Article
Oncology
Nazi Nejat, Amir Rahbarian, Fatemeh Mehrabi, Fatemeh Rafiei
Summary: This study investigated the prevalence of complementary and alternative medicine (CAM) use among cancer patients in Iran. The findings showed that 44.3% of the 320 participants were using CAM. Most patients used CAM to improve their physical condition and used it alongside conventional medical treatments. Common CAM treatments included visiting holy places, practicing yoga, engaging in prayer therapy, and using medicinal plants and special diets.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Clinical Neurology
Benedicte Marie Finger, Annika Triller, Ashley M. Bourke, Gert Jan Lammers, Christian Veauthier, Merve Yildizli, Ulf Kallweit
Summary: This study investigated the frequency and characteristics of complementary and alternative medicine (CAM) use in German narcolepsy patients. 15% of patients were using CAM at the time of the survey, and an additional 18% reported past use. The most commonly used CAM treatments were vitamins/trace elements, homeopathy, and meditation. CAM users were more likely to experience side effects from medication and have low adherence to pharmacological treatment.
Article
Oncology
Panagiotis A. Konstantinopoulos, Jung-Min Lee, Bo Gao, Rowan Miller, Jung-Yun Lee, Nicoletta Colombo, Ignace Vergote, Kelly M. Credille, Suzanne R. Young, Samuel McNeely, Xuejing Aimee Wang, Aimee Bence Lin, Ronnie Shapira-Frommer
Summary: This study aimed to evaluate the efficacy and safety of using prexasertib, a CHK1 inhibitor, in treating high-grade serous ovarian cancer. The results showed that prexasertib demonstrated durable single agent activity to a certain extent and its effects were not influenced by clinical characteristics, BRCA status, or prior therapies, including PARPi. The study also emphasized the need for alternative biomarker approaches to identify responders.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Chemistry, Medicinal
Qingli Cui, Yanhui Hu, Dongyang Ma, Huaimin Liu
Summary: Anlotinib showed moderate improvements in progression-free survival and overall survival in patients with platinum-resistant or platinum-refractory ovarian cancer, indicating it may be a new treatment option for this group of patients.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Oncology
J. Huebner, R. Muecke, O. Micke, F. -J Prott, L. Josfeld, J. Buentzel, J. Buentzel
Summary: This study investigates whether cancer patients' concepts of how and why cancer develops have an influence on their choice of complementary and alternative medicine (CAM). The results show that many patients use CAM, with supplements, relaxation techniques, and homeopathy being the most commonly used methods. While all lay etiological beliefs are associated with the overall usage of CAM, there is no association between specific etiological concepts and types of CAM used. These findings suggest that patients may have other needs addressed by CAM.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Oncology
Madhavi Manyam, Amanda J. Stephens, Jessica A. Kennard, Jane LeBlanc, Sarfraz Ahmad, James E. Kendrick, Robert W. Holloway
Summary: The study demonstrated promising safety, clinical activities, and immune activation of intraperitoneal Olvi-Vec virotherapy in patients with platinum-resistant or refractory ovarian cancer (PRROC), indicating the need for further clinical investigation.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Sebastiano Mercadante, Giuseppe Bellavia, Alessio Lo Cascio, Marcella Dabbene, Grazia di Silvestre, Alessandra Casuccio
Summary: The study surveyed 283 advanced cancer patients receiving home care and found that only 4.2% of patients were using complementary alternative medicines (CAM). The indications and types of CAM varied among patients, with different costs involved. Further analysis was not performed due to the limited number of patients using CAM.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Integrative & Complementary Medicine
Abdul Rahman Jazieh, Khadega A. Abuelgasim, Husam Ardah, Mohammad Alkaiyat, Omar B. Da'ar
Summary: This study evaluated the trends of complementary and alternative medicine (CAM) use among cancer patients, showing significant changes in CAM use over the decade, reflecting major societal and cultural changes in the beliefs towards cancer treatment.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2021)
Article
Oncology
Vicente Escudero-Vilaplana, Roberto Collado-Borrell, Patricia Gomez Martinez-Sagrera, Cristina Villanueva-Bueno, Jose Luis Revuelta-Herrero, Eva Gonzalez-Haba, Angela Hoyo-Munoz, Yolanda Jerez Gilarranz, Belen Marzal-Alfaro, Ana Herranz, Miguel Martin, Maria Sanjurjo
Summary: This study examined the use of complementary and alternative medicine (CAM) in cancer patients and the interactions between CAM and antineoplastic agents. The results showed a high incidence of interactions between CAM and antineoplastic agents, with herbal products being the most commonly used CAM. Family and friends were the primary sources of information that led patients to start taking CAM, and more than half of the patients did not inform their doctors about their CAM use.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Review
Pharmacology & Pharmacy
Hongmin Chu, Seunghwan Moon, Jeongsu Park, Seongjun Bak, Youme Ko, Bo-Young Youn
Summary: The development of artificial intelligence in complementary and alternative medicine has been rapidly advancing. This systematic scoping review identified three main categories of AI usage in CAM, including acupuncture treatment, tongue and lip diagnoses, and herbal medicine. Future research should focus on verifying and validating these AI models through large-scale clinical trials.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Clinical Neurology
Panagiotis Kerezoudis, Evangelia N. Kerezoudi, Abdurehman Choudhry, Benjamin T. Himes, Ian F. Parney
Summary: Many patients and caregivers of glioma seek CAM methods to comfort themselves and cope with cancer medication side effects. This study summarizes the existing evidence on the safety and efficacy of CAM treatments for gliomas.
Article
Oncology
Shahla Bari, Iloabueke Chineke, Alicia Darwin, Anam Umar, Heather Jim, Jameel Muzaffar, Omer Kucuk
Summary: This study revealed that CAM awareness and usage rates are relatively low among medically underserved cancer patients, but there is a strong interest in gaining more information about various CAM options and potential benefits. Female patients and those with higher education levels tend to be more inclined towards the use of CAM therapies, with meditation, herbal remedies, and yoga being the most commonly chosen modalities.
INTEGRATIVE CANCER THERAPIES
(2021)
Article
Oncology
Clemens P. J. G. Wolf, Tobias Rachow, Thomas Ernst, Andreas Hochhaus, Bijan Zomorodbakhsch, Susan Foller, Matthias Rengsberger, Michael Hartmann, Jutta Huebner
Summary: The study aimed to analyze the use of complementary and alternative medicine (CAM) supplements in cancer patients and identified younger age and a longer cancer history as predictors for CAM supplement use. It was found that over-the-counter CAM supplements can potentially interact with conventional cancer therapy, emphasizing the importance of physician-patient communication and monitoring for interactions to ensure patient safety.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ashwaq H. S. Yehya, Muhammad Asif, Amin M. S. Abdul Majid, Chern E. Oon
Summary: This study demonstrates that ethanolic extract of Orthosiphon stamineus sensitizes pancreatic cancer cells to gemcitabine by reducing multidrug-resistant proteins and molecules related to epithelial-mesenchymal transition. On the other hand, the combination of rosmarinic acid and gemcitabine did not show additional effects on cellular senescence or apoptosis.
BIOMEDICAL JOURNAL
(2021)
Review
Pharmacology & Pharmacy
Elvin Peter Chizenga, Heidi Abrahamse
Summary: Good medicine is based on good science, open to new paradigms, and requires a well-structured and multifactorial treatment regime for complex diseases like cancer. Integrative oncology combines CAM therapies with modern medicine, emphasizing the importance of understanding genetic and epigenetic characteristics of individual cancers. Targeting the specific features of tumors at the genetic and epigenetic levels is crucial for successful therapy.
Article
Obstetrics & Gynecology
Woo Yeon Hwang, Minjung Lee, Dong Hoon Suh, Kidong Kim, Jae Hong No, Yong Beom Kim, Ju-Hyun Kim
Summary: In patients with epithelial ovarian cancer, prior use of carboplatin was identified as an independent risk factor for carboplatin-related hypersensitive reactions, while hypersensitivity to carboplatin did not impact overall survival.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Oncology
Woo Yeon Hwang, Suk-Joon Chang, Hee Seung Kim, Nam Kyeong Kim, Tae Hun Kim, Yeorae Kim, Tae Wook Kong, Eun Ji Lee, Soo Jin Park, Seung Hyuk Shim, Joo-Hyuk Son, Dong Hoon Suh, Eun Jung Yang
Summary: This study aims to evaluate the incidence and risk factors for gastrointestinal and genitourinary fistula or perforation in recurrent cervical cancer patients who received pelvic radiation therapy. The study found that the inclusion of bevacizumab in chemotherapy regimens increases the risk of fistula/perforation formation. No other independent risk factors were identified.
Article
Obstetrics & Gynecology
Woo Yeon Hwang, Yong Beom Kim, Sa Ra Lee, Dong Hoon Suh, Kidong Kim, Jae Hong No
Summary: This study aimed to evaluate the efficacy and safety of low-level light therapy (LLLT) device for the treatment of overactive bladder (OAB). The results showed that compared to the sham group, the LLLT group had significantly reduced episodes of urge urinary incontinence (UUI) and urinary incontinence after 12 weeks of treatment, and LLLT also tended to improve the OAB symptoms and quality of life. This study suggests that LLLT may be a safe and effective treatment for OAB.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2022)
Article
Obstetrics & Gynecology
Woo Yeon Hwang, Kidong Kim, Hye Yon Cho, Eun Joo Yang, Dong Hoon Suh, Jae Hong No, Jung Ryeol Lee, Jung Won Hwang, Sang-Hwan Do, Yong Beom Kim
Summary: This study aimed to identify an appropriate scoring system for predicting postoperative urinary retention (POUR) after gynaecological laparoscopic surgery for benign disease. The results showed that the voiding VAS score is a simple and useful method for identifying patients at risk of POUR.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Do Jin Nam, Chang-Mo Oh, Eunhee Ha, Min-Ho Kim, Eun Hye Yang, Hyo Choon Lee, Soon Su Shin, Woo Yeon Hwang, Ann Hee You, Jae-Hong Ryoo
Summary: This study examined the dose-response relationship between smoking amounts (pack-years) and the risk of developing pancreatic cancer in Korean men. The results showed that the risk of developing pancreatic cancer was higher in current smokers compared to former smokers, indicating that smoking cessation may have a protective effect.
