Article
Clinical Neurology
Shari David, Christian Hohenfeld, Luisa Haberl, Jennifer Pahl, Ana S. Costa, Axel Kilders, Frank Hildebrand, Joerg B. Schulz, Kathrin Reetz, Alexa Haeger
Summary: By comparing three different assessment methods, we found that fitness trackers and physical activity diaries can provide highly comparable estimates of physical activity in individuals with Alzheimer's disease.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Yan Cheng, Edward Zamrini, Charles Faselis, Douglas Redd, Yijun Shao, Charity J. Morgan, Helen M. Sheriff, Ali Ahmed, Peter Kokkinos, Qing Zeng-Treitler
Summary: This study found that cardiorespiratory fitness is associated with the incidence of Alzheimer's disease and related dementias. Moderate and high levels of cardiorespiratory fitness are related to a lower risk of dementia.
ALZHEIMERS & DEMENTIA
(2023)
Article
Sport Sciences
Martin Bahls, Till Ittermann, Ralf Ewert, Beate Stubbe, Henry Voelzke, Nele Friedrich, Stephan B. Felix, Marcus Doerr
Summary: The study suggests that sports and leisure time related physical activity may attenuate the age-related decline in cardiorespiratory fitness, while work-related physical activity was not associated with CRF.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Geriatrics & Gerontology
Sina Gerten, Tobias Engeroff, Johannes Fleckenstein, Eszter Fuezeki, Silke Matura, Ulrich Pilatus, Lutz Vogt, Johannes Pantel, Winfried Banzer
Summary: Participating in physical activity, maintaining physical performance, and reducing sedentary behavior are beneficially associated with cognitive function in older adults. This study found that light physical activity had a positive impact on executive function, while attention and working memory were related to physical performance.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Medicine, General & Internal
Jonathan Myers, Baruch Vainshelboim, Shirit Kamil-Rosenberg, Khin Chan, Peter Kokkinos
Summary: The study found that low cardiorespiratory fitness and physical inactivity are important factors leading to mortality, while increasing cardiorespiratory fitness and promoting physical activity can reduce the risk of death.
MAYO CLINIC PROCEEDINGS
(2021)
Review
Cardiac & Cardiovascular Systems
Peter Kokkinos, Charles Faselis, Labros Sidossis, Jiajia Zhang, Immanuel Babu Henry Samuel, Ali Ahmed, Pamela Karasik, Andreas Pittaras, Michael Doumas, Charalabos Grassos, Shirit Rosenberg, Jonathan Myers
Summary: This study assessed the impact of cardiorespiratory fitness on the association between exercise blood pressure and mortality risk, finding that individuals with low cardiorespiratory fitness had significantly higher mortality risk when SBP-Reserve <_52 mmHg. The risk of mortality was even higher in individuals who were unable to increase their exercise SBP above resting levels.
PROGRESS IN CARDIOVASCULAR DISEASES
(2021)
Article
Pediatrics
Charlie Nezondet, Joseph Gandrieau, Philippe Nguyen, Gautier Zunquin
Summary: This study investigates the relationships between Physical Literacy (PL), body composition, cardiorespiratory fitness, and physical activity levels in French secondary school students. The results show significant associations between PL and percentage of Fat Mass (%FM), moderate to vigorous physical activity (MVPA), Skeletal Muscle Mass (%SMM), and cardiorespiratory fitness. Developing PL in physical activity programs could be beneficial for improving students' activity levels, reducing adiposity, and promoting long-term health.
Article
Clinical Neurology
Michael G. Slee, Stephanie R. Rainey-Smith, Victor L. Villemagne, James D. Doecke, Hamid R. Sohrabi, Kevin Taddei, David Ames, Vincent Dore, Paul Maruff, Simon M. Laws, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, Kirk I. Erickson, Belinda M. Brown
Summary: The study found no significant relationship between habitual physical activity and brain amyloid beta levels in cognitively unimpaired older adults, nor did apolipoprotein E (APOE) ε4 carrier status moderate this relationship.
