Journal
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
Volume 34, Issue 1, Pages 117-123Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14767058.2019.1572737
Keywords
Hepatic dysfunction; hypertension; liver enzymes; pregnancy; proteinuria
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Preeclampsia is a multisystemic disorder with high morbidity and mortality rates among maternal and perinatal populations, especially in middle and low-income countries. Liver biomarkers show potential in predicting the occurrence and outcome of preeclampsia, offering specific predictors for the severe condition resulting from liver dysfunction in the disease.
Preeclampsia is a multisystemic disorder which accounts for the high prevalence of maternal and perinatal morbidity and mortality, especially in middle and low-income countries. Currently, the primary intervention is the urgent delivery of the fetus, hence it would be advantageous to identify those who are likely to develop preeclampsia and the maternal and fetal outcomes. However, an array of risk factors makes these challenging. This review explores the potentials of liver biomarkers in predicting the occurrence and outcome of preeclampsia, which could be beneficial in reducing the burden of the disease. Liver dysfunction in preeclampsia results in a severe condition, hence liver function tests are specific predictors of outcome.
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