The transition to cocaine addiction: the importance of pharmacokinetics for preclinical models

Enhanced neuronal and blunted hemodynamic reactivity to cocaine in the prefrontal cortex following extended cocaine access: optical imaging study in anesthetized rats

(2018) Craig P. Allen et al.   ADDICTION BIOLOGY

Revisiting long-access versus short-access cocaine self-administration in rats: intermittent intake promotes addiction symptoms independent of session length

(2018) Florence Allain et al.   ADDICTION BIOLOGY

The neuroscience of cognitive-motivational styles: Sign- and goal-trackers as animal models.

(2018) Martin Sarter et al.   BEHAVIORAL NEUROSCIENCE

Modeling the development of drug addiction in male and female animals

(2018) Wendy J. Lynch   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Addictive behaviour in experimental animals: prospects for translation

(2018) Barry J. Everitt et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats

(2018) Morgan H. James et al.   BIOLOGICAL PSYCHIATRY

Non-pharmacological factors that determine drug use and addiction

(2018) Serge H. Ahmed et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Volitional social interaction prevents drug addiction in rat models

(2018) Marco Venniro et al.   NATURE NEUROSCIENCE

Sex differences in incentive-sensitization produced by intermittent access cocaine self-administration

(2018) Alex B. Kawa et al.   PSYCHOPHARMACOLOGY

‘Hot’ vs. ‘cold’ behavioural-cognitive styles: motivational-dopaminergic vs. cognitive-cholinergic processing of a Pavlovian cocaine cue in sign- and goal-tracking rats

(2017) Kyle K. Pitchers et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Diverse Roads to Relapse: A Discriminative Cue Signaling Cocaine Availability Is More Effective in Renewing Cocaine Seeking in Goal Trackers Than Sign Trackers and Depends on Basal Forebrain Cholinergic Activity

(2017) Kyle K. Pitchers et al.   JOURNAL OF NEUROSCIENCE

Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats?

(2017) Bryan F. Singer et al.   JOURNAL OF NEUROSCIENCE

Neuroscience Needs Behavior: Correcting a Reductionist Bias

(2017) John W. Krakauer et al.   NEURON

Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation

(2017) Florence Allain et al.   NEUROPHARMACOLOGY

Cocaine addiction as a homeostatic reinforcement learning disorder.

(2017) Mehdi Keramati et al.   PSYCHOLOGICAL REVIEW

High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats

(2017) Florence Allain et al.   PSYCHOPHARMACOLOGY

Incubation of extinction responding and cue-induced reinstatement, but not context- or drug priming-induced reinstatement, after withdrawal from methamphetamine

(2016) Sweta Adhikary et al.   ADDICTION BIOLOGY

Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine

(2016) Cody A. Siciliano et al.   JOURNAL OF NEUROSCIENCE

Synaptic mechanisms underlying persistent cocaine craving

(2016) Marina E. Wolf   NATURE REVIEWS NEUROSCIENCE

Neurobiologic Advances from the Brain Disease Model of Addiction

(2016) Nora D. Volkow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior

(2016) Alex B. Kawa et al.   PSYCHOPHARMACOLOGY

Less than meets the eye: Reappraising the clinical relevance of attentional bias in addiction

(2015) Paul Christiansen et al.   ADDICTIVE BEHAVIORS

How fast and how often: The pharmacokinetics of drug use are decisive in addiction

(2015) Florence Allain et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Excessive cocaine use results from decreased phasic dopamine signaling in the striatum

(2014) Ingo Willuhn et al.   NATURE NEUROSCIENCE

Brief Intermittent Cocaine Self-Administration and Abstinence Sensitizes Cocaine Effects on the Dopamine Transporter and Increases Drug Seeking

(2014) Erin S Calipari et al.   NEUROPSYCHOPHARMACOLOGY

Frequency of Cocaine Self-Administration Influences Drug Seeking in the Rat: Optogenetic Evidence for a Role of the Prelimbic Cortex

(2014) Elena Martín-García et al.   NEUROPSYCHOPHARMACOLOGY

Economic demand predicts addiction-like behavior and therapeutic efficacy of oxytocin in the rat

