Article
Chemistry, Multidisciplinary
Nancy G. Bush, Mikiyas K. Assefa, Selin Bac, Shaama Mallikarjun Sharada, Megan E. Fieser
Summary: In the presence of (xantphos)RhCl catalyst, reaction of poly(vinyl chloride) (PVC) with triethyl silane in THF leads to partial reduction of PVC via hydrodechlorination. Increasing catalyst loading or using N,N-dimethylacetamide (DMA) as a solvent decreases the selectivity for hydrodechlorination. Reaction of PVC with sodium formate in THF affords excellent selectivity for hydrodechlorination along with complete PVC dechlorination, while higher catalyst loadings are required. In contrast, reaction of PVC with NaH in DMA exhibits good selectivity for dehydrochlorination and higher reaction rates.
MATERIALS HORIZONS
(2023)
Article
Environmental Sciences
Junhao Qin, Shuqing Zeng, Xi Wang, Chuxia Lin
Summary: A batch experiment was conducted to observe the liberation of micro- and nano-sized plastic particles and plastic additive-originated organic compounds from poly(vinyl chloride) under radiation-free ambient conditions. The detachment of plastic fragments from the PVC film surfaces was driven by autocatalyzed oxidative degradation, leading to intensified weathering.
Article
Chemistry, Multidisciplinary
Jiawei Wang, Guoqiao Wang, Tian Yu, Nengjie Ding, Meicheng Wang, Yao Chen
Summary: Biochar-modified TiO2 (C/TiO2) was prepared and showed improved photocatalytic performance for NH3-N removal from aqueous solutions. Characterization analyses confirmed the successful modification of biochar on TiO2 and the introduction of -COOH groups, which enhanced the photocatalytic performance. The composite C/TiO2 demonstrated a larger surface area and more pores, along with the presence of typical characteristic peaks of anatase-TiO2. NH3-N degradation mainly resulted in N-2 as the degradation product, indicating the potential of C/TiO2 for wastewater treatment and sewage sludge treatment.
Review
Environmental Sciences
Mostafa Hadei, Alireza Mesdaghinia, Ramin Nabizadeh, Amir Hossein Mahvi, Shahram Rabbani, Kazem Naddafi
Summary: This study systematically reviewed research articles on the photocatalytic degradation of pesticides using TiO2 nanoparticles and UV irradiation, with a total of 112 eligible articles included. Sixteen types of TiO2 were studied, with an average photodegradation efficiency of 71%. The study also discussed the impact of experimental conditions on photocatalytic activity, strategies to reduce energy requirements, and future research directions.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Tianxiang Deng, Shouhai Li, Xiaohua Yang, Lina Xu, Haiyang Ding, Mei Li
Summary: In this study, three types of internally-plasticized PVC materials were prepared by grafting castor oil onto the PVC chain with different isocyanates as intermediate bridges. The plasticizing ability and thermal stability of the materials were discussed. It was found that using hexamethylene diisocyanate (HDI) as the intermediate bridge had the best plasticizing effect, while using HDI trimer (THDI) optimized the thermal stability of the material.
Article
Multidisciplinary Sciences
Yi-Heng Lu, Zong-Lin Chen, Yu-Wei Lu
Summary: A PVC composite film doped with folic acid-modified titanium dioxide was synthesized to inhibit the agglomeration of nanotitanium dioxide. The results showed that the cohesiveness of the nanoparticles decreased after folic acid modification, leading to improved stability of PVC and reduced decomposition rate. The doped PVC film also suppressed the release of CO2 and enhanced the recovery of plasticizer.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Physical
Vahhab Soltaninejad, Ali Maleki
Summary: A new photocatalyst with efficient degradation capability and antibacterial properties was developed in this study. High degradation efficiency was achieved under visible light irradiation from LED lamp. Fourier-transform infrared, field-emission scanning electron microscopy, X-ray diffraction, and other analyses were utilized for characterizing the bionanocomposite.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Chemistry, Physical
Dandan Jin, Santosh Khanal, Shiai Xu
Summary: The study showed that OBPB/ZLDH could improve the thermal stability of PVC and accelerate the dechlorination and oxidation of PVC at low temperature.