EPIDEMIOLOGY AND HEALTH
(2022)
Article
Gastroenterology & Hepatology
Sung Keun Park, Min-Ho Kim, Ju Young Jung, Chang-Mo Oh, Eunhee Ha, Eun Hye Yang, Hyo Choon Lee, Woo Yeon Hwang, Ann Hee You, Jae-Hong Ryoo
Summary: This study analyzed the risk of gastroduodenal ulcer according to changes in smoking status for more than 5 years. The results showed that current smokers had a significantly higher risk for gastroduodenal ulcer compared to past smokers, and heavy smokers had the highest risk.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Endocrinology & Metabolism
Sung Keun Park, Ju Young Jung, Min -Ho Kim, Chang-Mo Oh, Eunhee Ha, Soon Su Shin, Hyo Choon Lee, Woo Yeon Hwang, Jae-Hong Ryoo
Summary: This study examined the association between changes in proteinuria and the risk of cerebral infarction. The results showed that all types of proteinuria changes were associated with an increased risk of cerebral infarction.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
Article
Oncology
Joo-Hyuk Son, Tae-Wook Kong, Soo Jin Park, Eun Ji Lee, Hee Seung Kim, Nam Kyeong Kim, Yeorae Kim, Woo Yeon Hwang, Dong Hoon Suh, Tae Hun Kim, Eun Jung Yang, Seung-Hyuk Shim, Suk-Joon Chang
Summary: The benefits of secondary cytoreductive surgery (SCS) in recurrent ovarian cancer patients are limited to cases of complete resection. We propose limited regional platinum-sensitive recurrence (≤3 regions or limited carcinomatosis) without ascites as the optimum selection criteria for SCS.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Endocrinology & Metabolism
Sung Keun Park, Min-Ho Kim, Ju Young Jung, Chang-Mo Oh, Eunhee Ha, Do Jin Nam, Eun Hye Yang, Woo Yeon Hwang, Sangho Lee, Jae-Hong Ryoo
Summary: Long-term and heavy smoking increases the risk of microvascular complications, including nephropathy and neuropathy, in patients with diabetes mellitus. Quitting smoking and reducing smoking amount are crucial in preventing microvascular complications in diabetic patients.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Article
Public, Environmental & Occupational Health
Sung Keun Park, Ju Young Jung, Min -Ho Kim, Chang-Mo Oh, Eunhee Ha, Eun Hye Yang, Hyo Choon Lee, Soonsu Shin, Woo Yeon Hwang, Sangho Lee, So Youn Shin, Jae-Hong Ryoo
Summary: This study found that experiencing proteinuria increased the risks of ischemic heart disease (IHD), acute myocardial infarction (AMI), and angina pectoris, even after proteinuria resolved. Persistent proteinuria had the highest risk, followed by incident and resolved proteinuria.
EPIDEMIOLOGY AND HEALTH
(2023)
Article
Oncology
Woo Yeon Hwang
Summary: This is a case report about a 38-year-old woman who presented with elevated CA 19-9 levels and was diagnosed with endometriosis that evolved into endometrioid carcinoma. The case highlights that sudden elevation of CA 19-9 level might be a sign of malignancy, small asymptomatic endometriosis should not be ignored, and incidental diagnosis of ovarian cancer should be carefully assessed by surgical staging.
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
(2023)
Meeting Abstract
Oncology
Joo-Hyuk Son, Tae-Wook Kong, Soo Jin Park, Eun Ji Lee, Hee Seung Kim, Nam Kyeong Kim, Yeorae Kim, Woo Yeon Hwang, Dong Hoon Suh, Tae Hun Kim, Eun Jung Yang, Seung Hyuk Shim, Suk-Joon Chang
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Oncology
Woo Yeon Hwang, Dong Hoon Suh, Kidong Kim, Yong Beom Kim, Jae Hong No
Summary: This study evaluated the prognostic value of HE4 as a tumor marker in cervical cancer. The results showed that high levels of HE4 expression were associated with poor overall survival, indicating a poor prognosis for cervical cancer patients.
Meeting Abstract
Oncology
Joo-Hyuk Son, Tae-Wook Kong, Soo Jin Park, Eun Ji Lee, Hee Seung Kim, Nam Kyeong Kim, Yeorae Kim, Woo Yeon Hwang, Dong Hoon Suh, Tae Hun Kim, Eun Jung Yang, Seung-Hyuk Shim, Suk-Joon Chang
GYNECOLOGIC ONCOLOGY
(2022)
Meeting Abstract
Oncology
Joo-Hyuk Son, Tae-Wook Kong, Soo Jin Park, Eun Ji Lee, Hee Seung Kim, Nam Kyeong Kim, Yeorae Kim, Woo Yeon Hwang, Dong Hoon Suh, Tae Hun Kim, Eun Jung Yang, Seung-Hyuk Shim, Suk-Joon Chang
GYNECOLOGIC ONCOLOGY
(2022)