Review
Anesthesiology
Benjamin Siddall, Adrian Ram, Matthew D. Jones, John Booth, Diana Perriman, Simon J. Summers
Summary: This systematic review and meta-analysis evaluated the effect of combining pain neuroscience education (PNE) with exercise therapy for chronic musculoskeletal pain. The findings suggest that combining PNE and exercise leads to greater short-term improvements in pain, disability, kinesiophobia, and pain catastrophizing compared to exercise alone.
Review
Oncology
Ana Maria Gonzalez-Martin, Ivan Aguilera-Garcia, Yolanda Castellote-Caballero, Yulieth Rivas-Campo, Antonio Bernal-Suarez, Agustin Aibar-Almazan
Summary: Cancer pain is a crucial aspect of patients' survival and quality of life, and pain education programs for cancer patients can effectively reduce pain intensity in the medium term. However, no significant improvement was observed in the worst reported pain or overall quality of life of patients. Further research is needed to evaluate the effects of such interventions on the oncology population.
Review
Behavioral Sciences
Joaquin Salazar-Mendez, Rodrigo Nunez-Cortes, Luis Suso-Marti, Ivana Leao Ribeiro, Maria Garrido-Castillo, Jose Gacitua, Guillermo Mendez-Rebolledo, Carlos Cruz-Montecinos, Ruben Lopez-Bueno, Joaquin Calatayud
Summary: The aim of this study was to examine the moderator effect of duration of pain neuroscience education (PNE) on changes in psychosocial variables in patients with chronic musculoskeletal pain. A meta-analysis of 23 studies involving 2352 patients showed that longer duration of PNE had a significant effect on pain neurophysiology knowledge, anxiety symptoms, catastrophizing, and kinesiophobia. Additionally, a dose of 100, 200, and 400 minutes of PNE was estimated to exceed the minimum clinically important difference for kinesiophobia, anxiety symptoms, and catastrophizing.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Review
Neurosciences
Ferran Cuenca-Martinez, Luis Suso-Marti, Joaquin Calatayud, Francisco Jose Ferrer-Sargues, Vicente Munoz-Alarcos, Patricio Alba-Quesada, Gemma Bivia-Roig
Summary: Pain neuroscience education (PNE) has been extensively studied in the field of physical therapy, but its effectiveness remains controversial. This umbrella review found that adding PNE-based intervention to other treatments can lead to greater clinical improvements in patients with chronic musculoskeletal pain, particularly in reducing the influence of psychosocial variables. However, studies testing the effectiveness of PNE alone did not show statistically significant improvements in pain intensity, disability levels, or psychosocial variables.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Clinical Neurology
Lorenzo Bonatesta, Juan D. Ruiz-Cardenas, Luis Fernandez-Azorin, Juan J. Rodriguez-Juan
Summary: The study found that pain science education plus exercise therapy has a certain improvement effect on the management of symptoms in patients with chronic nonspecific spinal pain. However, further investigation and research are needed to confirm its effectiveness due to the limited number of studies and short follow-up periods.
Review
Clinical Neurology
James A. Watson, Cormac G. Ryan, Greg Atkinson, Philip Williamson, Dominic Ellington, Robbie Whittle, John Dixon, Denis J. Martin
Summary: Pain neuroscience education is a method used in managing chronic musculoskeletal pain, and quantifying inter-individual differences in treatment response is important for optimizing effectiveness. Evaluating response variance can help tailor PNE to specific individuals.
Review
Medicine, General & Internal
Seungwoo Shin, Hyunjoong Kim
Summary: Pain neuroscience education has a short-term carryover effect on pain intensity and pain cognition in individuals with chronic low back pain (CLBP), and a long-term carryover effect on kinesiophobia.