(2014) B. S. Bentzley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopamine ups and downs in vulnerability to addictions: a neurodevelopmental model

(2014) Marco Leyton et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Escalation of drug self-administration as a hallmark of persistent addiction liability

(2013) Scott Edwards et al.   BEHAVIOURAL PHARMACOLOGY

The clinical relevance of attentional bias in substance use disorders

(2013) Matt Field et al.   CNS SPECTRUMS

Substance-specific environmental influences on drug use and drug preference in animals and humans

(2013) Aldo Badiani   CURRENT OPINION IN NEUROBIOLOGY

Extended access of cocaine self-administration results in tolerance to the dopamine-elevating and locomotor-stimulating effects of cocaine

(2013) Erin S. Calipari et al.   JOURNAL OF NEUROCHEMISTRY

Psychobiology of cocaine addiction: Contribution of a multi-symptomatic animal model of loss of control

(2013) Véronique Deroche-Gamonet et al.   NEUROPHARMACOLOGY

Temporal Pattern of Cocaine Intake Determines Tolerance vs Sensitization of Cocaine Effects at the Dopamine Transporter

(2013) Erin S Calipari et al.   NEUROPSYCHOPHARMACOLOGY

A multistep general theory of transition to addiction

(2013) Pier Vincenzo Piazza et al.   PSYCHOPHARMACOLOGY

The Motivation to Self-Administer is Increased After a History of Spiking Brain Levels of Cocaine

(2012) Benjamin A Zimmer et al.   NEUROPSYCHOPHARMACOLOGY

The behavioral economics of drug self-administration: A review and new analytical approach for within-session procedures

(2012) Brandon S. Bentzley et al.   PSYCHOPHARMACOLOGY

Escalation of cocaine intake with extended access in rats: dysregulated addiction or regulated acquisition?

(2012) Joshua S. Beckmann et al.   PSYCHOPHARMACOLOGY

Contextual conditioning enhances the psychostimulant and incentive properties ofd-amphetamine in humans

(2011) Emma Childs et al.   ADDICTION BIOLOGY

Brain-Cocaine Concentrations Determine the Dose Self-Administered by Rats on a Novel Behaviorally Dependent Dosing Schedule

(2011) Benjamin A Zimmer et al.   NEUROPSYCHOPHARMACOLOGY

The science of making drug-addicted animals

(2011) S.H. Ahmed   NEUROSCIENCE

Behavioral and Functional Evidence of Metabotropic Glutamate Receptor 2/3 and Metabotropic Glutamate Receptor 5 Dysregulation in Cocaine-Escalated Rats: Factor in the Transition to Dependence

(2010) Yue Hao et al.   BIOLOGICAL PSYCHIATRY

Cocaine-Insensitive Dopamine Transporters with Intact Substrate Transport Produced by Self-Administration

(2010) Mark J. Ferris et al.   BIOLOGICAL PSYCHIATRY

Ambience and Drug Choice: Cocaine- and Heroin-Taking as a Function of Environmental Context in Humans and Rats

(2009) Daniele Caprioli et al.   BIOLOGICAL PSYCHIATRY

Intermittent Access to 20% Ethanol Induces High Ethanol Consumption in Long-Evans and Wistar Rats

(2008) Jeffrey A. Simms et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Pattern of Intake and Drug Craving Predict the Development of Cocaine Addiction-like Behavior in Rats

(2008) David Belin et al.   BIOLOGICAL PSYCHIATRY

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

(2008) Kelly L. Conrad et al.   NATURE

Behavioral Economic Assessment of Price and Cocaine Consumption Following Self-Administration Histories that Produce Escalation of Either Final Ratios or Intake

(2008) Erik B Oleson et al.   NEUROPSYCHOPHARMACOLOGY

Persistent Alterations in Cognitive Function and Prefrontal Dopamine D2 Receptors Following Extended, but Not Limited, Access to Self-Administered Cocaine

(2008) Lisa A Briand et al.   NEUROPSYCHOPHARMACOLOGY

Controversies in translational research: drug self-administration

(2008) Margaret Haney et al.   PSYCHOPHARMACOLOGY