Article
Chemistry, Analytical
Mingyi Yao, Jian Liu, Narengaowa, Yonggu Li, Feng Zhao
Summary: Accurate detection of natural dyes in archaeological textiles is achieved using in situ detection of fibers by surface-enhanced Raman scattering (SERS). Two methods for the preparation of SERS substrates are presented, offering advantages such as rapid preparation, easy handling, low cost, high sensitivity, and excellent reproducibility. This minimally invasive, in situ analytical approach provides a valuable tool for analytical applications where sampling is limited.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Quan Hong, Lan Jiang, Sumei Wang, Ji Huang, Jiaxin Sun, Xin Li, Pei Zuo, Jiangang Yin, Jiangang Lu
Summary: In recent years, metallic nanoparticle-two-dimensional material hybrids have been extensively used in photocatalysis and photoreduction. This study introduces a femtosecond laser reduction approach for the fast fabrication of metallic nanoparticle-two-dimensional material hybrids using temporally shaped pulses. The proposed one-step in situ fabrication method eliminates the additive separation process and shows morphological controllability.
Article
Environmental Sciences
Shanshan Dong, Helin Hua, Xin Wu, Xuhui Mao, Na Li, Xinping Zhang, Kun Wang, Shengyun Yang
Summary: In this study, a silver nanoparticle-loaded PVDF ultrafiltration membrane was prepared by an in-situ photoreduction method to mitigate membrane biofouling. The antibacterial experiments showed favorable antibacterial performance and stability of the membrane.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Tzyy-Jiann Wang, Ji-Sheng Chen, An-Ting Lee, Zhe-Yuan Liu
Summary: In this study, anisotropic growth of silver nanostructures was induced on ferroelectric templates through a surfactant-assisted photoreduction process, resulting in the formation of silver nanoplates. The effects of surfactant adsorption on nanoparticle morphology and properties were investigated, showing that their influence levels depend on the ratio of surfactant concentration to precursor concentration. The produced silver nanostructures exhibited superior SERS features.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Huijuan Zhang, Dong Wang, Duan Zhang, Tongtong Zhang, Longkun Yang, Zhipeng Li
Summary: A surface-enhanced Raman scattering (SERS) substrate functionalized with I- was developed for rapid and sensitive Hg2+ sensing on a microfluidic platform. The sensor demonstrated fast response, high sensitivity, and good selectivity towards Hg2+, with detectable concentrations as low as 1 fM. Real water sample detection showed promising results for on-site Hg2+ detection.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Bismark Nogueira da Silva, Moyra Freitas Vieira, Celly Mieko Shinohara Izumi
Summary: The morphological control of plasmonic silver nanoparticles is a challenge in the field, and in this study, the use of polyaniline (PANI) nanofibers with different surface properties and dopants was explored to synthesize AgNPs with different shapes. The resulting nanocomposites showed distinct surface-enhanced Raman spectroscopy (SERS) enhancements.
Article
Chemistry, Physical
Anna A. Ermina, Nikolay S. Solodovchenko, Kristina Prigoda, Vladimir S. Levitskii, Vladimir O. Bolshakov, Maxim Yu. Maximov, Yury M. Koshtyal, Sergey I. Pavlov, Vladimir A. Tolmachev, Yuliya A. Zharova
Summary: A facile technique of semiconductor technology was developed to fabricate hybrid structures for creating sensitive sensors. The hybrid structures were created in one technological cycle, and numerical calculations and electromagnetic modeling were performed to study their properties. The experimental results showed reliable detection of methyl orange using these hybrid structures.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Anastasia Nenashkina, Semyon Koltsov, Olga Yu Orlova, Anna A. Nikitina, Demid A. Kirilenko, Daria Andreeva, Maria Blanco-Formoso, Nicolas Pazos-Perez, Ramon Alvarez-Puebla, Ekaterina Skorb
Summary: A new SERS detection platform is designed using the Liesegang rings formation process to achieve quantitative sensing of food quality, with complex silver and melamine-containing films showing high sensitivity even at relatively low concentrations of silver.
Article
Chemistry, Multidisciplinary
Yuan Nie, Congran Jin, John X. J. Zhang
Summary: This work integrates microfluidic devices, nanoparticle synthesis, and on-chip sensing for high-resolution biomolecular detection. Researchers explore how microfluidic geometry affects nanoparticle patterning for enhanced SERS-based sensing, providing insights into the rational design of continuous microfluidic systems for SERS applications. The integrated system demonstrates potential applications in label-free on-chip detection of biomolecules, promoting system integration, miniaturization, and on-site biological applications.