MEDICINA-LITHUANIA
(2023)
Review
Anesthesiology
Kasper Bulow, Kasper Lindberg, Henrik Bjarke Vaegter, Carsten Bogh Juhl
Summary: Pain Neurophysiology Education (PNE) has small to moderate effects on pain, disability, and psychological distress in musculoskeletal pain (MSKP) patients, with a more significant impact on psychological distress. The intervention shows positive effects on pain at both post-intervention and long-term time points, while the effects on disability and psychological distress vary depending on the time point. The overall quality of evidence supports the safety and efficacy of PNE for MSKP patients.
Review
Orthopedics
Javier Martinez-Calderon, Emma Kwan-Yee Ho, Paulo Henrique Ferreira, Cristina Garcia-Munoz, Olga Villar-Alises, Javier Matias-Soto
Summary: In this overview of systematic reviews with meta-analysis, the effects of pain neuroscience education delivered alone or combined with other interventions for chronic pain were evaluated. The results showed that pain neuroscience education had some positive effects, but there were inconsistencies and a lack of high-quality evidence. Overall, more research is needed to improve the quality and provide clearer clinical recommendations.
JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY
(2023)
Review
Anesthesiology
Luis Suso-Marti, Ferran Cuenca-Martinez, Patricio Alba-Quesada, Vicente Munoz-Alarcos, Aida Herranz-Gomez, Clovis Varangot-Reille, Fernando Dominguez-Navarro, Jose Casana
Summary: Pain neuroscience education (PNE) has a positive effect on patients with fibromyalgia, reducing pain intensity and fibromyalgia impact. The effectiveness is more pronounced in face-to-face interventions.
Review
Medicine, General & Internal
Javier Picanol Parraga, Aida Castellanos
Summary: Chronic pain is not only a symptomatic manifestation but also a pathological condition with profound socioeconomic implications. Non-pharmacological treatments are being considered due to the persistently high prevalence of chronic pain despite medical interventions. However, there are misconceptions and over-simplifications in the cognitive understanding of pain, highlighting the need for a re-evaluation of nociception and pain perception and emphasizing the importance of understanding the complexity of pain.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Mia T. Minen, Ramisha Aymon, Ishah Yusaf, Khushalee Oza, Jane Ekhtman, Aarti Katara, Naomi Lebowitz, Caitlin Plovnick
Summary: A systematic review of existing undergraduate neurology pipeline programs found that these programs successfully inspire interest in a career in neurology among undergraduate students, providing exposure to relevant opportunities and classroom enrichment.
FRONTIERS IN MEDICINE
(2023)
Article
Anesthesiology
Elizabeth Lane, John S. Magel, Anne Thackeray, Tom Greene, Nora F. Fino, Emilio J. Puentedura, Adriaan Louw, Daniel Maddox, Julie M. Fritz
Summary: Pain neuroscience education did not result in significant functional changes in patients with chronic spinal pain compared to usual care, but did show significant improvement in pain self-efficacy.
Article
Biochemistry & Molecular Biology
Jeongkeun Song, Hyunjoong Kim, Jihye Jung, Seungwon Lee
Summary: This study aimed to demonstrate the therapeutic effect of combining soft-tissue mobilization (STM) with pain neuroscience education (PNE) for chronic nonspecific low back pain with central sensitization. The results showed that the group receiving STM plus PNE had significant improvement in pain intensity, central sensitization, pressure pain, pain cognition, and disability compared to the group receiving only STM.
Article
Health Care Sciences & Services
Ki-Sang Kim, Jungae An, Ju-O Kim, Mi-Young Lee, Byoung-Hee Lee
Summary: This study investigated the effects of pain neuroscience education combined with lumbar stabilization exercises on female patients with chronic low back pain. The results showed that the combination of pain neuroscience education and lumbar stabilization exercises significantly improved muscle strength and reduced pain compared to lumbar stabilization exercises alone.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Rehabilitation
Anna L. Hatton, Katrina Williams, Mark D. Chatfield, Sheree E. Hurn, Jayishni N. Maharaj, Elise M. Gane, Thomas Cattagni, John Dixon, Keith Rome, Graham Kerr, Sandra G. Brauer
Summary: This study investigated the immediate effects of wearing novel sensory-stimulating textured insoles on balance and gait in people with multiple sclerosis (pwMS). The results showed that wearing textured insoles reduced center of pressure (CoP) movement during standing and did not consistently improve gait compared to smooth insoles or shoes only. Walking barefoot led to poorer gait performance. The study suggests that stimulating the foot with texture could be a potential new treatment option for balance rehabilitation in pwMS, but further research is needed to determine who would benefit the most from textured insoles.
