MS progression is predominantly driven by age-related mechanisms – YES

The relationship of age with the clinical phenotype in multiple sclerosis

(2016) A Scalfari et al.   Multiple Sclerosis Journal

The relationship of age with the clinical phenotype in multiple sclerosis

(2016) A Scalfari et al.   Multiple Sclerosis Journal

Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated Syndrome

(2015) Orhun H. Kantarci et al.   ANNALS OF NEUROLOGY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Risk of relapse phenotype recurrence in multiple sclerosis

(2014) Tomas Kalincik et al.   Multiple Sclerosis Journal

Long-term outcome of paediatric-onset multiple sclerosis: a population-based study

(2012) Katharine E Harding et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis

(2012) M. Tutuncu et al.   Multiple Sclerosis Journal

Age and disability accumulation in multiple sclerosis

(2011) A. Scalfari et al.   NEUROLOGY