Versican proteolysis predicts immune effector infiltration and post-transplant survival in myeloma

TIGIT immune checkpoint blockade restores CD8+T cell immunity against multiple myeloma

(2018) Camille Guillerey et al.   BLOOD

Autologous Transplantation for Newly Diagnosed Multiple Myeloma in the Era of Novel Agent Induction

(2018) Binod Dhakal et al.   JAMA Oncology

Myeloma-escape after stem cell transplantation is a consequence of T cell exhaustion and is prevented by TIGIT blockade

(2018) Simone A. Minnie et al.   BLOOD

IL-10 inducible CD8+ regulatory T-cells are enriched in patients with multiple myeloma and impact the generation of antigen-specific T-cells

(2018) Julian Plaumann et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Versican-Derived Matrikines Regulate Batf3–Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer

(2017) Chelsea Hope et al.   JOURNAL OF IMMUNOLOGY

Immunoregulatory roles of versican proteolysis in the myeloma microenvironment

(2016) C. Hope et al.   BLOOD

Multiple myeloma causes clonal T-cell immunosenescence: identification of potential novel targets for promoting tumour immunity and implications for checkpoint blockade

(2016) H Suen et al.   LEUKEMIA

Toll-like Receptor 2 Activation Promotes Tumor Dendritic Cell Dysfunction by Regulating IL-6 and IL-10 Receptor Signaling

(2015) Michael Tang et al.   Cell Reports

Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma

(2015) J. L. Jensen et al.   Cancer Immunology Research

T-cell Exhaustion in Multiple Myeloma Relapse after Autotransplant: Optimal Timing of Immunotherapy

(2015) D. J. Chung et al.   Cancer Immunology Research

The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis

(2014) Sumeda Nandadasa et al.   MATRIX BIOLOGY

Vaccination with Dendritic Cell/Tumor Fusions following Autologous Stem Cell Transplant Induces Immunologic and Clinical Responses in Multiple Myeloma Patients

(2013) J. Rosenblatt et al.   CLINICAL CANCER RESEARCH

Functionally Suppressive CD8 T Regulatory Cells Are Increased in Patients with Multiple Myeloma: A Cause for Immune Impairment

(2012) Karthick Raja Muthu Raja et al.   PLoS One