Endogenous transient receptor potential ankyrin 1 and vanilloid 1 activity potentiates glutamatergic input to spinal lamina I neurons in inflammatory pain

The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions

(2018) Jinjun Chen et al.   Cell Reports

Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons

(2018) Li Wang et al.   JOURNAL OF NEUROCHEMISTRY

A TRP channel trio mediates acute noxious heat sensing

(2018) Ine Vandewauw et al.   NATURE

Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial

(2017) Michael S Avidan et al.   LANCET

Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons

(2017) Qiang Wang et al.   NEURON

Bortezomib induces neuropathic pain through protein kinase C-mediated activation of presynaptic NMDA receptors in the spinal cord

(2017) Jing-Dun Xie et al.   NEUROPHARMACOLOGY

Nociceptor Sensory Neuron–Immune Interactions in Pain and Inflammation

(2017) Felipe A. Pinho-Ribeiro et al.   TRENDS IN IMMUNOLOGY

Peripheral and spinal TRPA1 channels contribute to formalin-induced long-lasting mechanical hypersensitivity

(2017) Vladimir A Martínez-Rojas et al.   Journal of Pain Research

PresynapticN-Methyl-d-aspartate (NMDA) Receptor Activity Is Increased Through Protein Kinase C in Paclitaxel-induced Neuropathic Pain

(2016) Jing-Dun Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity

(2016) Laurie B. Schenkel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain

(2016) Lingyong Li et al.   Cell Reports

Contribution of Transient Receptor Potential Ankyrin 1 to Chronic Pain in Aged Mice With Complete Freund's Adjuvant-Induced Arthritis

(2014) Sheldon R. Garrison et al.   Arthritis & Rheumatology

Calcineurin inhibitor induces pain hypersensitivity by potentiating pre- and postsynaptic NMDA receptor activity in spinal cords

(2013) Shao-Rui Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

5,6-EET Is Released upon Neuronal Activity and Induces Mechanical Pain Hypersensitivity via TRPA1 on Central Afferent Terminals

(2012) M. Sisignano et al.   JOURNAL OF NEUROSCIENCE

TRPA1 Mediates Mechanical Sensitization in Nociceptors during Inflammation

(2012) Richard C. Lennertz et al.   PLoS One

Inflammatory Pain Unmasks Heterosynaptic Facilitation in Lamina I Neurokinin 1 Receptor-Expressing Neurons in Rat Spinal Cord

(2011) C. Torsney   JOURNAL OF NEUROSCIENCE

A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis

(2010) Elizabeth S. Fernandes et al.   ARTHRITIS AND RHEUMATISM

Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel

(2010) Alexander Staruschenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents

(2010) Amol M. Patwardhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Opioid-Induced Long-Term Potentiation in the Spinal Cord Is a Presynaptic Event

(2010) H.-Y. Zhou et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent Ubiquitination of GluA1 Mediates a Distinct AMPA Receptor Endocytosis and Sorting Pathway

(2010) L. A. Schwarz et al.   JOURNAL OF NEUROSCIENCE

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones

(2009) Paul J Wrigley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression of transient receptor potential ankyrin 1 (TRPA1) in the rat trigeminal sensory afferents and spinal dorsal horn

(2009) Yun Sook Kim et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Plasticity and emerging role of BKCachannels in nociceptive control in neuropathic pain

(2009) Shao-Rui Chen et al.   JOURNAL OF NEUROCHEMISTRY

N-Methyl-d-aspartate receptor (NMDAR) independent maintenance of inflammatory pain

(2009) Amanda R. Weyerbacher et al.   PAIN

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn

(2008) Hong-Yi Zhou et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of Prolonged Presynaptic Ca2+ Signaling and Glutamate Release Induced by TRPV1 Activation in Rat Sensory Neurons

(2008) Y. V. Medvedeva et al.   JOURNAL OF NEUROSCIENCE

Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

(2008) D. A. Andersson et al.   JOURNAL OF NEUROSCIENCE

Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal

(2008) T. E. Taylor-Clark et al.   JOURNAL OF PHYSIOLOGY-LONDON