Microglial Depletion with Clodronate Liposomes Increases Proinflammatory Cytokine Levels, Induces Astrocyte Activation, and Damages Blood Vessel Integrity

Changes in motor function, cognition, and emotion-related behavior after right hemispheric intracerebral hemorrhage in various brain regions of mouse

(2018) Wei Zhu et al.   BRAIN BEHAVIOR AND IMMUNITY

Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes

(2018) Amber R. Hackett et al.   EXPERIMENTAL NEUROLOGY

20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

(2018) Xiaoning Han et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

(2018) Yubin Huang et al.   NATURE NEUROSCIENCE

Neuronal lysosomes

(2018) Shawn M. Ferguson   NEUROSCIENCE LETTERS

Inflammatory responses after intracerebral hemorrhage: From cellular function to therapeutic targets

(2018) Xi Lan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Clodronate as a Therapeutic Strategy against Osteoarthritis

(2017) Maria Valenti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotection of brain-permeable iron chelator VK-28 against intracerebral hemorrhage in mice

(2017) Qian Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglia ablation alleviates myelin-associated catatonic signs in mice

(2017) Hana Janova et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia Are Irrelevant for Neuronal Degeneration and Axon Regeneration after Acute Injury

(2017) Alexander M. Hilla et al.   JOURNAL OF NEUROSCIENCE

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhage

(2017) Che-Feng Chang et al.   NEUROBIOLOGY OF DISEASE

High plasticity of axonal pathology in Alzheimer’s disease mouse models

(2017) Lidia Blazquez-Llorca et al.   Acta Neuropathologica Communications

Anti-inflammatory Microglia/Macrophages As a Potential Therapeutic Target in Brain Metastasis

(2017) Kleopatra E. Andreou et al.   Frontiers in Oncology

Multimodality MRI assessment of grey and white matter injury and blood-brain barrier disruption after intracerebral haemorrhage in mice

(2017) Jie Yang et al.   Scientific Reports

Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways

(2016) Tian Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis

(2016) Jian Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke

(2016) D. Fernandez-Lopez et al.   JOURNAL OF NEUROSCIENCE

Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice

(2016) Elisa R. Zanier et al.   JOURNAL OF NEUROTRAUMA

Microglial Polarization and Inflammatory Mediators After Intracerebral Hemorrhage

(2016) Zhen Zhang et al.   MOLECULAR NEUROBIOLOGY

Origin, fate and dynamics of macrophages at central nervous system interfaces

(2016) Tobias Goldmann et al.   NATURE IMMUNOLOGY

Purinergic receptor P2RY12-dependent microglial closure of the injured blood–brain barrier

(2016) Nanhong Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wharton’s Jelly Transplantation Improves Neurologic Function in a Rat Model of Traumatic Brain Injury

(2015) Tian Cheng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury

(2015) Xiaoning Han et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The activation of NG2 expressing cells is downstream to microglial reaction and mediated by the transforming growth factor beta 1

(2015) Ping Xiang et al.   JOURNAL OF NEUROIMMUNOLOGY

NG2-proteoglycan-dependent contributions of oligodendrocyte progenitors and myeloid cells to myelin damage and repair

(2015) Karolina Kucharova et al.   Journal of Neuroinflammation

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

(2015) William D. Tap et al.   NEW ENGLAND JOURNAL OF MEDICINE

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterizing Newly Repopulated Microglia in the Adult Mouse: Impacts on Animal Behavior, Cell Morphology, and Neuroinflammation

(2015) Monica R. P. Elmore et al.   PLoS One

Distinct effect of zoledronate and clodronate on circulating levels of DKK1 and sclerostin in women with postmenopausal osteoporosis

(2014) Davide Gatti et al.   BONE

Activity-Driven Local ATP Synthesis Is Required for Synaptic Function

(2014) Vidhya Rangaraju et al.   CELL

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Mouse Models of Intracerebral Hemorrhage in Ventricle, Cortex, and Hippocampus by Injections of Autologous Blood or Collagenase

(2014) Wei Zhu et al.   PLoS One

Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-β1

(2013) Kana Sugimoto et al.   GLIA

NG2 Regulates Directional Migration of Oligodendrocyte Precursor Cells via Rho GTPases and Polarity Complex Proteins

(2013) F. Biname et al.   JOURNAL OF NEUROSCIENCE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Microglia Actively Regulate the Number of Functional Synapses

(2013) Kyungmin Ji et al.   PLoS One

An Innovative Cascade System for Simultaneous Separation of Multiple Cell Types

(2013) Arkadiusz Pierzchalski et al.   PLoS One

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures

(2012) Hiromi Kumamaru et al.   Journal of Neuroinflammation

Blood-Brain Barrier Permeability Is Increased After Acute Adult Stroke But Not Neonatal Stroke in the Rat

(2012) D. Fernandez-Lopez et al.   JOURNAL OF NEUROSCIENCE

The Balance between Receptor Recycling and Trafficking toward Lysosomes Determines Synaptic Strength during Long-Term Depression

(2012) M. Fernandez-Monreal et al.   JOURNAL OF NEUROSCIENCE

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke

(2011) J. V. Faustino et al.   JOURNAL OF NEUROSCIENCE

Selective targeting of perivascular macrophages for clearance of  -amyloid in cerebral amyloid angiopathy

(2009) C. A. Hawkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA