Article
Plant Sciences
Xiaoyan Zhang, Mengjia Zhang, Tingting Zhao, Bo Deng
Summary: Cyclocarya paliurus accumulates flavonoids dependent on phosphate availability, with low Pi resulting in increased surplus carbon allocated to N-metabolism and carbohydrate synthesis, leading to higher levels of enzymatic activities and flavonoid accumulation in leaves. Growth and biomass accumulation are increased under elevated Pi levels, while the highest flavonoid yield per plant is obtained under relative low Pi conditions, providing insights for maintaining high yield and quality of medicinal plants and crops.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Food Science & Technology
Li-Hua Zhu, Ying-Yin Xu, Li-ping Zhu, Xian Zheng, Cui-Hua Jiang, Jian-Jing Liu, Jian Zhang, Zhi-Qi Yin
Summary: The aqueous extract of Cyclocarya paliurus (CPA) shows significant therapeutic effects on hyperuricemia (HUA) and renal inflammation, possibly achieved by blocking the ROS/NLRP3/IL-1 beta pathway.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Forestry
Jian Qin, Xiliang Yue, Shengzuo Fang, Mengyu Qian, Shuntao Zhou, Xulan Shang, Wanxia Yang
Summary: Nitrogen fertilization significantly affects the growth, nitrogen metabolism, and photosynthesis parameters of Cyclocarya paliurus, increasing leaf nitrogen content and NDFF while decreasing nitrogen use efficiency. Leaf C:N:P stoichiometry is more strongly related to plantation growth and can be used as an indicator for key nutrient availability in the soil.
FOREST ECOLOGY AND MANAGEMENT
(2021)
Article
Forestry
Caowen Sun, Xulan Shang, Haifen Ding, Yanni Cao, Shengzuo Fang
Summary: Cyclocarya paliurus, widely distributed in subtropical areas of China, contains flavonoids and triterpenoids in its leaves which provide protection against diseases. The study found that altitude, latitude, and longitude significantly contributed to variations in total flavonoid and triterpenoid contents. The interaction of these metabolites was extensively correlated with environment changes, suggesting they should be considered during selection and cultivation.
JOURNAL OF FORESTRY RESEARCH
(2021)
Article
Forestry
Yang Liu, Pei Chen, Shuhui Chen, Ziying Hang, Songheng Jin
Summary: This study investigated the effects of nitrogen (N) addition with different organic nitrogen (ON) to inorganic nitrogen (IN) ratios on the growth and stoichiometric characteristics of Cyclocarya paliurus. The results showed that N addition with different ON:IN ratios led to a decrease in growth rate and biomass accumulation, while leaf phenolic content showed an opposite trend to leaf stoichiometry. These findings indicate that N addition caused stoichiometric imbalance and altered plant growth and accumulation of secondary metabolism substances. Consideration of nutrient limitation type and variation in N deposition components is necessary to predict the future responses of plant functional traits to N deposition.
FOREST ECOLOGY AND MANAGEMENT
(2023)
Article
Plant Sciences
Caowen Sun, Shengzuo Fang, Xulan Shang
Summary: The leaves of Cyclocarya paliurus contain abundant flavonoids with beneficial bioactivities and antioxidant activities. Through the study of the flavonoid variation mechanism in red leaves, it was found that red leaves have higher anthocyanin and quercetin content, while lower kaempferol and catechins content compared to green leaves. Flavonoid biosynthesis-related genes and transcription factors were also identified. These findings provide useful information for the selection and breeding of Cyclocarya paliurus.
ACTA PHYSIOLOGIAE PLANTARUM
(2023)
Article
Biochemistry & Molecular Biology
Jin Yan, Sichen He, Lingli Chen, Hui Chen, Wenjun Wang
Summary: The addition of Cyclocarya paliurus flavonoids (CPF) enhanced the functional properties of gelatin-chitosan (GEL-CS) composite films, making them exhibit superior antioxidant and antimicrobial properties, as well as environmentally friendly and edible features, providing a potential packaging material for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Zheling Feng, Zhujun Fang, Cheng Chen, Chi Teng Vong, Jiali Chen, Ruohan Lou, Maggie Pui Man Hoi, Lishe Gan, Ligen Lin
Summary: This study identified polysaccharides and flavonoids as the key components responsible for the anti-hyperglycemic effect of Cyclocarya paliurus leaves, which work by enhancing insulin secretion and improving diabetic complications. Further refinement of the clinical application of Cyclocarya paliurus is needed based on these findings.
Article
Forestry
Tingting Zhao, Bangyou Yu, Mengjia Zhang, Shuying Chen, Bo Deng
Summary: This study found that inoculating with mycorrhizal fungi has a significant positive effect on the growth and production of secondary metabolites in Cyclocarya paliurus. Inoculation with the fungi enhances plant growth, biomass accumulation, and yield of health-promoting substances, while also triggering a systemic defense response.
Article
Biochemistry & Molecular Biology
Meng-Zhao, Yi-Han, Jing'en Li, Qi-An, Ximei Ye, Xiang-Li, Zitong Zhao, Yang-Zhang, Jing-He, Qihuan Deng, Wenjun Wang
Summary: This study investigated the primary structure and protective effect of an acetylated Cyclocarya paliurus polysaccharide (Ac-CPP0.1) on dendritic cells treated with H2O2. Ac-CPP0.1 was found to enhance antioxidant enzyme levels, modulate Nrf2 and Keap1 expression, and exhibit better antioxidant capacity compared to CPP0.1.Results suggest the potential application of Ac-CPP0.1 as an antioxidant agent.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Yao Liu, Guan-Tao Zheng, Xuan-Xuan Zhang, Xian-Tao Zhang, Xu-Lan Shang, Sheng-Zuo Fang, Jian Zhang, Zhi-Qi Yin
Summary: Two new triterpenoids and thirteen known compounds were isolated from the leaves of Cyclocarya paliurus. These compounds were evaluated for their therapeutic effects on fibrosis induced by diabetic nephropathy, with compounds 3, 5, and 8 showing significant inhibition rates.
NATURAL PRODUCT RESEARCH
(2022)
Article
Plant Sciences
Mengjia Zhang, Bangyou Yu, Xiaoyan Zhang, Bo Deng
Summary: Inhibition of nitrogen assimilation in callus of Cyclocarya paliurus led to down-regulated primary metabolisms and disrupted growth, while inducing the biosynthesis of flavonoids and triterpenoids, antioxidase system, and SnRK2-mediated ABA and JA signaling.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yao Liu, Xuan-Xuan Zhang, Su-Su Xu, Si-Yang Fang, Li-Pang Zhu, Zhe Song, Xu-Lan Shang, Sheng-Zuo Fang, Ke Pan, Xiao-Long Cao, Zhi-Qi Yin
Summary: A study on Cyclocarya paliurus, a Chinese herbal medicine, discovered new compounds with anti-fibrotic activities. Compound 16 showed significant inhibition of fibronectin levels and alleviated the epithelial-mesenchymal transformation (EMT) process. These findings provide potential drug candidates for the prevention of diabetic nephropathy.
Article
Food Science & Technology
Yu-Yan Wang, Shi-Juan Lu, Rui Gui, Jian-Ping Wu, Jing Li, Xiao-Ai He, Wei Zhang, Gui-Ming Deng, Wen-Xuan Wang, Hong-Ping Long, Xi-Fan Wei, Guang-Yao Zeng, Na Zhang, Shu-Min Zang, Ye Yao, Zu-Hui Chen, Cheng Fei, Yi-Kun Wang, Kang-Ping Xu
Summary: In this study, the efficacy and related mechanisms of Cyclocarya paliurus flavonoids (CPF) in preventing non-alcoholic steatohepatitis (NASH) were investigated using lipidomics and proteomics. CPF supplementation significantly reduced body and liver weight gain, cholesterol and triacylglycerols (TGs) levels in NASH mice, and improved hepatic steatosis by reducing liver inflammation score and the area of liver fibrosis. Lipidomics analysis showed that the prevention of NASH by CPF was closely associated with the decrease in levels of TGs, diacylglycerols (DGs), and ceramides (Cers). Proteomics analysis revealed that CPF promoted metabolic homeostasis in the liver. The study concluded that the remodulation of lipid homeostasis may be a pivotal pathway for the potential mechanisms of CPF in protecting against NASH.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Pharmacology & Pharmacy
Jinggang Mo, Yingpeng Tong, Junxia Ma, Kunpeng Wang, Yifu Feng, Liezhi Wang, Hao Jiang, Chong Jin, Junmin Li
Summary: In this study, the effect of Cyclocarya paliurus total flavonoids (CTFs) extract on apoptosis mechanisms in HepG2 cells was tested through in vitro cell culture experiments. Network pharmacology was applied to explore the effects of CTFs on liver cancer and its potential mechanisms. Additionally, the effect of 3-hydroxyflavone and luteolin on inducing apoptosis and inhibiting the proliferation of HepG2 cells was verified.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Plant Sciences
Wanli You, Jinglin Zhang, Xueyin Ru, Feng Xu, Zhengguo Wu, Peng Jin, Yonghua Zheng, Shifeng Cao
Summary: This study investigated the effect of calcium chloride (CaCl2) treatment on GABA accumulation in fresh-cut cantaloupe and the underlying mechanisms. The results showed that CaCl2 treatment increased GABA content and the activities of GAD and SSADH enzymes, while reducing glutamate content and GABA-T activity. Additionally, CaCl2 treatment upregulated the expressions of CmCML11 and CmCAMTA5, as well as several GABA shunt genes, through the transcriptional activation by CmCAMTA5. Furthermore, the interaction between CmCML11 and CmCAMTA5 enhanced the transcriptional activation of GABA shunt genes. Overall, this study reveals that CaCl2 treatment promotes GABA accumulation in fresh-cut cantaloupe through the combined effect of CmCML11 and CmCAMTA5 in regulating the expressions of GABA shunt genes.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Min Wang, Yupeng Wang, Xiaohui Wang, Guangwei Wei, Huiyi Yang, Xi Yang, Tinghai Shen, Huijie Qu, Sheng Fang, Ziming Wu
Summary: This study identified the high nitrogen use efficiency (NUE) black sesame variety 17-156 and analyzed its underlying physiological and molecular mechanisms. The results showed that 17-156 possesses a sophisticated nitrogen metabolizing machinery to uptake and assimilate higher quantities of inorganic nitrogen, simultaneously improving carbon metabolism and growth. Many important genes were up-regulated in 17-156 under high nitrogen condition. Additionally, 38 potential candidate genes were identified for future studies to improve sesame's NUE. These findings provide valuable resources for understanding the regulatory network of nitrogen metabolism and developing sesame cultivars with improved NUE.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
He Dong, Chongmei Xu, Chengtao Zhang, Li Zhang, Yaqin Yao, Suiqi Zhang
Summary: The study found that short cells in maize leaves not only improve leaf mechanical support and photosynthetic performance, enhance drought resistance, but also participate in stomatal regulation.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Na Liu, Wenyan Shang, Mengxin Guan, Jibin Xiao, Guangxiang Tian, Baozhan Ma, Wenjing Shang, Xu Li, Shijia Zhao, Chuang Li, Kun Cheng, Wenming Zheng
Summary: This study cloned the full-length cDNA sequence of TaSPX3 gene in wheat and found that TaSPX3 responds to low phosphorus stress in multiple wheat genotypes. Overexpressing TaSPX3 can alleviate phosphorus deficiency symptoms and promote plant growth in Arabidopsis. The study also revealed the interaction of TaSPX3 with other genes related to the phosphorus starvation signaling pathway.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Kongyuan Wu, Lizhen Wang, Zihan Wu, Ziqing Liu, Zengfei Li, Jun Shen, Shengjie Shi, Hong Liu, Christopher Rensing, Renwei Feng
Summary: Selenium (Se) can reduce uptake and translocation of cadmium (Cd) in plants by regulating root morphology. This study investigated the effects of Se(IV) on root exudates, root morphology, root endogenous hormones, and Cd uptake efficiency in rice under Cd stress. The results showed that Se(IV) significantly reduced Cd concentrations in shoots and roots, and decreased Cd uptake efficiency via root hairs. Se(IV) also affected root morphology, root exudates, and the synthesis of hormones like IAA and JA. However, transcriptome analysis revealed no upregulated differentially expressed genes (DEGs) in IAA synthesis.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Di Wang, Huaifang Zhang, Xuefei Hu, Haizhen Zhang, Shuang Feng, Aimin Zhou
Summary: This study identified a cell number regulator gene called SlCNR8 in willow, which enhances resistance to trace metals in transgenic poplar seedlings. SlCNR8 reduces Cd uptake and accumulation, and can be used as a candidate gene for genetic improvement of phytostabilisation of trace metals.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
