(II) complexes. The membrane transport studies reveal Pd(II) > Zn(II) > Ni(II) in terms of transport selectivity.
Article
Biochemistry & Molecular Biology
Xinying Zhang, Xialing Hou, Decheng Lu, Yingying Chen, Lingyan Feng
Summary: A novel and efficient carbon nanocomposite material, Porphyrin (TMPyP) functionalized carbon quantum dots (CQDs-TMPyP), was developed as a luminescent material for the sensitive detection of copper ions (Cu2+) by quenching the luminescence of functionalized carbon quantum dots. A sensitive signal off electrochemiluminescence (ECL) biosensor was constructed for the detection of Cu2+. The sensor showed sensitive response to copper ions in the range of 10 nM to 10 mu M, with a detection limit of 2.78 nM. It exhibited good selectivity, stability, and a favorable response in complex systems. This proposed ECL biosensor provides an efficient and ultrasensitive method for Cu2+ detection.
Article
Chemistry, Analytical
Xuemei Wang, Chuantao Hou, Feifei Zhang, Jianfei Xia, Zonghua Wang
Summary: In this study, a self-enhanced electrochemiluminescence (ECL) strategy was employed by generating a coreaction accelerator in situ during the synthesis of luminophores. A composite material integrating a luminophore (Zn-TCPP) and a coreaction accelerator (TiO2 NPs) was synthesized. The ECL signal was greatly improved by immobilizing a probe on the composite material, which increased the concentration of the coreactant and shortened the electron transport distance. This work not only developed a simple and ultrasensitive exosome detection system but also demonstrated a potential application of porphyrin-based metal-organic frameworks (Por-MOFs) in biological analysis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Nanoscience & Nanotechnology
Han-Tang Jhao, Cheng-Yu Zhan, Hsin-Lun Wu
Summary: In this study, intermetallic PdCd nanocubes with a face-centered tetragonal phase were synthesized, which not only preserved the catalytic activity but also exhibited an increase in catalytic activity upon illumination. The alloyed structure of the nanocubes had the maximum number of active Pd sites, and the increase in catalytic activity can be attributed to an increase in the number of s-band free electrons upon doping of Cd atoms.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Analytical
Qing Hua, Feiyan Tang, Xiaobin Wang, Min Li, Xiaowen Gu, Wenjie Sun, Feng Luan, Chunyuan Tian, Xuming Zhuang
Summary: A novel label-free ECL sensor was developed for highly sensitive and selective detection of Hg2+, achieving a linear response and low detection limit, and successfully applied in seafood detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Environmental
Qian Han, Cun Wang, Pingkun Liu, Gui Zhang, Li Song, Yingzi Fu
Summary: The study demonstrates the excellent performance and stability of three types of porphyrin dots in electrochemiluminescence, with significantly higher ECL efficiency in the S2O82- cathodic system compared to the standard. Additionally, a biosensor utilizing these porphyrin dots shows ultrasensitive detection of Pb2+.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Xinxiang Cao, Ruijian Tong, Siye Tang, Ben W-L Jang, Arash Mirjalili, Jiayi Li, Xining Guo, Jingyi Zhang, Jiaxue Hu, Xin Meng
Summary: Novel zinc-palladium-porphyrin bimetal metal-organic framework (MOF) nanosheets were synthesized and transformed into carbon-supported Pd-Zn intermetallics with different Pd: Zn atomic ratios. Pd3.9Zn6.1 showed the best catalytic performance for selective hydrogenation.
Article
Engineering, Environmental
Yang Xia, Bicheng Zhu, Xing Qin, Wingkei Ho, Jiaguo Yu
Summary: Constructing heterojunction photocatalyst is a promising strategy for solar-to-chemical energy conversion. This study designed and synthesized an S-scheme heterojunction for H2O2 production by grafting supramolecular Zinc porphyrin on g-C3N4. The results demonstrated that the Zn-TCPP/CN heterojunction exhibited significantly higher H2O2 production rate compared to pure CN and Zn-TCPP, attributed to the efficient charge separation and inhibition of charge recombination. This work provides inspiration for the design of high-active metalloporphyrin-based S-scheme heterojunctions for energy conversion.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Bruna S. Sa, Cecilia A. Zito, Tarcisio M. Perfecto, Diogo P. Volanti
Summary: This study successfully synthesized highly sensitive and selective NC-ZnSnO3 for TEA detection, demonstrating excellent response properties for various VOCs and a low detection limit for TEA.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Materials Science, Multidisciplinary
Nianzu Liu, Yihui Ma, Zhenying Xu, Yingshu Guo, Xiliang Luo
Summary: We report a PANI-HA hydrogel that combines rigid conducting polymer with flexible HA. The supramolecular assembly of PANI and HA via boronic acid bonds yields PANI-HA hydrogel with unique microstructure, electrical conductivity and hydrophilicity, showing excellent supercapacitor performance and electrochemical sensing for IgG. The PANI-HA hydrogel-based electrode exhibits high specific capacitance (369 F g(-1)) and good cycling stability (85% capacity retention after 1000 charge-discharge cycles). It can also be used as an electrochemical biosensor for IgG detection with good sensitivity, wide detection range, and low detection limit.
JOURNAL OF MATERIALS SCIENCE
(2023)
Editorial Material
Chemistry, Analytical
Xiliang Luo
Article
Chemistry, Multidisciplinary
Sai Zhang, Ping Chen, Yu Fan, Yan Zhao, Wenlong Yang, Hongtao Gao, Xiliang Luo
Summary: This study successfully synthesized amorphous and crystalline NiS2 nanospheres using a simple method and found that the amorphous structure of NiS2 catalyst has superior electrochemical activity for methanol oxidation reaction compared to the crystalline counterpart.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Lei Zhang, Han Liu, Qianyao Du, Guoqiang Zhang, Shanhui Zhu, Zhongtao Wu, Xiliang Luo
Summary: Photoresponsive phase change materials have the ability to store and release both photon and heat energy. By designing azobenzene surfactants at the molecular level, it is possible to achieve high gravimetric energy density and enhance molar isomerization enthalpy.
