Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 84, Issue 4, Pages 2200-2208Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b03193
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21701148, 21471134, 21571158]
- Key Research Project of University of Henan Province [19zx004]
- Universities in Henan Province [17A150053]
Ask authors/readers for more resources
A Pd-catalyzed ring-opening reaction of 2H-azirines with carboxylic acids was developed. This reaction undergoes nucleophilic addition between 2,3-diaryl-2H-azirines and carboxylic acids followed by C-N single-bond cleavage and a subsequent thermal rearrangement. This method enables the rapid construction of valuable alpha-amido ketone derivatives with high atomic efficiency and superb functional group tolerance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
