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Preoperative surgical planning of glioma: limitations and reliability of fMRI and DTI tractography

JOURNAL OF NEUROSURGICAL SCIENCES (2019)

Journal

JOURNAL OF NEUROSURGICAL SCIENCES

Volume 63, Issue 2, Pages 127-134

Publisher

EDIZIONI MINERVA MEDICA

DOI: 10.23736/S0390-5616.18.04597-6

Keywords

Glioma; Brain mapping; Magnetic resonance imaging; Diffusion tensor imaging

Categories

Clinical Neurology Surgery

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Abstract

Brain mapping techniques (intraoperative neurophysiology and neuropsychology) represent the gold standard in glioma surgery, and particularly in glioma resection. Since the introduction of MRI in the clinical practice, several advanced applications have been developed, like functional MRI (fMRI) and diffusion imaging-based tractography (DTI), which both have an application in glioma surgery. fMRI allows to identify cortical areas related to a specific function, DTI allows to reconstruct a model of the sub-cortical connectivity. This paper describes the clinical application of fMRI and DTI, enlightening sensitivity and specificity in comparison to gold standard and underlining their limitations in surgical decision making.

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