Mutations in the Arabidopsis ROL17/isopropylmalate synthase 1 locus alter amino acid content, modify the TOR network, and suppress the root hair cell development mutant lrx1

Drug discovery targeting the mTOR pathway

(2018) Alberto M. Martelli et al.   CLINICAL SCIENCE

Glucosinolate-Derived Isothiocyanates Inhibit Arabidopsis Growth and the Potency Depends on Their Side Chain Structure

(2017) János Urbancsok et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolomics of laminae and midvein during leaf senescence and source–sink metabolite management in Brassica napus L. leaves

(2017) Gilles Clément et al.   JOURNAL OF EXPERIMENTAL BOTANY

LRX Proteins Play a Crucial Role in Pollen Grain and Pollen Tube Cell Wall Development

(2017) Tohnyui Ndinyanka Fabrice et al.   PLANT PHYSIOLOGY

RALF4/19 peptides interact with LRX proteins to control pollen tube growth inArabidopsis

(2017) Martin A. Mecchia et al.   SCIENCE

The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling

(2017) Martin Stegmann et al.   SCIENCE

An evolutionarily young defense metabolite influences the root growth of plants via the ancient TOR signaling pathway

(2017) Frederikke Gro Malinovsky et al.   eLife

The Regulation of Essential Amino Acid Synthesis and Accumulation in Plants

(2016) Gad Galili et al.   Annual Review of Plant Biology

TOR Signaling and Nutrient Sensing

(2016) Thomas Dobrenel et al.   Annual Review of Plant Biology

The Defense Metabolite, Allyl Glucosinolate, Modulates Arabidopsis thaliana Biomass Dependent upon the Endogenous Glucosinolate Pathway

(2016) Marta Francisco et al.   Frontiers in Plant Science

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6

(2016) Thomas Dobrenel et al.   Frontiers in Plant Science

Arabidopsis leucine-rich repeat extensin (LRX) proteins modify cell wall composition and influence plant growth

(2015) Christian Draeger et al.   BMC PLANT BIOLOGY

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size inArabidopsis thaliana

(2015) Poyu Chen et al.   GENES TO CELLS

Differential regulation of mTORC1 by leucine and glutamine

(2015) J. L. Jewell et al.   SCIENCE

Natural variation in cross-talk between glucosinolates and onset of flowering in Arabidopsis

(2015) Lea M. Jensen et al.   Frontiers in Plant Science

TOR-inhibitor insensitive-1 (TRIN1) regulates cotyledons greening in Arabidopsis

(2015) Linxuan Li et al.   Frontiers in Plant Science

Editorial: Physiology and Cellular Mechanisms of Isothiocyanates and Other Glucosinolate Degradation Products in Plants

(2015) Atle M. Bones et al.   Frontiers in Plant Science

The cytosolic thiouridylase CTU2 of Arabidopsis thaliana is essential for posttranscriptional thiolation of tRNAs and influences root development

(2014) Matthias Philipp et al.   BMC PLANT BIOLOGY

Ubiquitin-Related Modifiers of Arabidopsis thaliana Influence Root Development

(2014) Florian John et al.   PLoS One

A Peptide Hormone and Its Receptor Protein Kinase Regulate Plant Cell Expansion

(2014) M. Haruta et al.   SCIENCE

Abiotic stress-induced accumulation of raffinose in Arabidopsis leaves is mediated by a single raffinose synthase (RS5, At5g40390)

(2013) Aurélie Egert et al.   BMC PLANT BIOLOGY

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation

(2013) Sunil Laxman et al.   CELL

TOR and S6K1 promote translation reinitiation of uORF-containing mRNAs via phosphorylation of eIF3h

(2013) Mikhail Schepetilnikov et al.   EMBO JOURNAL

ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

(2013) Marie-Hélène Montané et al.   JOURNAL OF EXPERIMENTAL BOTANY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Mutations in the Arabidopsis Homolog of LST8/G L, a Partner of the Target of Rapamycin Kinase, Impair Plant Growth, Flowering, and Metabolic Adaptation to Long Days

(2012) M. Moreau et al.   PLANT CELL

Target of Rapamycin Signaling Regulates Metabolism, Growth, and Life Span in Arabidopsis

(2012) M. Ren et al.   PLANT CELL

Systemic analysis of inducible target of rapamycin mutants reveal a general metabolic switch controlling growth inArabidopsis thaliana

(2012) Camila Caldana et al.   PLANT JOURNAL

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Discovery of 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a Potent, Selective, and Orally Available Mammalian Target of Rapamycin (mTOR) Inhibitor for Treatment of Cancer

(2011) Qingsong Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Network Quantitative Trait Loci Mapping of Circadian Clock Outputs Identifies Metabolic Pathway-to-Clock Linkages inArabidopsis

(2011) Rachel E. Kerwin et al.   PLANT CELL

From Amino Acid to Glucosinolate Biosynthesis: Protein Sequence Changes in the Evolution of Methylthioalkylmalate Synthase inArabidopsis

(2011) Jan-Willem de Kraker et al.   PLANT CELL

The PP2A Regulatory Subunit Tap46, a Component of the TOR Signaling Pathway, Modulates Growth and Metabolism in Plants

(2011) Chang Sook Ahn et al.   PLANT CELL

The TOR Pathway Modulates the Structure of Cell Walls inArabidopsis

(2010) Ruth-Maria Leiber et al.   PLANT CELL

Genetic analysis of pathway regulation for enhancing branched-chain amino acid biosynthesis in plants

(2010) Hao Chen et al.   PLANT JOURNAL

Combined Transcript and Metabolite Profiling of Arabidopsis Grown under Widely Variant Growth Conditions Facilitates the Identification of Novel Metabolite-Mediated Regulation of Gene Expression

(2010) M. A. Hannah et al.   PLANT PHYSIOLOGY

TOR Is a Negative Regulator of Autophagy in Arabidopsis thaliana

(2010) Yimo Liu et al.   PLoS One

FERONIA receptor-like kinase regulates RHO GTPase signaling of root hair development

(2010) Qiaohong Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

(2009) C. M. Chresta et al.   CANCER RESEARCH

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA

(2009) Sebastian Leidel et al.   NATURE

Frost tolerance in excised leaves of the common bugle (Ajuga reptansL.) correlates positively with the concentrations of raffinose family oligosaccharides (RFOs)

(2009) SHAUN PETERS et al.   PLANT CELL AND ENVIRONMENT

Unequal functional redundancy between the twoArabidopsis thalianahigh-affinity sulphate transportersSULTR1;1andSULTR1;2

(2008) Marie Barberon et al.   NEW PHYTOLOGIST

The ‘mustard oil bomb’: not so easy to assemble?! Localization, expression and distribution of the components of the myrosinase enzyme system

(2008) Ralph Kissen et al.   PHYTOCHEMISTRY REVIEWS

Quality control for plant metabolomics: reporting MSI-compliant studies

(2008) Oliver Fiehn et al.   PLANT JOURNAL

Amino acid biosynthesis: New architectures in allosteric enzymes

(2008) Gilles Curien et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response

(2008) N. K. Clay et al.   SCIENCE

A Glucosinolate Metabolism Pathway in Living Plant Cells Mediates Broad-Spectrum Antifungal Defense

(2008) P. Bednarek et al.   SCIENCE