Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation

Airway Mucosal Host Defense Is Key to Genomic Regulation of Cystic Fibrosis Lung Disease Severity

(2018) Deepika Polineni et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Functions of Polyamines in Mammals

(2016) Anthony E. Pegg   JOURNAL OF BIOLOGICAL CHEMISTRY

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Change in Pseudomonas aeruginosa prevalence in cystic fibrosis adults over time

(2016) Mathew R. Crull et al.   BMC Pulmonary Medicine

Metabolomic Evaluation of Neutrophilic Airway Inflammation in Cystic Fibrosis

(2015) Charles R. Esther et al.   CHEST

Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell

(2015) Leonor Miller-Fleming et al.   JOURNAL OF MOLECULAR BIOLOGY

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosabiofilm matrix

(2015) Laura K. Jennings et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses

(2015) S. L. LaFayette et al.   Science Advances

Stationary Phase-Specific Virulence Factor Overproduction by a lasR Mutant of Pseudomonas aeruginosa

(2014) Matthew T. Cabeen   PLoS One

The Arginine Decarboxylase Pathways of Host and Pathogen Interact to Impact Inflammatory Pathways in the Lung

(2014) Nick B. Paulson et al.   PLoS One

Agmatine Protects against Zymosan-Induced Acute Lung Injury in Mice by Inhibiting NF-κB-Mediated Inflammatory Response

(2014) Xuanfei Li et al.   Biomed Research International

Agmatine: clinical applications after 100 years in translation

(2013) John E. Piletz et al.   DRUG DISCOVERY TODAY

Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Patients from Two Brazilian Cities

(2013) Larissa Lutz et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Unique microbial communities persist in individual cystic fibrosis patients throughout a clinical exacerbation

(2013) Katherine E Price et al.   Microbiome

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The polymicrobial nature of airway infections in cystic fibrosis: Cangene Gold Medal LectureThis article is based on a presentation by Dr. Christopher Sibley at the 60th Annual Meeting of the Canadian Society of Microbiologists in Hamilton, Ontario, on 15 June 2010. Dr. Sibley was the recipient of the 2010 Cangene Gold Medal as the Canadian Graduate Student Microbiologist of the Year, an annual award sponsored by Cangene Corporation intended to recognize excellence in graduate research.

(2011) Christopher D. Sibley et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Clinical Significance of Microbial Infection and Adaptation in Cystic Fibrosis

(2011) A. R. Hauser et al.   CLINICAL MICROBIOLOGY REVIEWS

Surface-Localized Spermidine Protects the Pseudomonas aeruginosa Outer Membrane from Antibiotic Treatment and Oxidative Stress

(2011) L. Johnson et al.   JOURNAL OF BACTERIOLOGY

Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance

(2010) A. Oliver et al.   CLINICAL MICROBIOLOGY AND INFECTION

Murine models of acute and chronic lung infection with cystic fibrosis pathogens

(2010) Alessandra Bragonzi   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

A Putative ABC Transporter, HatABCDE, Is among Molecular Determinants of Pyomelanin Production in Pseudomonas aeruginosa

(2010) R. C. Hunter et al.   JOURNAL OF BACTERIOLOGY

Discovery of an operon that participates in agmatine metabolism and regulates biofilm formation inPseudomonas aeruginosa

(2010) Bryan J. Williams et al.   MOLECULAR MICROBIOLOGY

Immunoneutralization of Agmatine Sensitizes Mice to  -Opioid Receptor Tolerance

(2009) C. L. Wade et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants

(2009) O. Ciofu et al.   MICROBIOLOGY-SGM

Inactivation of the hmgA gene of Pseudomonas aeruginosa leads to pyomelanin hyperproduction, stress resistance and increased persistence in chronic lung infection

(2009) A. Rodriguez-Rojas et al.   MICROBIOLOGY-SGM

Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression

(2008) Lucas R. Hoffman et al.   Journal of Cystic Fibrosis