APPLIED CLAY SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Rama Gaur, Syed Shahabuddin, Irfan Ahmad
Summary: This paper reports the preparation of a MAX phase-polyaniline nanocomposite as a photocatalyst for the degradation of methyl orange (MO) dye under solar light irradiation. The nanocomposite exhibits better performance than the pure polymer and MAX phase.
Article
Engineering, Environmental
Yi-heng Lu, Bing Wang, Meng-yao Xue, Yu-wei Lu
Summary: The study found that calcium metal soap and polyol additives are replacing organotin in PVC heat stabilizers, and investigated the thermal degradation and discoloration process of stabilized PVC using isothermal thermogravimetry. Results show that organotin prolongs the thermal oxidation degradation time of PVC and provides excellent heat resistance.
Article
Nanoscience & Nanotechnology
Tongrui Zhang, Shulong Zeng, Hao Jiang, Zeshan Li, Dongyu Bai, Yijun Li, Jianjun Li
Summary: By combining leather solid waste with poly(vinyl alcohol) and polyaniline, a new aerogel with high mechanical strength, flame retardancy, and EMI shielding performance was successfully prepared. The exposure of amino carboxyl groups through solid-state shear milling technology enhanced hydrogen bonding interactions, while the nitrogen elements in the waste contributed to flame retardancy. Additionally, a conductive polyaniline layer was polymerized on the surface, leading to impressive EMI shielding capabilities.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Mengmeng Li, Qin Cheng, Cheng Shen, Bin Hong, Yong Jiang, Yuxue Wei, Mengdie Cai, Jingshuai Chen, Song Sun
Summary: This study presents a novel photocatalytic air purification method using a ferroelectric strategy. The stretched PVDF layer enhances and stabilizes active adsorption sites, promoting the degradation of formaldehyde in a more efficient and stable way.
Article
Chemistry, Physical
Zhixiang Cui, Shengnan Tian, Xiaolong Liu, Qianting Wang, Sen Zeng, Junhui Si
Summary: The efficient elimination of toxic dye and Cr(VI) from wastewater by photocatalysis is achieved using a thermoplastic polyurethane (TPU)/titanium dioxide (TiO2)/polyaniline (PANI) fiber membrane. The membrane exhibits enhanced photocatalytic capacity, good stability, and easy recovery, making it a potential candidate for wastewater treatment.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Multidisciplinary
Jiaqi Chen, Jian Gao, Xiaoyang Liu, Pan Wang, Xue Yu, Feng Zhao, Yan Sun, Wei Feng, Qingyuan Wang
Summary: Degradation of organic pollutants, especially organic dyes and antibiotics, by semiconductor photocatalysts is an efficient strategy for wastewater treatment. TiO2 nanomaterials are considered promising due to their stability and availability. This research used oxalic acid to control the hydrolysis process of tetrabutyl titanate, leading to controllable crystalline phase transformation and reduced crystalline size of TiO2. The photocatalytic degradation performances were enhanced with increased ratio of oxalic acid to tetrabutyl titanate, attributed to improved dispersibility, increased specific surface area, reduced recombination rates of charge carriers, and decreased energy bands.
Article
Environmental Sciences
Qiang Wu, Jizhong Meng, Hang Yao, Rui Tang, Shoujun Yuan, Yulan Wang, Wei Wang, Haiping Luo, Zhen-Hu Hu
Summary: In this study, a floating TiO2/EVA photocatalyst was successfully synthesized using a simple thermal crosslinking procedure with ethylene-vinyl acetate copolymer (EVA) as the support material. The photocatalyst exhibited uniform TiO2 dispersion and high stability, leading to a significant enhancement in the degradation efficiency of Rhodamine B.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Materials Science, Multidisciplinary
Nazanin Amiryaghoubi, Marziyeh Fathi, Abolfazl Barzegari, Jaleh Barar, Hossein Omidian, Yadollah Omidi
Summary: The passage discusses the reasons for bone and cartilage defects, issues with autograft and allograft transplantations, and the application of tissue engineering. Graphene oxide and carbon nanotubes are highlighted for their potential in tissue engineering, particularly in cell proliferation, chondrogenic differentiation, and bone regeneration. The development of artificial three-dimensional biomaterials and the impact of polymer scaffolds based on GO and CNT on cellular behaviors in cartilage and bone regeneration are also explored. Additionally, the review touches on the importance of 3D hydrogel-based scaffolds, electrospinning, and 3D-printing methods in bone and cartilage tissue engineering.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Pharmacology & Pharmacy
Niloofar Babanejad, Umadevi Kandalam, Rand Ahmad, Yadollah Omidi, Hamid Omidian
Summary: The study investigated the abuse-deterrent properties and potential cytotoxicity of PEO after being heated at high temperatures. Results showed a significant loss in resistance features of the polymer and decreased cell viability when exposed to heated PEO. Findings emphasize the need for stricter regulations to ensure the safety and effectiveness of abuse-deterrent formulations under severe conditions.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Editorial Material
Pharmacology & Pharmacy
Hossein Omidian, Yadollah Omidi
Summary: Blockchain technology can significantly improve drug life cycle management and has potential advantages in various stages. Though its disruptive nature cannot solve problems overnight, the pharmaceutical and biotech industry will benefit in the long run.