DISABILITY AND REHABILITATION
(2023)
Review
Health Care Sciences & Services
Rachel Arnott, Victoria Park, Nicola Rhind, Kay Cooper
Summary: This review explored the experiences and perceptions of adults with chronic non-cancer pain who participated in peer-support interventions. The findings provide valuable insights for developing and implementing peer-support interventions for adults with chronic non-cancer pain. Further research is needed to explore intervention format, length, and frequency of contact, as well as to include perspectives from low- and middle-income countries.
JBI EVIDENCE SYNTHESIS
(2023)
Article
Nutrition & Dietetics
Oliver J. Perkin, Yung-Chih Chen, Drusus A. Johnson, Joel E. Thomas, Greg Atkinson, James A. Betts, Javier T. Gonzalez
Summary: Ingesting polymerized polyphenols (PP) alone at doses <150 mg does not significantly alter early-phase postprandial triacylglycerol concentrations in healthy adults. However, the addition of caffeine and catechins to PP lowers postprandial glucose and insulin concentrations. Therefore, the effects of PP on postprandial lipemia are limited, but the addition of caffeine and catechins may have a regulatory effect on postprandial blood glucose and insulin.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Review
Sport Sciences
Anastasia Vladimirovna Pavlova, Joanna S. C. Shim, Rachel Moss, Colin Maclean, David Brandie, Laura Mitchell, Leon Greig, Eva Parkinson, Lyndsay Alexander, Victoria Tzortziou Brown, Dylan Morrissey, Kay Cooper, Paul A. Swinton
Summary: This systematic review and meta-analysis investigated the moderating effects of resistance exercise dose components including intensity, volume and frequency for the management of common tendinopathies. The results indicated that higher intensity therapies and lower frequency therapies have better efficacy in tendinopathy management, while the association between training volume and effect sizes was minimal and inconsistent.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Review
Endocrinology & Metabolism
J. D. Watkins, S. Carter, G. Atkinson, F. Koumanov, J. A. Betts, J. J. Holst, J. T. Gonzalez
Summary: This systematic review aims to investigate the effect of type 2 diabetes (T2D) on GLP-1 secretion and explore potential moderators. The findings show that there is minimal and inconsistent difference in GLP-1 secretion between individuals with T2D and without T2D.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2023)
Review
Rehabilitation
Katharine Johnson, Paul Swinton, Anastasia Pavlova, Kay Cooper
Summary: This scoping review highlights the issues related to manual patient handling by healthcare practitioners, indicating the presence of awkward postures and high loads during handling tasks. The majority of the studies focused on observational research, primarily investigating nurses in hospitals or laboratory settings. There is a need for more research on other healthcare professionals and the biomechanics involved in therapeutic handling.
Review
Rehabilitation
J. Shim, A. V. Pavlova, R. A. Moss, C. MacLean, D. Brandie, L. Mitchell, L. Greig, E. Parkinson, L. Greig, V. Tzortziou Brown, D. Morrissey, L. Alexander, K. Cooper, P. A. Swinton
Summary: The study aims to synthesize exercise therapy intervention data regarding patient rating outcomes for the management of tendinopathy. Through a systematic review and meta-analysis of randomized controlled trials, exercise therapy interventions and patient rating outcomes were investigated. The results show that patients have a high level of satisfaction and perceive positive effects from exercise therapy.
