Article
Chemistry, Physical
Is Fatimah, Sesy Ardianti, Imam Sahroni, Gani Purwiandono, Suresh Sagadevan, Ruey-An Doong
Summary: The study conducted visible-light sensitization on PCH-ZnSi photocatalyst with Ru(Bpy)3+2, resulting in enhanced catalytic activity under UV and visible light exposure. The material showed increased specific surface area and improved pore distribution, leading to efficient degradation of methylene blue. Additionally, the stability of the material was demonstrated through XPS analysis, showing maintained efficiency over multiple cycles.
APPLIED CLAY SCIENCE
(2021)
Article
Chemistry, Applied
Xiaoyu Fan, Tingting Hong, Qilin Yang, Dilei Wang, Jing Peng, Wuqing Xiao, Xueying Yang, Xiaohong Hu, Chongli Yu, Shouying Du, Jie Bai
Summary: A method based on fingerprinting and chemometrics was developed to explore the influence of licorice origin on the quality of fried licorice. The results showed that the model was stable, reliable, and accurate in predicting licorice origin and provided a reference for origin traceability.
Article
Engineering, Environmental
Ying Jiang, Likun Xue, Hengqing Shen, Can Dong, Zhisheng Xiao, Wenxing Wang
Summary: This study investigates the dominant mechanisms and significant daytime sources of atmospheric nitrous acid (HONO) in various environments. The findings provide valuable insights into HONO formation processes and their relationships with different factors.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2022)
Article
Green & Sustainable Science & Technology
Athanasios Ragkos, Kentaro Hayashi, Joao Serra, Hideaki Shibata, Efstratios Michalis, Sadao Eguchi, Azusa Oita, Claudia Marques-dos-Santos Cordovil
Summary: Sustainable nitrogen management in agriculture requires coordinated efforts and holistic approaches. Stakeholders in Japan have differing views on nitrogen use and sustainability challenges. Further research is needed to address these issues and guide future policy design for more sustainable nitrogen use.
Article
Chemistry, Physical
Trupti Mohanty, Sharmistha Dutta Choudhury
Summary: This study presents a simple and unique supramolecular strategy for effective detection of fluoride and phosphate using reversible coordination of Al(III) with the chromophore quinizarin (QZ). The fluorescence ensembles formed by this strategy allow discrimination of biologically relevant phosphates, and the system operates in aqueous medium with ratiometric fluorescence mode.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Medicinal
Mario Lovric, Tomislav Duricic, Han T. N. Tran, Hussain Hussain, Emanuel Lacic, Morten A. Rasmussen, Roman Kern
Summary: Methods for dimensionality reduction contribute significantly to knowledge generation in high-dimensional modeling, reducing computing resources and improving training speed and flexibility. This study explores the utility of three unsupervised embedding techniques in toxicology classification tasks, finding UMAP as a potential pre-compression technique in the field.
Article
Chemistry, Applied
Shuang Guo, Xiaoyan Zhao, Yue Ma, Yubin Wang, Dan Wang
Summary: This study investigated the dynamic change in volatile components during the yellowing process of fresh-cut yams. Analysis of volatile components and enzyme activities revealed a certain pattern of changes. Principal component analysis showed that different yellowing processes of fresh-cut yams can be distinguished based on volatile compounds.
Article
Forestry
Ehsan Safari, Hossein Moradi, Andrea Seim, Rasoul Yousefpour, Mahsa Mirzakhani, Willy Tegel, Javad Soosani, Hans-Peter Kahle
Summary: The study reveals that the growth of the dominant oak species in the Central Zagros Mountains of western Iran is positively influenced by water availability and climatic conditions, with precipitation and temperature playing significant roles in the radial growth of the trees.
Article
Veterinary Sciences
J. Sanchez, M. Matas, F. J. Ibanez-Lopez, I. Hernandez, J. Sotillo, A. M. Gutierrez
Summary: This paper analyzes the association between stress and immune response in different diseases using salivary analytics. The study suggests that there are different intensities of associations between stress and immune markers, with oxidative stress markers showing high associations with adaptive immune markers. The paper also finds significant differences in salivary markers among different pathological conditions, indicating the potential for using salivary biomarkers to detect and characterize diseases in the future.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Engineering, Environmental
Jinming Xu, Huangmei Zhou, Yixue Zhang, Yu Zhao, Hao Yuan, Xiaoxiao He, Ying Wu, Sanjun Zhang
Summary: In recent years, the prevention and control of water pollution has received extensive attention. This study developed a fluorescent sensor array based on copper nanoclusters for the identification of metal ions and dissolved organic matter (DOM), with successful results in both classification and quantification.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Leila Narimani, Vannajan Sanghiran Lee, Yatimah Alias, Ninie Suhana Manan, Pei Meng Woi
Summary: Computational and experimental approaches were used to design a fluorescein derivative as a calcium ion (Ca2+) receptor. The study showed that the fluorescein derivative exhibited good selectivity and discrimination towards Ca2+ over potassium ion (K+) and magnesium ion (Mg2+). The results suggest that this method could be applied to the determination of cationic plant macronutrients in precision agriculture and other applications.
Article
Electrochemistry
Wei Huang, Bei Zhang, Yanling Rao
Summary: Establishing fingerprint profiles of chemical characteristics is an effective method internationally recognized for quality control of herbal medicines. This study examines geographical differences using Eucommia ulmoide bark and leaves. Electrochemical and Fourier transform infrared (FTIR) fingerprinting were used to obtain information on different samples. A common pattern for the profiles was established. The results showed that the differences in fingerprint profiles of samples from different origins could effectively identify their origins.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2023)
Article
Food Science & Technology
Md. Mizanur Rahman, Mario Shibata, Naho Nakazawa, Mst. Nazira Akhter Rithu, Emiko Okazaki, Shigeki Nakauchi
Summary: This study investigated the differences in freshness indicators between white and dark meat in frozen fish using fluorescence fingerprints. Results showed that dark meat had a higher accumulation rate of inosine and lower pH decrease rate compared to white meat during postmortem ice storage. Principal component analysis of fluorescence fingerprints spectra successfully distinguished white and dark meat in frozen fish. Additionally, partial least squares regression models revealed a more accurate prediction of freshness indicators in white meat compared to dark meat in the frozen state.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Soil Science
Xiangyu Liu, Mehran Rezaei Rashti, Lukas Van Zwieten, Maryam Esfandbod, Michael T. Rose, Chengrong Chen
Summary: Soil compaction combined with water deficit can lead to a significant decrease in microbial functions. This study investigated the microbial responses of two different sugarcane soils under the combined stresses of compaction and drought. The results showed that soil texture strongly influenced the microbial response to compaction, with clayey soil exhibiting higher microbial biomass carbon content and CO2 respiration compared to sandy soil. The findings highlight the importance of considering soil texture and moisture in assessing compaction impacts and developing management strategies.
SOIL & TILLAGE RESEARCH
(2023)
Article
Agriculture, Multidisciplinary
Jim Junhui Huang, Craig D'Souza, Magdalene Qiaohui Tan, Weibiao Zhou
Summary: The study reveals the significant impact of increasing white light intensity on the metabolic responses of choy sum, resulting in improved nutritional quality under high light intensity but increased pest-prevention compounds under low light intensity. Pearson's correlation analysis and principal component analysis further confirmed the relationship between light intensity and metabolites, providing crucial insights for improving vegetable nutritional values in indoor farming practices.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Analytical
Ruchita Shandilya, Roshani Kumari, Neha Bunkar, Arpit Bhargava, Koel Chaudhury, Irina Yu Goryacheva, Pradyumna Kumar Mishra