Review
Nutrition & Dietetics
Kuo-Chuan Hung, Min-Hsiang Chuang, Jen-Yin Chen, Chih-Wei Hsu, Chong-Chi Chiu, Ying-Jen Chang, Chia-Wei Lee, I-Wen Chen, Cheuk-Kwan Sun
Summary: This meta-analysis investigated the effects of intravenous vitamin C on mortality rate in critically ill patients. The analysis showed that patients who received vitamin C treatment had a lower risk of mortality compared to those who did not. However, further research is needed to confirm these findings. Subgroup analysis indicated that low dosage of vitamin C was associated with reduced mortality risk, while high dosage did not show significant benefits. The use of vasopressors and mechanical ventilation was shorter in the vitamin C group.
FRONTIERS IN NUTRITION
(2023)
Article
Chemistry, Physical
Isidro Badillo-Ramirez, Jose M. Saniger, Jurgen Popp, Dana Cialla-May
Summary: Dopamine (DA) detection using SERS technique showed reproducible spectra in c-AgNP medium, while a completely different SERS profile was observed in h-AgNP solution. DA oxidation and conversion to PDA were found under different pH conditions, with in situ PDA formation triggered by laser irradiation. Long laser exposure time led to the formation of stable AgNP-PDA composites.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Chemistry, Physical
Tiago Fernandes, Sara Fateixa, Marta Ferro, Helena I. S. Nogueira, Ana L. Daniel-da-Silva, Tito Trindade
Summary: The use of dendrimers in the controlled synthesis of Ag:Au hybrid nanostructures enhances SERS sensitivity to organic pollutants. Dendrimers play a crucial role as multipurpose ligands in the formation of hybrid nanostructures, improving stability and sensitivity. Interparticle plasmonic coupling templated by dendrimer macromolecules contributes to the high SERS sensitivity of the hybrid nanostructures.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Saeede Tafazoli, Muhammed Yusufoglu, Timucin Balkan, Sarp Kaya
Summary: We investigated the catalytic activity and C2 selectivity in electrochemical CO2 reduction reaction (CO2RR) on two electrodeposited Cu oxides with distinct morphologies and structures. The compact electrode exhibited higher faradaic efficiencies of C2 products (40%). A metastable phase (malachite) formed on electrode surfaces by consuming HCO3- was found to cause a shift in local pH, as observed through electrochemical surface-enhanced Raman spectroscopy (SERS). The presence of the malachite phase was strongly correlated with strongly-adsorbed CO on electrode surfaces, inhibiting dimerization and further reduction.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Sha Li, Zezhou Wang, Yunpeng Shao, Kai Zhang, Linyu Mei, Junyuan Wang
Summary: This study successfully constructed a highly active SERS substrate based on a three-dimensional silver nanostructure in a microfluidic channel, demonstrating its effective in situ detection capabilities for fluid media. The system showed excellent analysis performance in different concentrations of fluorescent dyes, with a detection limit as low as 10(-10) mol L-1, opening up a new pathway for the fabrication of high-performance microfluidic-SERS integrated sensor systems.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Huimin Sun, Xiuting Li, Ziyang Hu, Chenjie Gu, Dong Chen, Jun Wang, Bin Li, Tao Jiang, Xingfei Zhou
Summary: This research has successfully designed and fabricated a distinctive hydrophilic-hydrophobic SERS substrate utilizing paper and Ag nanowires, achieving goals such as enhanced SERS activity, microdroplet anchoring, and sample enrichment. It can be applied in environmental monitoring and in-situ detection effectively.