Article
Nutrition & Dietetics
Javier T. Gonzalez, Alan M. Batterham, Greg Atkinson, Dylan Thompson
Summary: The idea of increasing physical activity directly adding to total energy expenditure (TEE) in humans is challenged by the energy constrained hypothesis. Evidence supporting this hypothesis is limited due to various methodological issues, and future studies should address these limitations by using randomized controlled trials. The available evidence suggests that increasing physical activity mostly has an additive effect on TEE, although some energy remains unaccounted for, and the degree of energy balance may further moderate this effect.
ADVANCES IN NUTRITION
(2023)
Article
Sport Sciences
Garrison Draper, Greg Atkinson, Paul Chesterton, Matthew Portas, Matthew Wright
Summary: The study aimed to investigate the correlations between environmental temperature and performance changes in elite soccer competitions. The results showed that there were small correlations between temperature measures and performance, with a minimal impact.
JOURNAL OF SPORTS SCIENCES
(2023)
Review
Sport Sciences
Nathan Liddle, Jonathan M. Taylor, Paul Chesterton, Greg Atkinson
Summary: Exercise-based injury prevention programmes have the potential to reduce the risk of injury in adult recreational athletes. However, the effects of these programmes are still uncertain due to limited sample size, high heterogeneity, and potential small study effects. More large-scale studies are needed to determine the effectiveness of exercise-based injury prevention programmes in adult recreational athletes.
Review
Sport Sciences
Leon Greig, Rodrigo R. Aspe, Andy Hall, Paul Comfort, Kay Cooper, Paul A. Swinton
Summary: This study examined the predictive validity of load-velocity relationships for estimating 1RMs. Through meta-analysis and evaluation of 26 studies, it was found that load-velocity relationships tend to overestimate 1RMs, but can still be useful for monitoring training progress and providing high-frequency estimates. It is recommended to select the appropriate modeling approach based on practical requirements.
Article
Medicine, Research & Experimental
Donna Wynne, Kay Cooper
Summary: This study explored student perceptions of running a student-led neurological rehabilitation clinic in the UK. The findings showed that this model positively influenced student experience and skill development in terms of learning environment, clinical skills, leadership, and autonomy. Further research is needed to examine if these findings are applicable in other countries.
Review
Radiology, Nuclear Medicine & Medical Imaging
Casey Farrell, Kay Cooper, Simon Hayward, Craig Walker
Summary: This scoping review aimed to map the evidence base regarding the use of lung ultrasonography (LUS) to assess cardiac surgery patients. The results suggest that standardized protocols for the use of LUS are yet to be widely adopted, highlighting the need for further work in this area.
JOURNAL OF DIAGNOSTIC MEDICAL SONOGRAPHY
(2023)
Review
Sport Sciences
Paul A. Swinton, Joanna S. C. Shim, Anastasia Vladimirovna Pavlova, Rachel Moss, Colin Maclean, David Brandie, Laura Mitchell, Leon Greig, Eva Parkinson, Victoria Tzortziou Brown, Dylan Morrissey, Lyndsay Alexander, Kay Cooper
Summary: This study conducted a systematic review with meta-analysis to explore the effect size distributions of exercise therapies for different tendinopathies and outcome domains. The results showed that the effect sizes varied across outcome domains but were similar across tendinopathies. Threshold values for different outcome measures were determined, which can guide interpretation and further research.
BMJ OPEN SPORT & EXERCISE MEDICINE
(2023)
Review
Public, Environmental & Occupational Health
Mark Parkinson, Cormac Ryan, Leah Avery, Annette Hand, Bhanu Ramaswamy, Julie Jones, Fiona Lindop, Monty Silverdale, Katherine Baker, Jenni Naisby
Summary: This scoping review aims to examine the available evidence on pain management in Parkinson's, with a focus on behavioural interventions, resources, and professional support for self-management. The review will analyze both quantitative and qualitative data to identify the characteristics of support for pain management, orientation of approaches, and behavior change components and outcomes.
INTERNATIONAL JOURNAL FOR EQUITY IN HEALTH
(2023)