ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation

Epithelial Mesenchymal Transition in Tumor Metastasis

(2018) Vivek Mittal   Annual Review of Pathology-Mechanisms of Disease

Re-evaluating the role of FOXOs in cancer

(2018) M. Hornsveld et al.   SEMINARS IN CANCER BIOLOGY

The Evolutionary Landscape of Dbl-Like RhoGEF Families: Adapting Eukaryotic Cells to Environmental Signals

(2017) Philippe Fort et al.   Genome Biology and Evolution

Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis

(2017) Lei Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

(2017) Xiangjun Kong et al.   NATURE

Comparison of three different methods for the detection of circulating tumor cells in mice with lung metastasis

(2017) Weifeng Xu et al.   ONCOLOGY REPORTS

In Vivo Visualization and Characterization of Epithelial–Mesenchymal Transition in Breast Tumors

(2016) Zhen Zhao et al.   CANCER RESEARCH

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Epithelial–mesenchymal transition (EMT) and metastasis: yes, no, maybe?

(2016) Maren Diepenbruck et al.   CURRENT OPINION IN CELL BIOLOGY

Regulating Rho GTPases and their regulators

(2016) Richard G. Hodge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

14-3-3ζ Turns TGF-β’s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2

(2015) Jia Xu et al.   CANCER CELL

ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

(2015) Peijing Zhang et al.   CELL CYCLE

An epigenetically distinct breast cancer cell subpopulation promotes collective invasion

(2015) Jill M. Westcott et al.   JOURNAL OF CLINICAL INVESTIGATION

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Dock-family exchange factors in cell migration and disease

(2014) Gilles Gadea et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer

(2014) Cunxi Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

(2013) Julie Caramel et al.   CANCER CELL

Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells

(2013) Wai Leong Tam et al.   CANCER CELL

FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress

(2013) Bhaskar Ponugoti et al.   JOURNAL OF CELL BIOLOGY

ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines

(2013) S. Radtke et al.   JOURNAL OF CELL SCIENCE

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Glycogen synthase kinase-3β positively regulates protein synthesis and cell proliferation through the regulation of translation initiation factor 4E-binding protein 1

(2013) S Shin et al.   ONCOGENE

Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis

(2013) X. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

(2013) M. A. Nieto   SCIENCE

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

(2012) Stephan P Tenbaum et al.   NATURE MEDICINE

High ERK Protein Expression Levels Correlate with Shorter Survival in Triple-Negative Breast Cancer Patients

(2012) C. Bartholomeusz et al.   ONCOLOGIST

Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think: Table I.

(2011) Camille Lobry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Partners in crime: the TGFβ and MAPK pathways in cancer progression

(2011) Douglas A Chapnick et al.   Cell and Bioscience

The dynamic roles of TGF-β in cancer

(2010) Erik Meulmeester et al.   JOURNAL OF PATHOLOGY

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

(2010) Sejeong Shin et al.   MOLECULAR CELL

Discovery of Novel Forkhead Box O1 Inhibitors for Treating Type 2 Diabetes: Improvement of Fasting Glycemia in Diabetic db/db Mice

(2010) T. Nagashima et al.   MOLECULAR PHARMACOLOGY

FOXO3a Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases

(2009) P. Storz et al.   MOLECULAR AND CELLULAR BIOLOGY

BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases

(2009) M J Hoenerhoff et al.   ONCOGENE

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

(2008) Michael D Oberst et al.   BMC CANCER

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

Unravelling the tumor-suppressive functions of FOXO proteins

(2008) Tobias B. Dansen et al.   TRENDS IN CELL BIOLOGY