Proof of an Outer Membrane Target of the Efflux Inhibitor Phe-Arg-β-Naphthylamide from Random Mutagenesis

Contribution of AcrAB-TolC to multidrug resistance in an Escherichia coli sequence type 131 isolate

(2017) Sabine Schuster et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The Impact of Efflux Pump Inhibitors on the Activity of Selected Non-Antibiotic Medicinal Products against Gram-Negative Bacteria

(2017) Agnieszka Laudy et al.   MOLECULES

New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria

(2017) Gabriella Spengler et al.   MOLECULES

Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB

(2016) Sabine Schuster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump

(2016) Alfred D. Kinana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Fluorescent Microplate Assay Quantifies Bacterial Efflux and Demonstrates Two Distinct Compound Binding Sites in AcrB

(2015) Ramkumar Iyer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Importance of Real-Time Assays To Distinguish Multidrug Efflux Pump-Inhibiting and Outer Membrane-Destabilizing Activities in Escherichia coli

(2015) Rajeev Misra et al.   JOURNAL OF BACTERIOLOGY

Is Shiga Toxin-Negative Escherichia coli O157:H7 Enteropathogenic or Enterohemorrhagic Escherichia coli? Comprehensive Molecular Analysis Using Whole-Genome Sequencing

(2015) Mithila Ferdous et al.   JOURNAL OF CLINICAL MICROBIOLOGY

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Recent advances toward a molecular mechanism of efflux pump inhibition

(2015) Timothy J. Opperman et al.   Frontiers in Microbiology

Modification of the Susceptibility of Gram-Negative Rods Producing ESβLS to β-Lactams by the Efflux Phenomenon

(2015) Agnieszka E. Laudy et al.   PLoS One

Molecular Mechanism of MBX2319 Inhibition of Escherichia coli AcrB Multidrug Efflux Pump and Comparison with Other Inhibitors

(2014) Attilio V. Vargiu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Random Mutagenesis of the Multidrug Transporter AcrB from Escherichia coli for Identification of Putative Target Residues of Efflux Pump Inhibitors

(2014) Sabine Schuster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli

(2013) Timothy J. Opperman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Influence of Lipid A Acylation Pattern on Membrane Permeability and Innate Immune Stimulation

(2013) Yanyan Li et al.   Marine Drugs

The Efflux Inhibitor Phenylalanine-Arginine Beta-Naphthylamide (PAβN) Permeabilizes the Outer Membrane of Gram-Negative Bacteria

(2013) Ryan P. Lamers et al.   PLoS One

Role of the lpxM lipid A biosynthesis pathway gene in pathogenicity of avian pathogenic Escherichia coli strain E058 in a chicken infection model

(2013) Huiqing Xu et al.   VETERINARY MICROBIOLOGY

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

(2011) Ryosuke Nakashima et al.   NATURE

Evaluation of Multidrug Efflux Pump Inhibitors by a New Method Using Microfluidic Channels

(2011) Yoshimi Matsumoto et al.   PLoS One

Escherichia coliMutants That Synthesize Dephosphorylated Lipid A Molecules

(2010) Brian O. Ingram et al.   BIOCHEMISTRY

Use of resazurin to detect mefloquine as an efflux-pump inhibitor in Pseudomonas aeruginosa and Escherichia coli

(2009) Faustino Vidal-Aroca et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Efflux Pump, the Masked Side of ß-Lactam Resistance in Klebsiella pneumoniae Clinical Isolates

(2009) Jean-Marie Pages et al.   PLoS One

Site-Directed Mutagenesis Reveals Amino Acid Residues in the Escherichia coli RND Efflux Pump AcrB That Confer Macrolide Resistance

(2008) C. Wehmeier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Outer membrane permeability and antibiotic resistance

(2008) Anne H. Delcour   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Site-Directed Mutagenesis Reveals Putative Substrate Binding Residues in the Escherichia coli RND Efflux Pump AcrB

(2008) J. A. Bohnert et al.   JOURNAL OF BACTERIOLOGY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY