Quadruplex-forming oligonucleotide targeted to the VEGF promoter inhibits growth of non-small cell lung cancer cells

Homologous PNA Hybridization to Noncanonical DNA G-Quadruplexes

(2016) Karen A. Kormuth et al.   BIOCHEMISTRY

RNA G-Quadruplex Invasion and Translation Inhibition by Antisense γ-Peptide Nucleic Acid Oligomers

(2016) Stanley N. Oyaghire et al.   BIOCHEMISTRY

Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

(2016) Sylvain Geny et al.   NUCLEIC ACIDS RESEARCH

Discovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression

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Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer

(2015) Martin P Barr et al.   Molecular Cancer

Hybridization of G-Quadruplex-Forming Peptide Nucleic Acids to Guanine-Rich DNA Templates Inhibits DNA Polymerase η Extension

(2014) Connor T. Murphy et al.   BIOCHEMISTRY

c-Myc Quadruplex-forming Sequence Pu-27 Induces Extensive Damage in Both Telomeric and Nontelomeric Regions of DNA

(2014) Md Ashraful Islam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Improved Model for the hTERT Promoter Quadruplex

(2014) Jonathan B. Chaires et al.   PLoS One

CK2 inhibitor CX4945 induces sequential inactivation of proteins in the signaling pathways related with cell migration and suppresses metastasis of A549 human lung cancer cells

(2013) Min Jeong Ku et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

High circulating VEGF level predicts poor overall survival in lung cancer

(2013) Pingping Hu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

Highly Recurrent TERT Promoter Mutations in Human Melanoma

(2013) F. W. Huang et al.   SCIENCE

Expression, prognostic and predictive impact of VEGF and bFGF in non-small cell lung cancer

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The β-Carboline Alkaloid Harmol Induces Cell Death via Autophagy but Not Apoptosis in Human Non-small Cell Lung Cancer A549 Cells

(2011) Akihisa Abe et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Genomic c-Myc Quadruplex DNA Selectively Kills Leukemia

(2011) K. C. Sedoris et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia induces differential translation of enolase/MBP-1

(2010) Kara C Sedoris et al.   BMC CANCER

Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway

(2010) Yi-Chieh Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Intracellular Traffic of Oligodeoxynucleotides In and Out of the Nucleus: Effect of Exportins and DNA Structure

(2010) Stephen J. Forsha et al.   OLIGONUCLEOTIDES

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Myricetin Suppresses Invasion and Migration of Human Lung Adenocarcinoma A549 Cells: Possible Mediation by Blocking the ERK Signaling Pathway

(2009) Yuan-Wei Shih et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Formation of a Unique End-to-End Stacked Pair of G-Quadruplexes in the hTERT Core Promoter with Implications for Inhibition of Telomerase by G-Quadruplex-Interactive Ligands

(2009) SunMi L. Palumbo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acyclic retinoid inhibits angiogenesis by suppressing the MAPK pathway

(2009) Yusuke Komi et al.   LABORATORY INVESTIGATION

Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides

(2009) Enid W. Choi et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

(2008) Michael Degtyarev et al.   JOURNAL OF CELL BIOLOGY

The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents

(2008) D. Sun et al.   MOLECULAR CANCER THERAPEUTICS