APPLIED SURFACE SCIENCE
(2021)
Article
Engineering, Biomedical
Vedran Nedelkovski, Orestis G. Andriotis, Karin Wieland, Christoph Gasser, Andreas Steiger-Thirsfeld, Johannes Bernardi, Bernhard Lendl, Michael L. Pretterklieber, Philipp J. Thurner
Summary: Bone tissue has unique mechanical properties due to its complex hierarchical structure. Testing of bone structures at the microscale using techniques like FIB and AFM has shown the importance of water for bone mechanics and the potential increase in bone fragility with age, linked to decreased energy dissipation.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Instruments & Instrumentation
Christopher K. Akhgar, Vanessa Nuernberger, Marlene Nadvornik, Victoria Ramos-Garcia, Isabel Ten-Domenech, Julia Kuligowski, Andreas Schwaighofer, Erwin Rosenberg, Bernhard Lendl
Summary: This study presents a novel method for determining the fatty acid composition of human milk using mid-infrared spectroscopy. By analyzing the absorbance spectra of pure milk fat recorded via attenuated total reflection Fourier transform infrared spectroscopy and combining the results with gas chromatography-mass spectrometry measurements, multivariate regression equations were established to predict fatty acid concentrations. The method achieved good predictions for various important fatty acid parameters, demonstrating its high accuracy.
APPLIED SPECTROSCOPY
(2022)
Article
Instruments & Instrumentation
Dominik Wacht, Mauro David, Borislav Hinkov, Hermann Detz, Andreas Schwaighofer, Bettina Baumgartner, Bernhard Lendl
Summary: The study presents the development of a mesoporous zirconia coating on ATR crystals to address the chemical stability issues of mesoporous silica in alkaline aqueous solutions, enabling in situ monitoring of organic pollutants. The coating exhibits strong chemical stability and high enrichment performance, with low detection limits for benzonitrile and valeronitrile.
APPLIED SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Alicja Dabrowska, Mauro David, Stephan Freitag, Aaron Maxwell Andrews, Gottfried Strasser, Borislav Hinkov, Andreas Schwaighofer, Bernhard Lendl
Summary: Mid-infrared chemical sensors based on quantum cascade technology were developed for broadband detection of aqueous samples targeting bovine milk proteins. The setup combined a tunable quantum cascade laser with a spectrally tailored in-house fabricated quantum cascade detector, showing similar performance to a high-end FTIR spectrometer. The study highlights the potential of quantum cascade detectors in next-generation MIR liquid-phase chemical sensors with low noise and high dynamic range.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Christopher K. Akhgar, Julian Ebner, Oliver Spadiut, Andreas Schwaighofer, Bernhard Lendl
Summary: In this study, an external cavity-quantum cascade laser-based mid-infrared spectrometer was used for in-line monitoring of proteins from preparative ion-exchange chromatography. Advanced background compensation strategies were implemented to obtain high-quality protein spectra, showing the potential to replace laborious off-line methods for protein monitoring.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Marwa R. El-Zahry, Marwa F. B. Ali
Summary: A novel voltammetric platform based on pencil graphite electrode (PGE) modification, containing bimetallic (NiFe) Prussian blue analogue nanopolygons decorated with electro-polymerized glyoxal polymer nanocomposites (p-DPG NCs@NiFe PBA Ns/PGE), was proposed. The electrochemical performance of the proposed sensor was investigated using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and square wave voltammetry (SWV). The method showed a good linear relationship, high correlation coefficient, and low detection limit for the determination of amisulpride (AMS) in human plasma and urine samples. The prepared sensing platform demonstrated outstanding reproducibility, stability, and reusability, and had promising applications for the simultaneous determination of AMS in the presence of co-administered COVID-19 drugs.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Shilpa Vijayakumar, Jeremy Rowlette, Andreas Schwaighofer, Bernhard Lendl
Summary: The stability of high-concentration protein formulations is a significant challenge in biopharmaceutical development. This study used laser-based mid-infrared spectroscopy to investigate the effect of protein concentration and the presence of sugars on the thermal denaturation of bovine serum albumin (BSA). The results showed that high BSA concentrations led to lower denaturation temperatures, while different sugars had both stabilizing and destabilizing effects.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
A. Catarina V. D. dos Santos, Nikolaus Hondl, Victoria Ramos-Garcia, Julia Kuligowski, Bernhard Lendl, Georg Ramer
Summary: Researchers have found that the application of conventional IR microscopy in the life sciences is limited due to the restrictions on spatial resolution. The use of AFM-IR technology allows for chemical analysis of biomolecules at the nanoscale, which can contribute to the investigation of nano and microscale biological processes.
ACS MEASUREMENT SCIENCE AU
(2023)
Article
Instruments & Instrumentation
Daniel-Ralph Hermann, Georg Ramer, Lisa Riedlsperger, Bernhard Lendl
Summary: Recently, high-throughput quantum cascade laser-based vibrational circular dichroism (QCL-VCD) technology has significantly reduced the measurement time for high-quality vibrational circular dichroism spectra. This study evaluated the feasibility of using QCL-VCD for chiral monitoring in a circulating system. The results showed that QCL-VCD demonstrated good sensitivity to both molar and enantiomeric excess (EE), making it suitable for high-resolution chiral monitoring in chemical processes.