Summary: A novel nano-photonic dual hybrid assay system for rapid and specific detection of circulating cell free mitochondrial DNA (ccf-mtDNA) was assessed, showing high feasibility, selectivity, and versatility in estimating ccfmtDNA in different analytical platforms for disease risk assessment.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Physical
Xuanhao Chang, Egor O. Dobrolyubov, Sergey Krasnoshchekov
Summary: In this study, a fundamental quantitative study of the vibrational resonances of three (H2O)-O-16 H,D-isotopologues was carried out using a quartic Watson Hamiltonian. The resummation of the high-order divergent Rayleigh-Schrodinger perturbation theory series was used, and the resonance condition between a pair of states was formulated. The study revealed the existence of common complex energy solution branch points and the compatibility of different branches, as well as resonance effects matching specific polyad structures.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Review
Chemistry, Analytical
Olga A. Goryacheva, Tatiana D. Ponomaryova, Daniil D. Drozd, Alina A. Kokorina, Tatiana Yu Rusanova, Pradyumna K. Mishra, Irina Yu Goryacheva
Summary: Rapid assessment of biomarker levels in patients is an effective approach in the diagnosis and treatment of heart failure. BNP and NT-proBNP, as biomarkers of HF, have a high negative predictive value and are particularly useful in excluding HF as a cause of non-specific symptoms.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Ekaterina A. Mordovina, Valentina O. Plastun, Arkady S. Abdurashitov, Pavel I. Proshin, Svetlana V. Raikova, Daniil N. Bratashov, Olga A. Inozemtseva, Irina Yu. Goryacheva, Gleb B. Sukhorukov, Olga A. Sindeeva
Summary: This study demonstrates the fabrication of smart films with microchamber arrays made of polylactic acid (PLA) that can effectively release antibiotics and prolong release duration. The concentration and thickness of the films affect the release amount and time of the antibiotic. Additionally, the therapeutic ultrasound can trigger accelerated antibiotic release, which inhibits bacterial growth.
Article
Chemistry, Analytical
Anna V. Shik, Irina A. Stepanova, Irina A. Doroshenko, Tatyana A. Podrugina, Mikhail K. Beklemishev
Summary: Array-based optical sensing is an efficient technique for determining and differentiating small organic molecules. This study presents a simple and rapid strategy using carbocyanine dyes to obtain an optical response from a wide range of low-molecular-weight organic compounds, employing both aggregation and oxidation mechanisms. The feasibility of discriminating nine medicinal compounds was demonstrated using principal component analysis, making this platform a simple and rapid method for recognizing analytes of various nature.
Article
Chemistry, Multidisciplinary
Alexander Yu Tolbin, Boris N. Tarasevich, Mikhail K. Beklemishev, Valery K. Brel, Victor E. Pushkarev
Summary: This study investigated the reaction product of 2-hydroxy-9(10),16(17),23(24)-tri-tert-butyl-29H,31H- phthalocyanine with hexachlorocyclotriphosphazene. Experimental and computational results showed that the reaction product was an inseparable mixture of three diastereomers.
Review
Chemistry, Analytical
Yuliya A. Podkolodnaya, Alina A. Kokorina, Tatiana S. Ponomaryova, Olga A. Goryacheva, Daniil D. Drozd, Mikhail S. Khitrov, Lingting Huang, Zhichao Yu, Dianping Tang, Irina Yu. Goryacheva
Summary: Luminescent carbon nanostructures (CNSs) have attracted attention due to their photoluminescent properties, structural features, low toxicity, and various applications. The application of a silica matrix reduces the challenges in separating CNSs and improves their optical properties. In addition, multifunctional particles combining CNSs with other nanoparticles show promise in diverse fields.
Review
Chemistry, Multidisciplinary
Pooja Ratre, Bulbul Jain, Roshani Kumari, Suresh Thareja, Rajnarayan Tiwari, Rupesh Kumar Srivastava, Irina Yu Goryacheva, Pradyumna Kumar Mishra
Summary: Graphene quantum dots (GQDs) are natural crystalline semiconductors that have unique physical and chemical properties. Compared to inorganic quantum dots, GQDs have advantages such as biocompatibility and low toxicity, making them promising materials for nanophotonic applications. Their photonic compliant properties make GQDs useful as novel probes for biomolecule detection and molecular interaction studies. GQDs-based strategies in liquid biopsy could be a step towards early diagnosis, prognosis, treatment monitoring, and outcome prediction of non-communicable diseases.
