Article
Multidisciplinary Sciences
Rina Fujimaki, Noritoshi Suzuki, Katsunori Kimoto, Yukiko Nagai, Yuya Oaki, Shinji Shimode, Takashi Toyofuku, Hiroaki Imai
Summary: The micrometric arrangement and nanometric structure of the radiolarian crystalline spines were clarified using microfocus X-ray computed tomography. The acantharian skeleton is composed of 20 radial spines with four blades, covered by a chitin-based organic membrane.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Manufacturing
Yun Lu Tee, Jay R. Black, Phuong Tran
Summary: The morphological properties and structures of porcupine quills of different sizes were analyzed using micro-CT scans. Various segmentation methods were applied to identify the porosity variation, with deep learning segmentation proving to be the most reliable. The obtained results provide important information for biomimicry research and engineering applications.
VIRTUAL AND PHYSICAL PROTOTYPING
(2023)
Article
Clinical Neurology
Hao Li, Nadine Schart-Moren, Gunesh Rajan, Jeremy Shaw, Seyed Alireza Rohani, Francesca Atturo, Hanif M. Ladak, Helge Rask-Andersen, Sumit Agrawal
Summary: The study analyzed the 3D anatomy of the basal region of the human cochlea, vestibular apparatus, and EDS to optimize surgical approaches following cochlear implantation. Results showed that drilling during the surgery may harm the vestibular organ function by disrupting fluid barriers and injuring the endolymphatic space. Round window insertion may be a less traumatic alternative but could still affect vestibular receptors.
FRONTIERS IN NEUROLOGY
(2021)
Article
Physiology
Christian Westoo, Christian Norvik, Niccolo Peruzzi, Oscar van der Have, Goran Lovric, Ida Jeremiasen, Phan-Kiet Tran, Rajmund Mokso, Vinicio de Jesus Perez, Hans Brunnstrom, Martin Bech, Csaba Galambos, Karin Tran-Lundmark
Summary: This study used synchrotron-based imaging to study the three-dimensional structure of plexiform lesions in patients with pulmonary arterial hypertension, identifying four distinct types of plexiform lesions which likely have different effects on hemodynamics and disease progression. Types 1-3 may potentially relieve pressure via the bronchial circulation in these patients, as their pulmonary arteries were almost always occluded distally.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yousef Shahin, Samer Alabed, Dheyaa Alkhanfar, Juerg Tschirren, Alex M. K. Rothman, Robin Condliffe, James M. Wild, David G. Kiely, Andrew J. Swift
Summary: This study quantitatively analyzed CT pulmonary angiography to assess the volumes of peel pulmonary vessels and small pulmonary vessels in different subtypes of pulmonary hypertension (PH). The results showed that the volume of small pulmonary vessels is reduced in pulmonary arterial hypertension and PH associated with left heart disease, while the volume of peel vessels is similar to that of the control group. In patients with PH, the volume of small pulmonary vessels is correlated with pulmonary function tests.
Article
Materials Science, Multidisciplinary
Yi Zhao, Liying Ju, Xiaopei Guo, Tao Li, Min Tan, Han Guo, Shaopeng Gu
Summary: The three-dimensional morphology of alumina clusters in steel samples was observed using X-ray Micro-CT technology and Avizo software, revealing their actual morphology. A series of parameters were defined to characterize the morphological characteristics of alumina clusters, and fractal theory was introduced for quantitative description. This study provides an effective method for quantitative description of impurity morphology and spatial distribution, and it serves as an important reference for effective control of alumina inclusions.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Multidisciplinary Sciences
Seung Yoon Yang, Ho Seung Kim, Min Soo Cho, Nam Kyu Kim
Summary: Understanding the anatomy of Denonvilliers' fascia is crucial for successful surgical outcomes in patients with rectal cancer. The debate over whether the surgical plane during total mesorectal excision should be anterior or posterior to the fascia continues. This study utilized micro-computed tomography to reveal the relationship between Denonvilliers' fascia, mesorectal fascia, and neurovascular bundles, highlighting the importance of a posterior dissection plane for optimal oncologic results.
SCIENTIFIC REPORTS
(2021)
Article
Energy & Fuels
Michael T. Wall, Yang Ren, Travis Hesterberg, Tim Ellis, Marcus L. Young
Summary: This study evaluates the effects of minor alloying additions of Sb, As, Ca, Sn, Al, In, and Bi on the characteristics of Pb-alloy grid material, using high-energy Synchrotron radiation X-ray diffraction and electrochemical testing. The results show different alloying elements have various effects on grain growth, passivation, sulfate formation, and corrosion resistance.
JOURNAL OF ENERGY STORAGE
(2022)
Article
Energy & Fuels
Michael T. Wall, Matthew Carl, Jesse Smith, Yang Ren, Matthew Raiford, Travis Hesterberg, Tim Ellis, Marcus L. Young
Summary: This study investigates the effects of minor alloying elements on grain inhibition and phase evolution in Pb-alloy grid materials, using modern analytical techniques. The results show that Ba inhibits grain growth while Bi does not, compared to pure Pb.
JOURNAL OF ENERGY STORAGE
(2021)
Article
Thermodynamics
Yongzan Wen, Guanhua Ni, Xinyue Zhang, Yicheng Zheng, Gang Wang, Zhenyang Wang, Qiming Huang
Summary: This paper investigates the effect of acidification erosion on the pore structure of anthracite using various methods. The results show that HCl has the highest removal efficiency of minerals, leading to improved pore structure and fluid transport capacity in coal samples.
Article
Engineering, Chemical
Penghui Li, Weiqi Guo, Jinbo Fan, Chen Su, Xiuguo Zhao, Xinxi Xu
Summary: Accurately estimating the deposition of inhaled particles in the pulmonary acinus is crucial for reducing the damage of ambient aerosols or maximizing drug particles' efficacy. This study investigates the effect of wall motion and interparticle collisions on aerosol deposition in a four-generation human acinar model. The results show that both wall motion and interparticle collisions have a significant impact on particle deposition.
JOURNAL OF AEROSOL SCIENCE
(2023)
Article
Biochemical Research Methods
May Zaw Thin, Christopher Moore, Thomas Snoeks, Tammy Kalber, Julian Downward, Axel Behrens
Summary: In this paper, a method of lung nodule image acquisition and analysis using a micro-computed tomography scanner is introduced for translational research in lung cancer that closely mimics clinical environments. The method has the advantages of low radiation dose, high resolution, and high-throughput imaging, and utilizes specific image analysis tools for identifying different types of lung tumors.
Article
Materials Science, Multidisciplinary
Reng Qin, Wei Zhou, Kang-ning Han, Jia Liu, Lian-hua Ma
Summary: The study investigated the effects of near-surface delamination on the buckling response behavior of carbon fiber reinforced laminated composites under different bending modes. The results showed that the size of delamination had little influence on the ultimate bearing capacity, but the thickness of the specimen had a significant impact on the ultimate load. Acoustic emission monitoring and micro-CT imaging can effectively reflect the damage states and mechanisms of the composites.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Multidisciplinary Sciences
Daniel Salerno, Ifeoma Oriaku, Melinda Darnell, Maarten Lanclus, Jan De Backer, Ben Lavon, Rohit Gupta, Fredric Jaffe, Maria Elena Vega Sanchez, Victor Kim
Summary: Abnormalities in pulmonary vascular volumes at the time of hospitalization for COVID-19 are independently associated with a low DLCO at follow-up, while there is no relationship between inflammatory biomarkers during hospitalization and DLCO levels. Pulmonary vascular abnormalities during hospitalization for COVID-19 may serve as a biomarker for abnormal gas transfer after COVID-19 pneumonia.