DRUG DISCOVERY TODAY
(2022)
Article
Pharmacology & Pharmacy
Kwadwo Mfoafo, Young Kwon, Yadollah Omidi, Hossein Omidian
Summary: Poloxamers, also known as Pluronic(R), are amphiphilic polymers with thermo-responsive properties. They have been widely used in the pharmaceutical field for prolonging drug release, improving solubility, enhancing stability, and improving bioavailability. Their unique thermogelling property has also led to biomedical applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Hamieh Goshtasbi, Parvin Samadi Pakchin, Ali Movafeghi, Jaleh Barar, Ana M. Castejon, Hossein Omidian, Yadollah Omidi
Summary: The brain is highly sensitive to oxidative stress, and maintaining a balance between oxidants and antioxidants is crucial for its normal function. Imbalance between reactive oxygen species (ROS) and cellular mechanisms can lead to neurodegenerative disorders. Nuclear factor erythroid 2-related factor 2 (NRF2) is a key transcription factor that regulates the expression of antioxidant genes in response to oxidative stress. This review focuses on the mechanisms of generation of endogenous and exogenous oxidants and the role of antioxidants in neural cells through the NRF2-ARE signaling pathway.
NEUROCHEMISTRY INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Samaneh Alaei, Hossein Omidian
Summary: This short letter provides a brief overview of the importance of opioid overdose and the current approaches to combat it. It emphasizes the significance of naloxone, available dosage forms, and the unmet need for the development of safe and easily administrable naloxone formulations in emergency settings.
Article
Pharmacology & Pharmacy
Hossein Omidian, Niloofar Babanejad, Kwadwo Mfoafo, Charise Bertol, Yadollah Omidi
Summary: Geriatric polypharmacy is a complex issue involving multiple biological and pharmaceutical factors. This commentary highlights the potential safety concerns of inactive ingredients, such as polymers, in geriatric medications and calls for a reconsideration of safety standards.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Pharmacology & Pharmacy
Niloofar Babanejad, Umadevi Kandalam, Yadollah Omidi, Hossein Omidian
Summary: This study investigated the abuse-deterrent capability and toxicity of poly(ethylene oxide) (PEO) after thermal treatments. The findings showed that thermal manipulation led to the loss of deterrence performance and severe cell toxicity.
Review
Pharmacology & Pharmacy
Kwadwo Mfoafo, Rahul Mittal, Adrien Eshraghi, Yadollah Omidi, Hossein Omidian
Summary: The management of inner ear disorders is hindered by challenges in delivering drug molecules to the affected cells. Systemic therapy often results in sub-optimal concentration due to the blood-labyrinth barrier (BLB), while local drug delivery methods face issues with drainage. The use of hydrogels to deliver drugs to the inner ear offers significant potential, and this article discusses the impact of such formulations.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Review
Pharmacology & Pharmacy
Hossein Omidian, Jafar Razmara, Sepideh Parvizpour, Hamed Tabrizchi, Yosef Masoudi-Sobhanzadeh, Yadollah Omidi
Summary: The life cycle of a drug starts from its discovery and ends when it is disposed. Various entities such as drug discovery companies, manufacturers, regulatory agencies, suppliers, pharmacies, patients, and healthcare providers are involved in this process. Transparency, traceability, automation, and data security play crucial roles in ensuring effective and safe transactions among all parties. However, challenges like scalability, energy consumption, regulations, standards, and complexity hinder the adoption of new technology that can fulfill these requirements. This article highlights how blockchain technology can track, accelerate, and enhance the efficiency of complex operations like pharmaceutical development.
