Mesenchymal stem cells inhibit T-cell function through conserved induction of cellular stress

Immune modulation by apoptotic dental pulp stem cells in vivo

(2018) Adam G Laing et al.   Immunotherapy

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation

(2017) Antonio Galleu et al.   Science Translational Medicine

Activation of Gcn2 in response to different stresses

(2017) Silje Anda et al.   PLoS One

Clinical Trials with Mesenchymal Stem Cells: An Update

(2016) Tiziana Squillaro et al.   CELL TRANSPLANTATION

Stress Kinase GCN2 Controls the Proliferative Fitness and Trafficking of Cytotoxic T Cells Independent of Environmental Amino Acid Sensing

(2016) Lee-Ann Van de Velde et al.   Cell Reports

Regulation of T cells by mTOR: the known knowns and the known unknowns

(2015) Kristen N. Pollizzi et al.   TRENDS IN IMMUNOLOGY

Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4

(2013) Rikke B. Holmgaard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

(2012) Peter Connick et al.   LANCET NEUROLOGY

Ligation of TLR2 and TLR4 on murine bone marrow-derived mesenchymal stem cells triggers differential effects on their immunosuppressive activity

(2011) Junxia Lei et al.   CELLULAR IMMUNOLOGY

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

(2011) R. Ciccocioppo et al.   GUT

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

(2011) Yi Liu et al.   NATURE MEDICINE

Mesenchymal stem cell effects on T-cell effector pathways

(2011) Michelle M Duffy et al.   Stem Cell Research & Therapy

The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism

(2010) Jonathan D. Powell et al.   IMMUNITY

Placenta-derived MSCs are partially immunogenic and less immunomodulatory than bone marrow-derived MSCs

(2010) H. Fazekasova et al.   Journal of Tissue Engineering and Regenerative Medicine

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

Immunomodulatory Function of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Autoimmune Type 1 Diabetes

(2009) P. Fiorina et al.   JOURNAL OF IMMUNOLOGY

Identification of a Novel Amino Acid Response Pathway Triggering ATF2 Phosphorylation in Mammals

(2009) C. Chaveroux et al.   MOLECULAR AND CELLULAR BIOLOGY

Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression

(2009) Guangwen Ren et al.   STEM CELLS

Requirement of IFN-γ–Mediated Indoleamine 2,3-Dioxygenase Expression in the Modulation of Lymphocyte Proliferation by Human Adipose–Derived Stem Cells

(2009) Olga DelaRosa et al.   TISSUE ENGINEERING PART A

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

(2008) Uwe M. Fischer et al.   STEM CELLS AND DEVELOPMENT

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

(2007) Francesco Liotta et al.   STEM CELLS