Article
Chemistry, Analytical
Du-Chang Xu, Yu-Xiao Luo, Yuan-Qing Xu
Summary: This paper proposes a respiratory movement model of terminal pulmonary acini and explores the effect of gravity direction, respiratory rate, microparticle diameter, and other parameters on the microparticles deposition process. The study reveals the dynamic correlation between the respiration process and the movement of microparticles, providing reference value for understanding the pathogenicity mechanism of inhalable particles and optimizing aerosol delivery.
Article
Engineering, Biomedical
Kenichiro Koshiyama, Keisuke Nishimoto, Satoshi Ii, Toshihiro Sera, Shigeo Wada
CLINICAL BIOMECHANICS
(2019)
Article
Pharmacology & Pharmacy
Philipp Hofemeier, Kenishiro Koshiyama, Shigeo Wada, Josue Sznitman
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2018)
Article
Biophysics
Toshihiro Sera, Hiroaki Kobayashi, Masato Hoshino, Kentaro Uesugi, Takeshi Matsumoto, Masao Tanaka
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2019)
Article
Cell Biology
Toshihiro Sera, Masataka Arai, Zhonghua Cui, Koichi Onose, Alireza Karimi, Susumu Kudo
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Computer Science, Interdisciplinary Applications
Shinya Kimura, Takashi Sakamoto, Toshihiro Sera, Hideo Yokota, Kenji Ono, Denis J. Doorly, Robert C. Schroter, Gaku Tanaka
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2019)
Article
Chemistry, Physical
Kenichiro Koshiyama, Masaki Taneo, Taiki Shigematsu, Shigeo Wada
JOURNAL OF PHYSICAL CHEMISTRY B
(2019)
Article
Engineering, Biomedical
Alireza Karimi, Reza Razaghi, Toshihiro Sera, Susumu Kudo
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2019)
Article
Pharmacology & Pharmacy
Lihi Shachar-Berman, Yan Ostrovski, Kenichiro Koshiyama, Shigeo Wada, Stavros C. Kassinos, Josue Sznitman
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2019)
Article
Biochemical Research Methods
Masakazu Umezawa, Toshihiro Sera, Hideo Yokota, Maho Takematsu, Masahiko Morita, Gil Yeroslavsky, Masao Kamimura, Kohei Soga
JOURNAL OF BIOPHOTONICS
(2020)
Review
Biochemistry & Molecular Biology
Toshihiro Sera, Shiro Higa, Yan Zeshu, Kyosuke Takahi, Satoshi Miyamoto, Tetsuya Fujiwara, Hideo Yokota, Saori Sasaki, Susumu Kudo
BIOCHEMICAL JOURNAL
(2020)
Article
Physiology
Toshihiro Sera, Taiki Kohno, Yusuke Nakashima, Musashi Uesugi, Susumu Kudo
JOURNAL OF PHYSIOLOGICAL ANTHROPOLOGY
(2020)
Article
Mechanics
Jianan Zhao, Yu Feng, Kenichiro Koshiyama, Huimin Wu
Summary: A novel elastic truncated whole-lung (TWL) modeling framework has been developed to simulate disease-specific airway deformation kinematics and pulmonary air-particle flow dynamics. Results demonstrate the importance of modeling airway deformation kinetics in whole-lung models, especially for drug delivery efficiency in COPD treatment.
Article
Chemistry, Physical
Taiki Shigematsu, Kenichiro Koshiyama
Summary: Shear flow can suppress surfactant bilayer undulation and generate negative tension, which is important for the onion transition. Molecular dynamics simulations of single phospholipid bilayer under shear flow show that increasing shear rate suppresses undulation and increases negative tension, consistent with theoretical predictions. The force components of negative tension are anisotropic but the resultant tension is isotropic.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Physics, Fluids & Plasmas
Taiki Shigematsu, Kenichiro Koshiyama, Shigeo Wada