DRUG DISCOVERY TODAY
(2023)
Article
Pharmacology & Pharmacy
Kwadwo Mfoafo, Yadollah Omidi, Hossein Omidian
Summary: Thermoresponsive polymers have been widely used for the development of stimuli-responsive drug formulations in various routes of administration. However, their use has been limited by obstacles such as high polymer concentration, wide gelation temperature, low gel strength, poor mucoadhesiveness, and short retention. In-situ thermoresponsive mucoadhesive hydrogel blends or hybrids have been suggested as a solution to improve drug bioavailability and efficacy. This article highlights the development and assessment of such hydrogels in different administration routes.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Review
Engineering, Biomedical
Parvin Shokrollahi, Yadollah Omidi, Luigi X. Cubeddu, Hossein Omidian
Summary: Cardiovascular diseases, including myocardial infarction, are a major global burden and the leading cause of death. Cell-based tissue engineering and regeneration may be the only viable option for restoring normal heart function since damaged cardiac tissue cannot self-repair. Various techniques, such as the incorporation of cells into conductive polymers (CPs) and biomaterials, have been used to transport cells to damaged cardiac tissues. The success of tissue engineering for the damaged heart depends on factors like cell source, growth factors, and scaffolds.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Hamed Sadighian, Zahra Mohamadnia, Ebrahim Ahmadi
Summary: Emulsions formed by water in crude oil need to be broken before refining processes. Novel derivatives of imidazolium ionic liquids (ILs) containing triazole moiety [SIm-TazCn][Br] were synthesized and grafted onto cellulose (CEL) to prepare eco-friendly demulsifiers for breaking water-in-oil (W/O) emulsions. The CEL[SIm-TazC6][Br] derivative showed a good dehydration efficiency (DE) of 79% at 4000 ppm after 5 min, which increased to 82% after 24 h. The interfacial tension (IFT) of CEL[SIm-TazC6][Br] with a shorter alkyl chain at 4000 ppm after 24 h was measured to be the minimum value of 16.3 mN/m.
Review
Pharmacology & Pharmacy
Kwadwo Mfoafo, Rahul Mittal, Adrien Eshraghi, Yadollah Omidi, Hossein Omidian
Summary: Thiolated polymers, known as thiomers, have unique mucoadhesive properties and can form strong covalent bonds with cysteine-rich subdomains of mucus glycoproteins. This makes them suitable for drug delivery systems (DDSs) for dry mucosal surface diseases. Thiomers offer higher adhesion and retention time compared to non-thiolated polymers, leading to increased bioavailability and reduced patient noncompliance. They can also inhibit enzymes, increase permeability, and protect protein and peptide drugs from digestive enzymes. Thiolated polymers have potential applications in adhesion, controlled drug release, and tissue engineering.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Review
Polymer Science
Hossein Omidian, Sumana Dey Chowdhury
Summary: Conductive hydrogels are attracting significant attention due to their diverse applications in healthcare monitoring, wearable sensors, electronic devices, soft robotics, energy storage, and human-machine interfaces. Researchers are focusing on improving properties such as sensitivity, mechanical strength, electrical performance at low temperatures, stability, antibacterial properties, and conductivity. Composite materials, including nanoparticles, nanowires, polymers, and ionic liquids, are being incorporated to enhance conductivity and mechanical strength. Biocompatibility and biosafety are emphasized for safe integration with biological tissues. Conductive hydrogels exhibit unique properties such as stretchability, self-healing, wet adhesion, anti-freezing, transparency, UV-shielding, and adjustable mechanical properties, making them suitable for specific applications. Researchers aim to develop multifunctional hydrogels with antibacterial characteristics, self-healing capabilities, transparency, UV-shielding, gas-sensing, and strain-sensitivity.