Article
Chemistry, Analytical
Xiqin Yang, Ping Chen, Xi Zhang, Hao Zhou, Zhen Song, Wenlong Yang, Xiliang Luo
Summary: A simple tactic for electrochemical determination of HER2, a typical biomarker for breast cancer, was developed through the construction of a low fouling sensing interface functionalized with PEG and peptide. The biosensor exhibited strong antifouling performances in complex biofluids due to the combined effect of PEG and peptide, and it had an ultralow limit of detection and a wide linear range for HER2 assay. The combination of PEG and peptide provided an effective strategy for the development of low fouling sensing platforms in complex biotic environments.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xiao-Long Zhang, Sha-Sha Li, Yi-Jia Liu, Wei-Wei Liu, Ling-Qi Kong, Ya-Qin Chai, Xi-Liang Luo, Ruo Yuan
Summary: An ingenious three-dimensional DNA walker with high walking efficiency is developed by limiting the reaction space, providing a rapid and sensitive detection method for miRNA. Compared to traditional DNA walkers, this immobilized DNA walker shows improved kinetic and thermodynamic favorability, resulting in faster reaction speed and higher walking efficiency. By utilizing this walker, a sensitive sensing platform for rapid miRNA-21 detection is constructed with a limit of detection of 19.8 aM, allowing for highly sensitive biomarker detection in cancer cell lysates.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Yanxin Li, Shuju Zhao, Zhenying Xu, Xiujuan Qiao, Mingxuan Li, Youke Li, Xiliang Luo
Summary: A non-fouling electrochemical biosensor was constructed using antifouling peptides and electroneutral PNA as the recognizing probe for SARS-CoV-2 viral RNA. The biosensor exhibited remarkable sensitivity with a broad linear range (1.0 fM -1.0 nM) and a low detection limit of 0.38 fM. This study provided a new strategy for developing non-fouling sensing systems capable of detecting trace disease biomarkers in complex biological media.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Shuju Zhao, Zhen Song, Tao Liu, Xin Wang, Yanxin Li, Yaqun Xu, Hao Wang, Yumin Wu, Xiliang Luo
Summary: Zwitterionic peptides with strong water binding ability have been designed to construct antifouling biosensors with enhanced stability in complex biological fluids. The designed peptides demonstrated much stronger antifouling capability and significantly enhanced stability in human serum and blood. Furthermore, the biosensor integrating the designed antifouling peptide with CEA aptamer exhibited a great sensitivity for detecting CEA protein, making it promising for practical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Nianzu Liu, Ruoxing Wang, Shengjie Gao, Ruifang Zhang, Fengru Fan, Yihui Ma, Xiliang Luo, Dong Ding, Wenzhuo Wu
Summary: Leveraging mechanically-induced piezoelectric polarization, piezocatalysis emerges as a viable mechanism for enhancing catalytic processes. Nanostructured, catalytically active, rationally designed piezo-electric semiconductors can achieve high-performance catalysts for various applications using cost-effective electrocatalytic pathways, such as mechanical stimuli. The facile synthesis of high-quality ZnO nanostructures enables low-cost, scalable manufacture and direct integration into electrocatalysts for enhanced performance.
Article
Chemistry, Analytical
Yaqun Xu, Xiujuan Qiao, Zhi-Ling Song, Gao-Chao Fan, Xiliang Luo
Summary: A robust photoelectrochemical (PEC) biosensor capable of accurate detection in human serum was developed by integrating a new engineered branching peptide (EBP) into a synergetic dual-photoelectrode system. The biosensor exhibited high sensitivity, specificity, and anti-interference properties.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Fu-Hui Lyu, Chen-Chen Li, Yue Li, Lin Cui, Xi-Liang Luo
Summary: Metal-organic gels (MOGs) are gel materials formed by bridging metal ions and organic ligands via non covalent interactions. They have advantages such as easy preparation, large specific surface area, tunable structure, and abundant metal sites, making them widely used in sensing, analysis, catalysis, adsorption, energy storage and electrochromic devices. This paper reviews the progress in the research and application of MOGs in these fields, and discusses the challenges, future trends and application prospects.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: A DNA sensing platform with endogenous stimuli-responsive and ultrasensitive characteristics, incorporating a logic gate biocomputation, has been developed for precise cell subtype identification in disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Rui Han, Wenjie Hou, Yang Li, Min Chen, Caifeng Ding, Xiliang Luo
Summary: A sensitive electrochemical biosensor based on a self-designed cyclic peptide is capable of detecting the RBD antigen in human blood. The cyclic peptide possesses excellent antifouling properties and strong anti-enzymatic hydrolysis ability, making the biosensor stable and reliable for COVID-19 antigen testing.
SENSORS & DIAGNOSTICS
(2023)
Article
Biophysics
Ze Hu, Hao Wang, Huimin Chen, Gao-Chao Fan, Xiliang Luo
Summary: In this study, an ingenious approach of target-triggered cascade signal amplification in porous anodic aluminum oxide nanochannels was developed for ultrasensitive photoelectrochemical DNA bioanalysis. The innovative nanochannels PEC strategy launched a novel detecting platform for trace levels of DNA, providing a potential inspiration for other smart nanochannels PEC bioassays.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)