ALZHEIMERS & DEMENTIA
(2023)
Review
Cardiac & Cardiovascular Systems
Jared M. Gollie, Scott D. Cohen, Samir S. Patel
Summary: Chronic kidney disease is associated with higher cardiovascular disease risk, and incorporating physical activity and exercises into the care of CKD patients is crucial for improving cardiovascular outcomes and fitness.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Sport Sciences
Antonio Garcia-Hermoso, Robinson Ramirez-Velez, Rosa M. Alfonso-Rosa, Borja del Pozo Cruz
Summary: The study showed an inverse association between cardiorespiratory fitness and physical activity levels with white blood cell counts, with active children and adolescents having higher odds of normal white blood cell counts. This suggests that interventions targeting fitness and physical activity could improve the immune system of young individuals.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Sport Sciences
Drazenka Macak, Boris Popovic, Natasa Babic, Cristina Cadenas-Sanchez, Dejan M. Madic, Nebojsa Trajkovic
Summary: The study found that after 6 months of daily physical activity, preschool children showed significant improvements in muscular strength, such as grip strength and sit-ups. However, there were no significant differences between the experimental group and the control group in other fitness components.
JOURNAL OF SPORTS SCIENCES
(2022)
Article
Sport Sciences
Arto Grasten, Mikko Huhtiniemi, Iiris Kolunsarka, Timo Jaakkola
Summary: The study found a positive correlation between the intensity of physical activity and cardiorespiratory fitness in children, while sedentary time was negatively correlated with cardiorespiratory fitness. Girls generally had lower cardiorespiratory fitness and physical activity intensity, while children with higher BMI had lower cardiorespiratory fitness and physical activity intensity.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2022)
Article
Neurosciences
Nicole L. Spartano, Ruiqi Wang, Qiong Yang, Ariel Chernofsky, Joanne M. Murabito, Daniel Levy, Ramachandran S. Vasan, Charles DeCarli, Pauline Maillard, Sudha Seshadri, Alexa S. Beiser
Summary: The study found that cardiometabolic risk factors and epigenetic patterns mediate the association between physical inactivity and unfavorable brain morphology. The findings suggest that cardiometabolic risk factors and epigenetic patterns partially explain the relationship between physical inactivity and lower brain volume, higher white matter diffusivity, and aggregation of free water in the brain.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Environmental Sciences
Diego Augusto Santos Silva, Eliane Cristina de Andrade Goncalves, Emerson Filipino Coelho, Matheus Santos Cerqueira, Francisco Zacaron Werneck
Summary: The aim of this study was to investigate the effect of physical activity levels over 36 months on the cardiorespiratory fitness of children and adolescents. The findings showed that physically active males had a gradual increase in cardiorespiratory fitness throughout the analyzed period, while physically active females had a constant fitness level in the first 24 months and a slight increase after 36 months.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Psychiatry
Jeroen Deenik, Lisanne E. M. Koomen, Thomas W. Scheewe, Frank P. van Deursen, Wiepke Cahn
Summary: This study found that the physical activity behavior and attitude of physicians/clinicians in mental healthcare can impact the referral of patients to physical activity interventions. HCP who had personal experience with physical activity were more likely to refer patients.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Geriatrics & Gerontology
Mona Michelet, Geir Selbaek, Bjorn Heine Strand, Anne Lund, Knut Engedal, Anja Bieber, Manuel Goncalves-Pereira, Louise Hopper, Kate Irving, Hannah Jelley, Maria J. Marques, Martin Orrell, Daniel M. Portolani, Britt-Marie Sjolund, Anders Skoldunger, Astrid Stephan, Frans Verhey, Marjolein de Vugt, Claire Wolfs, Bob Woods, Orazio Zanetti, Sverre Bergh
Summary: The study found that unmet needs for daytime activities and company were closely associated with affective and psychotic symptoms in dementia patients, indicating that reducing these unmet needs could help alleviate symptoms in dementia patients.
