Article
Chemistry, Applied
Yi-Chuan Huang, Xi Chu, Wen-Hao Li, Shi-Sheng Zhao, Jia-Xin Zhang, Zhen-Qiang Qin, Hong-Yan Li, Wei Xue
Summary: In order to detect harmful excessive thiourea (TU) in the environment and the human body, four iridium(III) complexes were designed and synthesized as efficient chemosensors. These complexes exhibited emission peaks between 541 nm and 583 nm, with PLQY ranging from 0.12 to 0.26 and lifetime in the range of 2.65-2.74 μs. All four complexes showed significant turn-on response to TU with a low limit of detection of 10-8 M. Furthermore, these iridium(III) complex-based chemosensors exhibited excellent recoveries towards TU in various juice samples.
Article
Chemistry, Multidisciplinary
Fenqiang Luo, Meng Guo, Liyan Zheng, Zhixiong Cai
Summary: An efficient fluorescence-enhanced probe, named CIT-Z, was developed for the detection of cyanide ions (CN-) based on a tetraphenylethene coordinated copper-iodide complex. The prepared coordination polymers exhibited a 3-fold-interpenetrating network structure with excellent optical properties and chemical stability. The probe showed high selectivity and sensitivity towards CN- with a detection limit of 0.1 μM in real water samples.
Article
Chemistry, Analytical
Wanhe Wang, Jianhua Liu, Lingtan Kong, Ling Wang, Dou Niu, Jing Wang, Chung-Hang Leung
Summary: A new method is presented for the one-step synthesis and real-time monitoring of iridium(III) complex-functionalized AuNPs. The functionalized AuNPs were obtained by the reduction of Au3+ ions by the alkyne group of iridium(III) complexes, with the anchoring iridium(III) complexes on the surface of the nanoparticles. Luminescence monitoring of the formation process of the functionalized AuNPs was achieved by quenching the luminescence of the iridium(III) complexes with AuNPs.
Review
Biochemistry & Molecular Biology
Ambreen Rashid, Sahidul Mondal, Pradyut Ghosh
Summary: Improvements in designing receptors for anion detection and quantification have made remarkable progress in anion chemistry. The development of luminescent chemosensors, particularly those based on ruthenium and iridium complexes, has advanced due to their modular synthesis and desirable properties. This review summarizes the recent advancements in ruthenium(II) and iridium(III)-based complexes as luminescent chemosensors for anion sensing, with a focus on designing aspects for producing quantifiable outputs when interacting with different inorganic anions.
Review
Chemistry, Analytical
Ankita Roy, Mahasweta Nandi, Partha Roy
Summary: The development of dual chemosensors is gaining special attention due to its advantages over single analyte chemosensors. By compiling published pure organic compounds as dual chemosensors, a library can be built to provide ready information in this field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Organic
Pooja, Harsh Pandey, Sarika Aggarwal, Monika Vats, Varun Rawat, Seema R. Pathak
Summary: Due to their intense and persistent fluorescence emission, structural flexibility, and excellent biocompatibility, coumarins are widely used in developing new fluorescent chemosensors. They have been used for sensing various metal ions and have shown potential applications in imaging, biology, and medical research.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Anastasia Yu. Gitlina, Viktoria Khistiaeva, Alexey Melnikov, Mariia Ivonina, Vladimir Sizov, Dar'ya Spiridonova, Anna Makarova, Denis Vyalikh, Elena Grachova
Summary: Two methods of post-synthetic modification (Suzuki coupling and CuAAC click-reaction) were applied to Ir(iii) complexes to introduce a highly selective donor site. The potential of post-synthetic modification for controlled construction of d-d and d-f binuclear complexes was demonstrated using functionalized complexes. Characterization techniques such as elemental analysis, NMR spectroscopy, mass spectrometry, FTIR spectroscopy, and X-ray diffraction analysis were used to analyze the obtained complexes. The coordination of the diimine donor site to the Ln(iii) center was confirmed through XPS and NEXAFS spectroscopy. The photophysical properties and luminescent characteristics of the complexes were investigated, and TDDFT calculations were used to explain the luminescence mechanism.