APPLIED SPECTROSCOPY
(2023)
Article
Physics, Applied
E. V. Bergmann, G. V. B. Lukasievicz, B. Lendl, A. R. Sampaio, V. S. Zanuto, M. L. Baesso, L. C. Malacarne, N. G. C. Astrath
Summary: An all-optical photoinduced lensing method for exciting and monitoring acoustic waves in liquids is introduced in this article. The method utilizes a laser pulse to generate a localized temperature gradient, which launches pressure waves in the liquid at a nanosecond timescale. The refractive index change caused by acoustic and thermal effects can be sensed by a probe laser beam. The physical properties of the liquids can be quantitatively described based on the theoretical description of the intensity signal.
JOURNAL OF APPLIED PHYSICS
(2023)
Article
Chemistry, Analytical
Marwa R. El-Zahry, Jenny Jeehan M. Nasr, Nora H. Al-Shaalan, Amer F. Mahmoud
Summary: The influence of metal complexation on two ss-lactam antibiotics was investigated using SERS technique. It was found that metal complexation can promote the degradation and change the antibacterial activity of the antibiotics.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Plant Sciences
Jessica C. Huss, Sebastian J. Antreich, Martin Felhofer, Konrad Mayer, Michaela Eder, Ana Catarina Vieira Dias dos Santos, Georg Ramer, Bernhard Lendl, Notburga Gierlinger
Summary: The water caltrop develops unique woody fruits with unusually large seeds among aquatic plants. Hydrolyzable tannins flood the endocarp tissue during fruit development and lignin is integrated into the cell walls during maturation. The presence of ester linkages in the mature tissue suggests that gallotannins and their derivatives are cross-linked to other wall components, leading to unique cell-wall properties.
Article
Chemistry, Analytical
Ivan Rienda, Erika Moro, Alvaro Perez-Rubio, Ramon Trullenque-Juan, David Perez-Guaita, Bernhard Lendl, Julia Kuligowski, Jose V. Castell, Judith Perez-Rojas, Eugenia Pareja, Guillermo Quintas
Summary: Near-infrared and attenuated total reflectance-Fourier transform mid-infrared spectroscopy can be used for real-time quantitative assessment of liver steatosis, playing a crucial role in the success of liver transplantation surgery.
Article
Chemistry, Analytical
Ivan Rienda, Isabel Ten-Domenech, Erika Moro, Marta Moreno-Torres, Judith Perez-Rojas, Eugenia Pareja, Alvaro Perez-Rubio, Ramon Trullenque, Ramiro Jover, Bernhard Lendl, David Perez-Guaita, Julia Kuligowski, Jose V. Castell, Guillermo Quintas
Summary: The assessment of liver steatosis is crucial in hepatology and liver transplantation surgery. Current methods for evaluating steatosis are time-consuming, subjective, and lack reproducibility. Recent research has shown that infrared spectroscopy could be used for real-time quantification of steatosis during abdominal surgery. This study developed and validated digital image analysis methods that provide accurate and reproducible reference values for steatosis quantification, enhancing the performance of infrared spectroscopic models. A PLS model in the 1810-1052 cm(-1) region using first derivative ATR-FTIR spectra provided RMSECV = 0.99%.
Article
Biochemical Research Methods
Florian Pilat, Benedikt Schwarz, Bettina Baumgartner, Daniela Ristanic, Hermann Detz, Aaron M. M. Andrews, Bernhard Lendl, Gottfried Strasser, Borislav Hinkov
Summary: Quality control of liquids plays a crucial role in analytical chemistry, and the gold standard for measuring residual water in organic solvents and pharmaceutical applications is Karl Fischer titration. A high-performance lab-on-a-chip sensor based on mid-IR spectroscopy is proposed for real-time analysis of residual water concentration in isopropyl alcohol. Two experiments demonstrate its ability to detect water content with high sensitivity and rapid response time. The sensor achieves a limit of detection between 120 ppm and 150 ppm for the flow cell configuration and 1.5 x 10(-2)%(vol) to 19%(vol) in the in situ configuration.