AGING & MENTAL HEALTH
(2022)
Article
Geriatrics & Gerontology
Ben Kamsvaag, Sverre Bergh, Jurate Saltyte Benth, Geir Selbaek, Kjerstin Tevik, Anne-Sofie Helvik
Summary: The study found that alcohol consumption among older Norwegian adults with symptoms of cognitive decline was higher than the national average, and demonstrated that next of kin can be a reliable source of information regarding older adults' alcohol consumption. Healthcare professionals should take these findings into consideration when assessing and developing interventions for older adults.
AGING & MENTAL HEALTH
(2022)
Article
Geriatrics & Gerontology
Anne-Sofie Helvik, Sverre Bergh, Jurate Saltyte Benth, Geir Selbaek, Bettina S. Husebo, Kjerstin Tevik
Summary: The study aimed to describe pain, use of analgesics, and quality of life in Norwegian nursing home residents with dementia, and to explore the association between pain and quality of life. Results showed that 36% of participants had clinically relevant pain intensity, 52% received analgesics, and more severe pain was associated with poorer quality of life.
AGING & MENTAL HEALTH
(2022)
Article
Geriatrics & Gerontology
Tom Borza, Magnus Harneshaug, Lene Kirkhus, Jurate Saltyte Benth, Geir Selbaek, Sverre Bergh, Marit Slaaen
Summary: The study showed that more severe depressive symptoms, measured by the GDS-15, were associated with higher mortality in older patients with cancer. The symptoms on the GDS-15 increased during the first four months of the study, with 'prefer to stay at home' being the most prevalent and persistent, while 'not to be in good spirits most of the time' being the least prevalent.
AGING & MENTAL HEALTH
(2022)
Article
Geriatrics & Gerontology
Maria J. Marques, Eva Y. L. Tan, Bob Woods, Hannah Jelley, Liselot Kerpershoek, Louise Hopper, Kate Irving, Anja Bieber, Astrid Stephan, Anders Skoldunger, Britt-Marie Sjolund, Geir Selbaek, Janne Rosvik, Orazio Zanetti, Daniel M. Portolani, Joao Maroco, Marjolein de Vugt, Frans Verhey, Manuel Goncalves-Pereira
Summary: The study found that higher stress levels among carers were associated with lower RQ ratings, while a sense of coherence and being a spouse were linked to more positive RQ assessments. Increased neuropsychiatric symptoms in dementia patients were related to a decline in carers' RQ, whereas social support was associated with more positive RQ trajectories.
AGING & MENTAL HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Margit Gausdal Strandenaes, Anne Lund, Knut Engedal, Oyvind Kirkevold, Geir Selbaek, Jurate Saltyte Benth, Anne Marie Mork Rokstad
Summary: The study aimed to compare self-reported Quality of Life in people with dementia attending day care with those who did not, and explore factors associated with QoL. Participants in day care reported higher QoL scores than those who did not attend, indicating a positive impact of day care on the lives of people with dementia.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Article
Neurosciences
Jelena Zugic Soares, Jorgen Valeur, Jurate Saltyte Benth, Anne-Brita Knapskog, Geir Selbaek, Golchin Arefi, D. Gregor Gilfillan, Anita Tollisen, Nenad Bogdanovic, Renate Pettersen
Summary: This study found that patients with positive biomarkers of Alzheimer's disease have lower levels of vitamin D in their cerebrospinal fluid (CSF), despite sufficient levels in their serum. Moreover, certain gene polymorphisms are associated with a decline in cognitive ability.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Neurosciences
Knut Engedal, Linda Gjora, Jurate Saltyte Benth, Jorgen Wagle, Thale Kinne Ronqvist, Geir Selbaek
Summary: This study aimed to determine normative scores on the Montreal Cognitive Assessment Scale (MoCA) for Norwegian older adults stratified by educational level, age, and sex. The results showed that normative scores on the MoCA varied between different groups, and education, age, and sex were significant predictors of scores.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Sport Sciences
Ekaterina Zotcheva, Asta Kristine Haberg, Ulrik Wisloff, Oyvind Salvesen, Geir Selbaek, Dorthe Stensvold, Linda Ernstsen
Summary: The study aimed to investigate the association between a 5-year exercise intervention and change in peak oxygen uptake with cognitive function in older adults. Overall, exercise was not significantly associated with cognition among older adults. However, maintaining or increasing VO2peak appeared to benefit cognition.
Article
Pharmacology & Pharmacy
Enrico Callegari, Jurate Saltyte Benth, Geir Selbaek, Cato Gronnerod, Sverre Bergh
Summary: This study aimed to test the effect of NorGeP-NH criteria on clinical outcomes in nursing home residents. The results showed that NorGeP-NH did not have a significant impact on quality of life and medication prescriptions, but it was able to reduce depression scores.
Article
Health Care Sciences & Services
Kari-Anne Hoel, Bjorn Lichtwarck, Anette Vaeringstad, Ingvild Hjorth Feiring, Anne Marie Mork Rokstad, Geir Selbaek, Jurate Saltyte Benth, Sverre Bergh
Summary: The study found that home care staff generally considered TIME to be an appropriate method for managing BPSD in dementia patients, especially the systematic approach to symptom management. However, the completion of the assessment phase was seen as exhaustive and time-consuming, and some staff found it challenging to allocate time for case conferences. The feasibility trial suggests that TIME could be beneficial with some adjustments for staff in home care services facing challenges in providing care for people with dementia.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Gerontology
Vegard Skirbekk, Catherine E. Bowen, Asta Haberg, Astanand Jugessur, Bo Engdahl, Bernt Bratsberg, Ekaterina Zotcheva, Geir Selbaek, Hans-Peter Kohler, Jordan Weiss, Jennifer R. Harris, Sarah E. Tom, Steinar Krokstad, Yaakov Stern, Bjorn Heine Strand
Summary: This study investigates the association between midlife marital status trajectories and the risk of dementia and mild cognitive impairment (MCI) in old age. The results suggest that staying married in midlife is associated with a lower risk of dementia, while being single or divorced increases the risk. The findings highlight the importance of marital status on cognitive health. Rating: 8/10.
JOURNAL OF AGING AND HEALTH
(2023)
Article
Biochemical Research Methods
Katrine Sjaastad Hanssen, Menno P. Witter, Axel Sandvig, Ioanna Sandvig, Asgeir Kobro-Flatmoen
Summary: Primary neuronal cultures are commonly used to study Alzheimer's disease, but usually lack neuron specificity. This study presents a method for dissecting and culturing adult lateral entorhinal layer II-neurons from AD-model mice. The results show that these neurons maintain electrophysiological activity during long-term culture, providing a platform for studying AD pathological changes.
JOURNAL OF NEUROSCIENCE METHODS
(2023)
Article
Public, Environmental & Occupational Health
G. Kjelvik, G. Selbaek, A. M. M. Rokstad
Summary: This study aimed to explore the knowledge and motivation for adopting recommended health behaviours among older adults in Norway. Through individual interviews, it was found that older adults have some knowledge and motivation for reducing the risk of dementia, and various factors influence their willingness for prevention, including healthy diet, physical, social, and cognitive activities. Therefore, understanding the motivating factors of older adults is essential in developing preventive interventions, and promoting healthy aging is important.
Article
Health Care Sciences & Services
Ekaterina Zotcheva, Bernt Bratsberg, Bjorn Heine Strand, Astanand Jugessur, Bo Lars Engdahl, Catherine Bowen, Geir Selbaek, Hans-Peter Kohler, Jennifer R. Harris, Jordan Weiss, Sarah E. Tom, Steinar Krokstad, Teferi Mekonnen, Trine Holt Edwin, Yaakov Stern, Asta Kristine Haberg, Vegard Skirbekka
Summary: Consistently working in an occupation with intermediate or high occupational physical activity is associated with an increased risk of cognitive impairment, indicating the importance of developing strategies for individuals in physically demanding occupations to prevent cognitive impairment.
LANCET REGIONAL HEALTH-EUROPE
(2023)