Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice
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Title
Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice
Authors
Keywords
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Journal
JOURNAL OF IMMUNOLOGY
Volume 202, Issue 7, Pages 2017-2026
Publisher
The American Association of Immunologists
Online
2019-02-12
DOI
10.4049/jimmunol.1801436
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Note: Only part of the references are listed.- ABT-122, a Bispecific DVD-Immunoglobulin Targeting TNF- and IL-17A, in RA With Inadequate Response to Methotrexate: A Randomized, Double-Blind Study
- (2018) Mark C. Genovese et al. Arthritis & Rheumatology
- Mucocutaneous IL-17 immunity in mice and humans: host defense vs. excessive inflammation
- (2017) J Li et al. Mucosal Immunology
- Immunogenicity and loss of response to TNF inhibitors: implications for rheumatoid arthritis treatment
- (2017) Joachim R. Kalden et al. Nature Reviews Rheumatology
- A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6
- (2017) Remy Robert et al. PLoS One
- IL-17 Signaling: The Yin and the Yang
- (2017) Nilesh Amatya et al. TRENDS IN IMMUNOLOGY
- Safety, Tolerability, and Pharmacodynamics of ABT-122, a Tumor Necrosis Factor- and Interleukin-17-Targeted Dual Variable Domain Immunoglobulin, in Patients With Rheumatoid Arthritis
- (2017) Roy M. Fleischmann et al. Arthritis & Rheumatology
- Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice
- (2017) Manli Na et al. PLoS One
- IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis
- (2016) Heather R. Conti et al. Cell Host & Microbe
- A revolutionary therapeutic approach for psoriasis: bispecific biological agents
- (2016) T. Torres et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Bispecific antibodies
- (2015) Roland E. Kontermann et al. DRUG DISCOVERY TODAY
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- (2015) Heather R. Conti et al. JOURNAL OF IMMUNOLOGY
- IL-23/IL-17A Dysfunction Phenotypes Inform Possible Clinical Effects from Anti-IL-17A Therapies
- (2015) Andrew Blauvelt et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Novel therapeutic targets in rheumatoid arthritis
- (2015) Marije I. Koenders et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Interleukin (IL)-17A, F and AF in inflammation: a study in collagen-induced arthritis and rheumatoid arthritis
- (2014) S. Sarkar et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Treatment with anti-TNF alpha protects against the neuropathy induced by the proteasome inhibitor bortezomib in a mouse model
- (2014) Albert Alé et al. EXPERIMENTAL NEUROLOGY
- Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
- (2014) Richard G. Langley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adaptive Immunity to Fungi
- (2014) A. Verma et al. Cold Spring Harbor Perspectives in Medicine
- Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection
- (2014) Radha Gopal et al. PLoS Pathogens
- Combined Inhibition of Tumor Necrosis Factor α and Interleukin-17 As a Therapeutic Opportunity in Rheumatoid Arthritis: Development and Characterization of a Novel Bispecific Antibody
- (2014) Jens A. A. Fischer et al. Arthritis & Rheumatology
- Opportunistic Infections With Anti-Tumor Necrosis Factor-α Therapy in Inflammatory Bowel Disease: Meta-Analysis of Randomized Controlled Trials
- (2013) Alexander C Ford et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Interleukin-17-Induced Protein Lipocalin 2 Is Dispensable for Immunity to Oral Candidiasis
- (2013) Maria Carolina Ferreira et al. INFECTION AND IMMUNITY
- Endemic Fungal Infections in Inflammatory Bowel Disease Associated with Anti-TNF Antibody Therapy
- (2013) Miguel E. Ordonez et al. INFLAMMATORY BOWEL DISEASES
- Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway
- (2012) Saba Alzabin et al. ANNALS OF THE RHEUMATIC DISEASES
- Effect of IL-17A blockade with secukinumab in autoimmune diseases
- (2012) Dhavalkumar D Patel et al. ANNALS OF THE RHEUMATIC DISEASES
- Anti-TNF treatment blocks the induction of T cell-dependent humoral responses
- (2012) Gabriela Franco Salinas et al. ANNALS OF THE RHEUMATIC DISEASES
- Th17 Cells in Immunity to Candida albicans
- (2012) Nydiaris Hernández-Santos et al. Cell Host & Microbe
- IL-5 and IL-17A are critical for the chronic IgE response and differentiation of long-lived antibody-secreting cells in inflamed tissues
- (2012) Lidiane Zito Grund et al. CYTOKINE
- Mouse model of oropharyngeal candidiasis
- (2012) Norma V Solis et al. Nature Protocols
- Targeting IL-17 and TH17 cells in chronic inflammation
- (2012) Pierre Miossec et al. NATURE REVIEWS DRUG DISCOVERY
- Th17 Effector Cells Support B Cell Responses Outside of Germinal Centres
- (2012) Agapitos Patakas et al. PLoS One
- Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis
- (2011) Marije I. Koenders et al. ARTHRITIS AND RHEUMATISM
- Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance
- (2011) Karin Zwerina et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Functional Specialization of Interleukin-17 Family Members
- (2011) Yoichiro Iwakura et al. IMMUNITY
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- (2011) Marcel Wüthrich et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2011) Thomas Hamilton et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity
- (2011) A. Puel et al. SCIENCE
- Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease
- (2010) Reiko M. Onishi et al. IMMUNOLOGY
- Induction of Neutrophil Gelatinase-associated Lipocalin Expression by Co-stimulation with Interleukin-17 and Tumor Necrosis Factor-α Is Controlled by IκB-ζ but neither by C/EBP-β nor C/EBP-δ
- (2010) Joachim R. Karlsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) F. Shen et al. Science Signaling
- Structure–function relationships in the IL-17 receptor: Implications for signal transduction and therapy
- (2008) Fang Shen et al. CYTOKINE
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