A novel neurotherapeutic for multiple sclerosis, ischemic injury, methamphetamine addiction, and traumatic brain injury

Uncovering the Rosetta Stone: Report from the First Annual Conference on Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical

(2018) Gregory J. Bix et al.   Translational Stroke Research

Increased CD74 binding and EAE treatment efficacy of a modified DRα1 molecular construct

(2018) Roberto Meza-Romero et al.   METABOLIC BRAIN DISEASE

Sex-dependent treatment of chronic EAE with partial MHC class II constructs

(2017) Gil Benedek et al.   Journal of Neuroinflammation

DRα1-MOG-35-55 treatment reduces lesion volumes and improves neurological deficits after traumatic brain injury

(2017) Liu Yang et al.   METABOLIC BRAIN DISEASE

Upregulation of CD74 and its potential association with disease severity in subjects with ischemic stroke

(2017) Liu Yang et al.   NEUROCHEMISTRY INTERNATIONAL

Various Cell Populations Within the Mononuclear Fraction of Bone Marrow Contribute to the Beneficial Effects of Autologous Bone Marrow Cell Therapy in a Rodent Stroke Model

(2016) Bing Yang et al.   Translational Stroke Research

Regulatory T Cells in Post-stroke Immune Homeostasis

(2016) Arthur Liesz et al.   Translational Stroke Research

Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH)

(2016) Etienne Atangana et al.   Translational Stroke Research

Emerging Roles for the Immune System in Traumatic Brain Injury

(2016) Celia A. McKee et al.   Frontiers in Immunology

Estrogen receptors regulate innate immune cells and signaling pathways

(2015) Susan Kovats   CELLULAR IMMUNOLOGY

HLA-DRα1-mMOG-35-55 treatment of experimental autoimmune encephalomyelitis reduces CNS inflammation, enhances M2 macrophage frequency, and promotes neuroprotection

(2015) Gil Benedek et al.   Journal of Neuroinflammation

Chronic Systemic Immune Dysfunction in African-Americans with Small Vessel-Type Ischemic Stroke

(2015) Candice M. Brown et al.   Translational Stroke Research

The Role of Arginase 1 in Post-Stroke Immunosuppression and Ischemic Stroke Severity

(2015) Ashley B. Petrone et al.   Translational Stroke Research

The protective role of prosaposin and its receptors in the nervous system

(2014) Rebecca C. Meyer et al.   BRAIN RESEARCH

Short Communication Huwe1 as a therapeutic target for neural injury

(2014) J. Zhou et al.   GENETICS AND MOLECULAR RESEARCH

Macrophages: A double-edged sword in experimental autoimmune encephalomyelitis

(2014) Zhilong Jiang et al.   IMMUNOLOGY LETTERS

World Stroke Organization Global Stroke Services Guidelines and Action Plan

(2014) Patrice Lindsay et al.   International Journal of Stroke

The Role of the Spleen in Ischemic Stroke

(2014) Keith R Pennypacker et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

HLA-DR 1 Constructs Block CD74 Expression and MIF Effects in Experimental Autoimmune Encephalomyelitis

(2014) R. Meza-Romero et al.   JOURNAL OF IMMUNOLOGY

Macrophages and CNS remyelination

(2014) Veronique E. Miron et al.   JOURNAL OF NEUROCHEMISTRY

Myocilin Is Involved in NgR1/Lingo-1-Mediated Oligodendrocyte Differentiation and Myelination of the Optic Nerve

(2014) H. S. Kwon et al.   JOURNAL OF NEUROSCIENCE

Molecular dialogs between the ischemic brain and the peripheral immune system: Dualistic roles in injury and repair

(2014) Chengrui An et al.   PROGRESS IN NEUROBIOLOGY

An Update on Inflammation in the Acute Phase of Intracerebral Hemorrhage

(2014) Sheng Chen et al.   Translational Stroke Research

Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration

(2013) Yongcheol Cho et al.   CELL

Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects

(2013) Gil Benedek et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A novel HLA-DRα1-MOG-35-55 construct treats experimental stroke

(2013) Gil Benedek et al.   METABOLIC BRAIN DISEASE

Partial MHC/Neuroantigen Peptide Constructs: A Potential Neuroimmune-Based Treatment for Methamphetamine Addiction

(2013) Jennifer M. Loftis et al.   PLoS One

Forecasting the Future of Stroke in the United States: A Policy Statement From the American Heart Association and American Stroke Association

(2013) B. Ovbiagele et al.   STROKE

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

(2012) Alok Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration

(2012) Yongcheol Cho et al.   EMBO JOURNAL

Multiple sclerosis: Neuroprotective alliance of estrogen–progesterone and gender

(2012) Markus Kipp et al.   FRONTIERS IN NEUROENDOCRINOLOGY

A novel regulatory pathway for autoimmune disease: Binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance

(2012) Arthur A. Vandenbark et al.   JOURNAL OF AUTOIMMUNITY

A Transient Decrease in Spleen Size Following Stroke Corresponds to Splenocyte Release into Systemic Circulation

(2012) Hilary A. Seifert et al.   Journal of Neuroimmune Pharmacology

Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes

(2012) Ankit Shah et al.   Journal of Neuroinflammation

Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival

(2012) T. Zurashvili et al.   MOLECULAR AND CELLULAR BIOLOGY

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Inflammation after trauma: Microglial activation and traumatic brain injury

(2011) Anil F. Ramlackhansingh et al.   ANNALS OF NEUROLOGY

Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity

(2011) Xuefang Ren et al.   METABOLIC BRAIN DISEASE

Recombinant Τ Cell Receptor Ligands: Immunomodulatory, Neuroprotective and Neuroregenerative Effects Suggest Application as Therapy for Multiple Sclerosis

(2011) Halina Offner et al.   REVIEWS IN THE NEUROSCIENCES

Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis

(2010) Sushmita Sinha et al.   JOURNAL OF NEUROIMMUNOLOGY

RTL therapy for multiple sclerosis: A Phase I clinical study

(2010) Halina Offner et al.   JOURNAL OF NEUROIMMUNOLOGY

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration

(2010) Joanna Mikita et al.   Multiple Sclerosis Journal

Global and local morphometric differences in recently abstinent methamphetamine-dependent individuals

(2010) Daniel L. Schwartz et al.   NEUROIMAGE

Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum

(2010) D. D'Arca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abuse of Amphetamines and Structural Abnormalities in the Brain

(2009) Steven Berman et al.   Annals of the New York Academy of Sciences

Cytokine Switch and Bystander Suppression of Autoimmune Responses to Multiple Antigens in Experimental Autoimmune Encephalomyelitis by a Single Recombinant T-Cell Receptor Ligand

(2009) S. Sinha et al.   JOURNAL OF NEUROSCIENCE

Monocytes Are Major Players in the Prognosis and Risk of Infection After Acute Stroke

(2009) Xabier Urra et al.   STROKE

Requirement of 3-Phosphoinositide-Dependent Protein Kinase-1 for BDNF-Mediated Neuronal Survival

(2008) G. Kharebava et al.   JOURNAL OF NEUROSCIENCE

Stroke

(2008) Geoffrey A Donnan et al.   LANCET

Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis

(2008) Eva Herrero-Herranz et al.   NEUROBIOLOGY OF DISEASE

Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression

(2008) H. Offner et al.   NEUROSCIENCE

Cortical activation during delay discounting in abstinent methamphetamine dependent individuals

(2008) William F. Hoffman et al.   PSYCHOPHARMACOLOGY