Review
Chemistry, Analytical
Alexandra I. Arzhanukhina, Nadezhda S. Komova, Anton M. Pavlov, Alexey A. Serdobintsev, Tatiana Yu. Rusanova, Irina Yu. Goryacheva
Summary: Surface-enhanced Raman spectroscopy (SERS) is a powerful and up-to-date method in analytical chemistry, known for its high sensitivity and fingerprint recognition capabilities. In the medical field, SERS has been actively developed for label-free analysis of biologically important substances and potential on-site detection of toxins and food safety. Plasmonic nanostructures are essential for obtaining SERS signals, and electrospun nanofibers are a promising substrate due to their various advantages. This review summarizes the methods of incorporating plasmonic nanostructures into electrospun nanofiber substrates and provides detailed insights into the analytical applications of SERS-active electrospun nanofibers with embedded nanostructures for biologically significant molecules. Furthermore, the future prospects of these substrates in bioanalysis are discussed as the most promising area in analytical chemistry.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
P. A. Demina, O. A. Sindeeva, A. M. Abramova, M. S. Saveleva, G. B. Sukhorukov, I. Y. Goryacheva
Summary: This article investigates the performance of fluorescent photoconvertible polymer markers under different laser conditions and successfully achieves cell labeling. The authors describe the performance characteristics of fluorescent polymer capsules as an aqueous suspension and as a single capsule, and demonstrate the potential of these fluorescent markers for long-term live cell labeling.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Chemistry, Analytical
Anna V. Shik, Irina A. Stepanova, Irina A. Doroshenko, Tatyana A. Podrugina, Mikhail K. Beklemishev
Summary: Optical sensor arrays are commonly used to obtain fingerprints and solve recognition and identification problems. This study proposes a method for discriminating proteins based on their oxidation reactions. By adding carbocyanine dyes and analyzing the spectral characteristics, the method successfully recognizes model proteins and rennet samples with rapidity and simplicity using commercially available reagents.
Article
Chemistry, Analytical
Svetlana A. Mescheryakova, Ivan S. Matlakhov, Pavel D. Strokin, Daniil D. Drozd, Irina Yu. Goryacheva, Olga A. Goryacheva
Summary: Doxorubicin (DOX) is a commonly used anti-tumor drug in chemotherapy, but it has high cardio-, neuro- and cytotoxicity. Therefore, continuous monitoring of DOX concentrations in biofluids and tissues is important. This study demonstrates the capabilities of analytical nanosensors based on the quenching of fluorescence of alloyed CdZnSeS/ZnS quantum dots (QDs) for operative DOX detection. Optimized turn-off fluorescence nanosensors were developed for direct DOX determination in undiluted human plasma.
Article
Chemistry, Physical
Natalia E. Markina, Irina Yu. Goryacheva, Alexey V. Markin
Summary: The paper discusses the use of CD-modified AgNPs for the improvement of MTX determination through SERS. The CD-modified AgNPs increased the SERS signal of MTX in neutral media, simplifying the analysis and reducing the influence of endogenous components. The assay showed satisfactory precision, accuracy, and limit of detection for MTX determination in real human urine samples.
COLLOIDS AND INTERFACES
(2023)
Article
Chemistry, Applied
Anna Shik, Evgenii Skorobogatov, Ulyana A. Bliznyuk, Alexander P. Chernyaev, Valentina M. Avdyukhina, Polina Yu. Borschegovskaya, Sergey A. Zolotov, Maksim O. Baytler, Irina A. Doroshenko, Tatyana A. Podrugina, Mikhail K. Beklemishev
Summary: High-energy electron beam and X-ray processing can extend the storage life of foods and help combat pests and pathogens. This study developed simple methods, based on indicator reactions, to detect irradiation in potato tubers and estimate the absorbed dose.
Article
Chemistry, Analytical
Arseniy A. Pypin, Anna V. Shik, Irina A. Stepanova, Irina A. Doroshenko, Tatyana A. Podrugina, Mikhail K. Beklemishev
Summary: Optical fingerprints are commonly used for chemometrics-assisted recognition of different types of samples. This study developed a reaction in an organic solvent to recognize fat-soluble samples and evaluated its discrimination accuracy. The results indicate the promising viability of kinetics-based discrimination strategy.
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)