The structure of the catalytic domain of the ATP synthase fromMycobacterium smegmatisis a target for developing antitubercular drugs

The NMR solution structure of Mycobacterium tuberculosis F-ATP synthase subunit ε provides new insight into energy coupling inside the rotary engine

(2018) Shin Joon et al.   FEBS Journal

Structure, mechanism, and regulation of the chloroplast ATP synthase

(2018) Alexander Hahn et al.   SCIENCE

Structure of the γ–ε complex of cyanobacterial F1-ATPase reveals a suppression mechanism of the γ subunit on ATP hydrolysis in phototrophs

(2018) Satoshi Murakami et al.   BIOCHEMICAL JOURNAL

Revisiting the timetable of tuberculosis

(2018) Marcel A Behr et al.   BMJ-British Medical Journal

The uniqueness of subunit α of mycobacterial F-ATP synthases: An evolutionary variant for niche adaptation

(2017) Priya Ragunathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bedaquiline Targets the ε Subunit of Mycobacterial F-ATP Synthase

(2016) Subhashri Kundu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Regulation of the thermoalkaliphilic F1-ATPase fromCaldalkalibacillus thermarum

(2016) Scott A. Ferguson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling

(2016) Rein M. G. J. Houben et al.   PLOS MEDICINE

Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states

(2016) Meghna Sobti et al.   eLife

Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis

(2015) Rokeya Tasneen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure of a thermophilic F1-ATPase inhibited by an ε-subunit: deeper insight into the ε-inhibition mechanism

(2015) Yasuo Shirakihara et al.   FEBS Journal

How release of phosphate from mammalian F1-ATPase generates a rotary substep

(2015) John V. Bason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of ATP synthase fromParacoccus denitrificansdetermined by X-ray crystallography at 4.0 Å resolution

(2015) Edgar Morales-Rios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the mycobacterial ATP synthase Fo rotor ring in complex with the anti-TB drug bedaquiline

(2015) L. Preiss et al.   Science Advances

Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis

(2014) Rokeya Tasneen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multidrug-Resistant Tuberculosis and Culture Conversion with Bedaquiline

(2014) Andreas H. Diacon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase

(2014) J. V. Bason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin processivity is gated by phosphate release

(2014) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trapping the ATP binding state leads to a detailed understanding of the F1-ATPase mechanism

(2014) Kwangho Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Timing of inorganic phosphate release modulates the catalytic activity of ATP-driven rotary motor protein

(2014) Rikiya Watanabe et al.   Nature Communications

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

(2014) Anil Koul et al.   Nature Communications

F1-ATPase ofEscherichia coli

(2013) Naman B. Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

Phosphate release coupled to rotary motion of F1-ATPase

(2013) K.-i. Okazaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1

(2013) G. C. Robinson et al.   Open Biology

Randomized Pilot Trial of Eight Weeks of Bedaquiline (TMC207) Treatment for Multidrug-Resistant Tuberculosis: Long-Term Outcome, Tolerability, and Effect on Emergence of Drug Resistance

(2012) A. H. Diacon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Solution structure of subunit γ (γ1-204) of the Mycobacterium tuberculosis F-ATP synthase and the unique loop of γ165-178, representing a novel TB drug target

(2012) Ragunathan Priya et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F1-ATPase from bovine heart mitochondria

(2012) D. M. Rees et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Function Relationships of the G Domain, a Canonical Switch Motif

(2011) Alfred Wittinghofer et al.   Annual Review of Biochemistry

Structure of the ATP synthase catalytic complex (F1) from Escherichia coli in an autoinhibited conformation

(2011) Gino Cingolani et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATP synthase in slow- and fast-growing mycobacteria is active in ATP synthesis and blocked in ATP hydrolysis direction

(2010) Anna C. Haagsma et al.   FEMS MICROBIOLOGY LETTERS

Phosphate release in F1-ATPase catalytic cycle follows ADP release

(2010) Rikiya Watanabe et al.   Nature Chemical Biology

Unique Flexibility in Energy Metabolism Allows Mycobacteria to Combat Starvation and Hypoxia

(2010) Michael Berney et al.   PLoS One

A novel 11-kDa inhibitory subunit in the F1FO ATP synthase of Paracoccus denitrificans and related α-proteobacteria

(2009) Edgar Morales-Ríos et al.   FASEB JOURNAL

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

(2008) S. P. S. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA