Hyperosmotic Stress Initiates AMPK-Independent Autophagy and AMPK- and Autophagy-Independent Depletion of Thioredoxin 1 and Glyoxalase 2 in HT22 Nerve Cells

Biological Production, Detection, and Fate of Hydrogen Peroxide

(2018) Christine C. Winterbourn   ANTIOXIDANTS & REDOX SIGNALING

AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2

(2018) Chloé Philippe et al.   NEOPLASIA

So many roads: the multi-faceted regulation of autophagy induction

(2018) Angel F. Corona Velazquez et al.   MOLECULAR AND CELLULAR BIOLOGY

Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells

(2017) Alcir Luiz Dafre et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modulation of signaling mechanisms in the heart by thioredoxin 1

(2017) Narayani Nagarajan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage

(2017) Cecilia Nigro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress

(2017) Katherine L. Schutt et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems

(2017) Ariana Ern Schmitz et al.   NEUROTOXICITY RESEARCH

Disturbances of thirst and fluid balance associated with aging

(2017) Denovan P. Begg   PHYSIOLOGY & BEHAVIOR

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

(2017) Rhianna C. Laker et al.   Nature Communications

Hyperosmotic stress stimulates autophagy via polycystin-2

(2017) Daniel Peña-Oyarzun et al.   Oncotarget

Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus

(2017) Chao Liu et al.   Scientific Reports

On the Relationship between Energy Metabolism, Proteostasis, Aging and Parkinson’s Disease: Possible Causative Role of Methylglyoxal and Alleviative Potential of Carnosine

(2017) Alan R. Hipkiss   Aging and Disease

Compound C inhibits macrophage chemotaxis through an AMPK-independent mechanism

(2016) Youngyi Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments

(2016) N. Rabbani et al.   CLINICAL SCIENCE

Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies

(2016) Yousif A. Shamsaldeen et al.   CURRENT DRUG METABOLISM

Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages

(2016) Elizabeth Liu et al.   INFECTION AND IMMUNITY

Hyperosmotic Stress Induces Tau Proteolysis by Caspase-3 Activation in SH-SY5Y Cells

(2016) Marta Olivera-Santa Catalina et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Compound C induces the ramification of murine microglia in an AMPK-independent and small rhogtpase-dependent manner

(2016) C. Huang et al.   NEUROSCIENCE

Activation of autophagy via Ca2+-dependent AMPK/mTOR pathway in rat notochordal cells is a cellular adaptation under hyperosmotic stress

(2015) Li-Bo Jiang et al.   CELL CYCLE

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

(2015) Weili Tian et al.   FEBS LETTERS

Methylglyoxal, the foe and friend of glyoxalase and Trx/TrxR systems in HT22 nerve cells

(2015) A.L. Dafre et al.   FREE RADICAL BIOLOGY AND MEDICINE

Physiology of the Alzheimer’s disease

(2015) Jung Y. Hahr   MEDICAL HYPOTHESES

AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells

(2014) Brice Sid et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of autophagy: Modulation of the size and number of autophagosomes

(2014) Meiyan Jin et al.   FEBS LETTERS

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

(2014) X. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Signaling via a peroxiredoxin sensor

(2014) Christine C Winterbourn et al.   Nature Chemical Biology

Role of Methylglyoxal in Alzheimer’s Disease

(2014) Cristina Angeloni et al.   Biomed Research International

Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters

(2013) Paula Nunes et al.   Autophagy

Concurrent regulation of the transcription factors Nrf2 and ATF4 mediates the enhancement of glutathione levels by the flavonoid fisetin

(2013) Jennifer L. Ehren et al.   BIOCHEMICAL PHARMACOLOGY

Tat-glyoxalase protein inhibits against ischemic neuronal cell damage and ameliorates ischemic injury

(2013) Min Jea Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Response to Hyperosmotic Stress

(2012) H. Saito et al.   GENETICS

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction

(2011) Sebastian Alers et al.   Autophagy

CCCP induces autophagy in an AMPK-independent manner

(2011) Kyum-Yil Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

(2011) H. Cheong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-Aminoimidazole-4-carboxamide-1-β-ribofuranoside (AICAR) prevents nuclear translocation of constitutive androstane receptor by AMP-activated protein kinase (AMPK) independent manner

(2010) Yuichiro Kanno et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Hyperosmotic stress induces autophagy and apoptosis in recombinant Chinese hamster ovary cell culture

(2009) Young Kue Han et al.   BIOTECHNOLOGY AND BIOENGINEERING

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxonein vitro

(2009) Jan Lewerenz et al.   JOURNAL OF NEUROCHEMISTRY

A novel approach to enhancing cellular glutathione levels

(2008) Pamela Maher et al.   JOURNAL OF NEUROCHEMISTRY