Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy

Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate

(2018) Ovidiu C. Andronesi et al.   Nature Communications

Current therapeutic approaches to diffuse grade II and III gliomas

(2018) Alberto Picca et al.   Therapeutic Advances in Neurological Disorders

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

(2017) Oliver D. K. Maddocks et al.   NATURE

Highly specific determination of IDH status using edited in vivo magnetic resonance spectroscopy

(2017) Francesca Branzoli et al.   NEURO-ONCOLOGY

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Cystathionine: A novel oncometabolite in human breast cancer

(2016) Suvajit Sen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma

(2016) Changho Choi et al.   JOURNAL OF CLINICAL ONCOLOGY

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

(2016) Shira L Cramer et al.   NATURE MEDICINE

Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

(2016) Aurélie Kamoun et al.   Nature Communications

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

(2015) Isaac S. Harris et al.   CANCER CELL

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

(2015) Kensuke Tateishi et al.   CANCER CELL

Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198

(2015) R. J. Molenaar et al.   CANCER RESEARCH

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism

(2014) A. R. Grassian et al.   CANCER RESEARCH

Decreased Expression of Cystathionine β-Synthase Promotes Glioma Tumorigenesis

(2014) Naoharu Takano et al.   MOLECULAR CANCER RESEARCH

The epidemiology of glioma in adults: a "state of the science" review

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

3D GABA imaging with real-time motion correction, shim update and reacquisition of adiabatic spiral MRSI

(2014) Wolfgang Bogner et al.   NEUROIMAGE

An ANOCEF Genomic and Transcriptomic Microarray Study of the Response to Irinotecan and Bevacizumab in Recurrent Glioblastomas

(2014) Julien Laffaire et al.   Biomed Research International

Brain dynamic neurochemical changes in dystonic patients: A magnetic resonance spectroscopy study

(2012) Malgorzata Marjańska et al.   MOVEMENT DISORDERS

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

(2012) Changho Choi et al.   NATURE MEDICINE

Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy

(2012) O. C. Andronesi et al.   Science Translational Medicine

The transsulfuration pathway: a source of cysteine for glutathione in astrocytes

(2011) Gethin J. McBean   AMINO ACIDS

Isocitrate dehydrogenase mutations in gliomas

(2011) Changcun Guo et al.   CURRENT OPINION IN NEUROLOGY

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

(2011) Christian M. Metallo et al.   NATURE

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

(2011) Z. J. Reitman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma

(2010) Fonnet E. Bleeker et al.   ACTA NEUROPATHOLOGICA

Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1

(2010) M. J. Seltzer et al.   CANCER RESEARCH

Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas

(2009) Marc Sanson et al.   JOURNAL OF CLINICAL ONCOLOGY

Cystathionine γ-lyase: Clinical, metabolic, genetic, and structural studies

(2009) Jan P. Kraus et al.   MOLECULAR GENETICS AND METABOLISM

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated ELGN2-Mediated Oxygen-Sensing Response

(2008) Julie M. Koeman et al.   PLoS Genetics