DALTON TRANSACTIONS
(2023)
Review
Chemistry, Physical
Ram Kumar, Bholey Singh, Parveen Gahlyan, Rakesh Kumar, Balaram Pani
Summary: Colorimetric chemosensors are devices that convert chemical information into visible and organized signals for analysis and scientific transmission. The design and synthesis of colorimetric and fluorometric chemosensors for D-metal ion recognition have significant importance in catalysis, medical diagnostics, analytical and physiological, and environmental chemistry. They offer accurate and low-cost detection of D-metal ions with rapid response, high sensitivity, and selectivity. This review provides in-depth knowledge of colorimetric and fluorometric chemosensors for D-metal ion detection in the literature from 2020 to 2022.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Organic
Wen-Ying He, Ning Liu, Xu Jiang, Yan-Zhen Zheng, Zhi-Wei Lin, Jiang-Shan Shen
Summary: Introducing a weak covalent bond to transform a highly fluorescent molecule into a non-fluorescent probe provides a new approach for detecting nucleophilic targets with enhanced sensitivity. This study reports the first tetraphenylethene-based probe (TPEONO2) that utilizes the cleavage reaction of a sulfonyl ester bond to induce aggregation-induced emission (AIE) for the sensing of F- ions in aqueous solution.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Wen-Jin Wang, Yu-Yi Ling, Yan-Mei Zhong, Zhi-Yuan Li, Cai-Ping Tan, Zong-Wan Mao
Summary: This study reports on an Ir-III complex that can induce ferroptosis, a programmed cell death pathway, under acidic conditions. The complex affects pathways related to cancer immunity and has the potential for effective cancer immunotherapy.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Yong-Qiang Xie, You-Ming Zhang, Zhao-Hui Li, Xiao-Ni Qi, Hong Yao, Bing-Bing Shi, Wen-Juan Qu, Tai-Bao Wei, Qi Lin
Summary: The dual-channel chemical probe DH has high selectivity and sensitivity for Cu2+ and CN-, achieving reversible highly sensitive response. By sequentially adding Cu2+ and EDTA, DH can be used as a hypersensitive logic gate for Cu2+ detection and shows specific response to CN-. With great potential in practical applications, DH offers a promising approach for ion test strips and HeLa cell imaging reagents.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Analytical
Hyun Seung No, Taemin Kim, Jong-In Hong
Summary: Glutathione is an abundant biological thiol involved in antioxidant defense systems in human cells, and its lack can increase the risk of oxidative stress, leading to cancer progression. Dual sensors based on iridium complexes were developed for the selective detection of GSH, with high selectivity and successful application for determining GSH concentrations in human serum using ECL methods.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Applied
Chan Hee Ryu, Junseop Lim, Mingi Kim, Ilsup Shin, Jun Yeob Lee, Kang Mun Lee
Summary: Researchers have developed a blue-emitting iridium complex, IrTrz, based on a 1,2,4-triazole ligand, which exhibits stable blue emission, high thermal stability, and excellent electrochemical stability. Multilayer phosphorescent OLEDs using IrTrz as the blue emitter show low turn-on voltages and high external quantum efficiencies, with stable operational lifetimes exceeding 690 h.
Article
Biochemistry & Molecular Biology
Ben Liu, Jing Long, Meng Zhang, Kaiming Cheng, Xin Gao, Yibo Zhou, Yi Li, Zilong Tang, Wei Zhang
Summary: This study successfully achieved the goal of detecting H2S in mitochondria through exploring an iridium complex, which displays high selectivity and sensitivity, low cell toxicity, and has been successfully used for in vitro and in vivo H2S imaging.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Chemistry, Analytical
Huachao Che, Nengneng Li, Yulun Nie, Xike Tian, Yong Li, Liqiang Lu, Yongqiang Wang
Summary: A convenient method for simultaneous detection of As(III/V), Cr(III/VI), and Fe(II/III) has been developed using a sensor array. The array showed low detection limit and could achieve simultaneous qualitative and quantitative results for composite samples of multiple metal ions.
Article
Biochemical Research Methods
K. Ramki, G. Thiruppathi, Selva Kumar Ramasamy, P. Sundararaj, P. Sakthivel
Summary: A chromone-based ratiometric fluorescent probe L2 was developed for the selective detection of Hg(II) in a semiaqueous solution. The probe exhibited enhanced fluorescence in its aggregated state and even higher fluorescence when chelated with Hg(II). The probe demonstrated high sensitivity and specificity for Hg(II) detection and was successfully applied for imaging Hg(II) in a living model.
Article
Biochemical Research Methods
Qun Zhang, Rui Yang, Gang Liu, Shiyan Jiang, Jiarui Wang, Juqiang Lin, Tingyin Wang, Jing Wang, Zufang Huang
Summary: This research aims to develop a cost-effective and portable method for measuring creatinine levels using the enhanced Tyndall effect phenomenon. The method offers a promising solution for monitoring renal healthcare in resource-limited settings.
