Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes

The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes

(2018) Katherine Fletcher et al.   EMBO JOURNAL

A switch from canonical to noncanonical autophagy shapes B cell responses

(2017) Nuria Martinez-Martin et al.   SCIENCE

Membrane curvature in cell biology: An integration of molecular mechanisms

(2016) Iris K. Jarsch et al.   JOURNAL OF CELL BIOLOGY

TMEM166/EVA1A interacts with ATG16L1 and induces autophagosome formation and cell death

(2016) Jia Hu et al.   Cell Death & Disease

Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy

(2016) Ying Gao et al.   Cell Death & Disease

PI(5)P Regulates Autophagosome Biogenesis

(2015) Mariella Vicinanza et al.   MOLECULAR CELL

V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation

(2014) Oliver Florey et al.   Autophagy

Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners

(2014) Jun Hoe Kim et al.   Autophagy

Molecular Mechanism of Autophagic Membrane-Scaffold Assembly and Disassembly

(2014) Anna Kaufmann et al.   CELL

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

(2014) Hannah C. Dooley et al.   MOLECULAR CELL

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3

(2014) Sangeeta Nath et al.   NATURE CELL BIOLOGY

TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3

(2013) Emilio Boada-Romero et al.   EMBO JOURNAL

FIP200 regulates targeting of Atg16L1 to the isolation membrane

(2013) Taki Nishimura et al.   EMBO REPORTS

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

(2013) Naonobu Fujita et al.   JOURNAL OF CELL BIOLOGY

Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12

(2013) Z. Metlagel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex–dependent and –independent autophagy

(2012) Noor Gammoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

(2012) Chinatsu Otomo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Autophagy proteins in macroendocytic engulfment

(2012) Oliver Florey et al.   TRENDS IN CELL BIOLOGY

Kinetics Comparisons of Mammalian Atg4 Homologues Indicate Selective Preferences toward Diverse Atg8 Substrates

(2010) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like receptor signaling in the lysosomal pathways

(2008) Miguel A. Sanjuan et al.   IMMUNOLOGICAL REVIEWS

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL