Article
Dentistry, Oral Surgery & Medicine
Yueh-Ling Chao, Tong-Mei Wang, Hao-Hueng Chang, Li-Deh Lin
Summary: The study investigated the potential of low-dose rhBMP-2 combined with a composite material in repairing peri-implant critical size defects, with results showing that HAp/TCP/Col +0.2 mg/ml rhBMP-2 demonstrated strong osteogenic potential and improved implant stability.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Hyun-Chang Lim, Kyeong-Won Paeng, Ui-Won Jung, Goran I. Benic
Summary: This study investigated the effects of using bone-block substitute materials with or without recombinant human bone morphogenetic protein-2 (rhBMP-2) on new bone formation. The results showed that rhBMP-2 enhanced new bone formation in all experimental groups, with DBBM blocks resulting in greater new bone area compared to synthetic blocks at 2 weeks. However, there was no significant difference in new bone formation between DBBM and synthetic blocks with rhBMP-2 at 12 weeks.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Basel Mahardawi, Thiha Tin Kyaw, Nikos Mattheos, Atiphan Pimkhaokham
Summary: This systematic review examined the effectiveness of autogenous dentin block grafts for alveolar ridge augmentation. Dentin blocks showed similar vertical bone gain and significantly higher width gain compared to bone blocks. The resorption rates and occurrence of complications were similar between the two groups. Autogenous dentin blocks could be a possible alternative to established bone augmentation techniques, but further studies are needed to confirm its efficacy.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Review
Polymer Science
Manuel Toledano-Osorio, Manuel Toledano, Francisco Javier Manzano-Moreno, Cristina Vallecillo, Marta Vallecillo-Rivas, Alberto Rodriguez-Archilla, Raquel Osorio
Summary: The study concludes that using polymeric membranes for guided bone regeneration (GBR) is an effective technique for achieving horizontal bone augmentation, facilitating proper implant placement.
Article
Dentistry, Oral Surgery & Medicine
Goran Benic, Stefan P. Bienz, Young Woo Song, Jae-Kook Cha, Christoph H. F. Hammerle, Ui-Won Jung, Ronald E. Jung
Summary: This study aimed to compare the efficacy of soft-type block bone substitute and particulate bone substitute in guided bone regeneration of peri-implant defects. The results showed that there was no significant difference in the dimension of the augmented hard tissue between the two materials after 6 months of healing.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Deng-Hui Duan, Hom-Lay Wang, Wu-Cai Xiao, Zheng Liu, En-Bo Wang
Summary: In the short-term, titanium plate-enhanced GBR maintained ridge dimensions better than conventional GBR did.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2022)
Review
Dentistry, Oral Surgery & Medicine
B. Mahardawi, S. Jiaranuchart, K. A. Tompkins, A. Pimkhaokham
Summary: The aim of this study was to compare the clinical performance of autogenous dentin graft (ADG) with other bone graft materials for implant placement. Nine articles were included in the meta-analysis, which showed that ADG had similar primary and secondary implant stability to Bio-Oss. The marginal bone loss, survival rate, and incidence of complications were also comparable between ADG and Bio-Oss. This study demonstrates that ADG is an effective option for bone augmentation around dental implants.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Stefan Fickl, Annika Therese Kroger, Thomas Dietrich, Moritz Kebschull
Summary: This systematic review found that soft tissue augmentation procedures inconsistently affected marginal bone level changes, but consistently improved secondary outcomes. The combination of soft and hard tissue augmentation showed better results in terms of marginal soft tissue recession compared to hard tissue augmentation alone. Contour augmentations with soft or hard tissue augmentation resulted in comparable marginal bone level changes.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Hanna Aludden, Arne Mordenfeld, Andreas Cederlund, Christer Dahlin, Rubens Spin-Neto, Pernille Veiss-Pedersen, Babyasha Sritharan, Thomas Starch-Jensen
Summary: The study aimed to evaluate the effects of different ratios of DBBM and PAB, along with ABB, on bone augmentation height and volume after lateral GBR surgery. Results showed that after 30 weeks, ABB preserved augmentation height better compared to other ratios, while there was no significant difference in volumetric reduction between ABB and all particulate grafts.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Eun-Hee Jung, Seong-Nyum Jeong, Jae-Hong Lee
Summary: The study found that L- and I-shaped DBBM-C were more beneficial in terms of horizontal augmentation stability compared to DBBM after a 5-month healing period in peri-implant dehiscence defects. Early postoperative discomfort, wound healing outcomes, and periotest values did not differ significantly between the different groups.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Shih-Cheng Wen, Shayan Barootchi, Hom-Lay Wang, Wen-Xia Huang
Summary: This study investigated a non-submerged reconstructive approach for peri-implantitis osseous defects, which showed significant improvements in clinical and radiographic outcomes.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Pier Gallo, David Diaz-Baez, Sandra Perdomo, Antonio Carlos Aloise, Mustafa Tattan, Muhammad H. A. Saleh, Andre Antonio Pelegrine, Andrea Ravida, Hom-Lay Wang
Summary: This study aimed to assess vital mineralized tissue formation in vertical ridge augmentation procedures using autogenous bone chips mixed with either an allograft or a xenograft.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2022)
Review
Dentistry, Oral Surgery & Medicine
B. Mahardawi, S. Rochanavibhata, S. Jiaranuchart, S. Arunjaroensuk, N. Mattheos, A. Pimkhaokham
Summary: This systematic review evaluates the clinical outcomes and current applications of autogenous tooth bone graft in patients. The results indicate that the use of this graft leads to increased bone volume and high implant survival rates. However, current studies have limitations such as small sample sizes, short follow-up periods, and lack of control groups.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Sirida Arunjaroensuk, Pasutha Thunyakitpisal, Katanchalee Nampuksa, Naruporn Monmaturapoj, Nikos Mattheos, Atiphan Pimkhaokham
Summary: The aim of this study was to compare the stability of augmented bone using different ratios of biphasic calcium phosphate (BCP) with hydroxyapatite/beta-tricalcium phosphate. The results showed that the 70/30 BCP ratio was significantly better in maintaining facial thickness and stability of horizontal dimensions of the augmented site compared to the 60/40 BCP ratio. BCP grafts with both ratios showed comparable outcomes for contour augmentation simultaneously with implant placement.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Thomas Starch-Jensen, Soren Schou, Hendrik Terheyden, Niels Henrik Bruun, Hanna Aludden
Summary: This study tested the hypothesis of no difference in bone regeneration after maxillary sinus floor augmentation using different ratios of iliac or mandibular autograft and deproteinized bovine bone mineral. The results showed that the percentage of bone regeneration significantly increased with a higher ratio of autograft, regardless of the origin of the graft.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Review
Dentistry, Oral Surgery & Medicine
Gustavo Avila-Ortiz, Emilio Couso-Queiruga, Miha Pirc, Leandro Chambrone, Daniel S. Thoma
Summary: This study aims to identify and report outcome measures and assessment methods for soft tissue augmentation interventions in dental implant therapy. The results show that clinical outcome measures are the most frequently reported, with a trend towards the use of digital technologies. Patient-reported outcome measures are often under-reported but should be considered important in future research.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Gustavo Avila-Ortiz, Emilio Couso-Queiruga, Miha Pirc, Leandro Chambrone, Daniel S. Thoma
Summary: The aim of this study was to identify and report outcome measures and assessment methods for soft-tissue augmentation interventions in dental implant therapy in the last 10 years. The analysis showed that clinical outcomes were the most commonly reported outcomes, and there was a trend towards the use of digital technologies. Patient-reported outcome measures were generally underreported but should be considered in future clinical studies.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anina N. Zuercher, Alexis Ioannidis, Jurg Husler, Albert Mehl, Christoph H. F. Hammerle, Daniel S. Thoma
Summary: This study aimed to compare the performance of a chairside workflow and a labside workflow in terms of efficacy and efficiency. The results showed that the two workflows had similar scores in patient satisfaction evaluation, while there was a moderate negative correlation in the objective evaluation by clinicians. Therefore, patient satisfaction plays a significant role in the decision-making process for single-tooth restorations.
JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Daniel S. Thoma, Thomas J. W. Gasser, Christoph H. F. Haemmerle, Franz J. Strauss, Ronald E. Jung
Summary: This randomized controlled trial aimed to assess the long-term clinical and radiographic outcomes of soft tissue augmentation using volume-stable collagen matrix (VCMX) or subepithelial connective tissue grafts (SCTGs) at implant sites. The study found that both VCMX and SCTG resulted in stable peri-implant tissues, favorable esthetics, and clinically negligible contour changes at 5 years post loading.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Daniel S. Thoma, Franz J. Strauss, Leonardo Mancini, Thomas J. W. Gasser, Ronald E. Jung
Summary: The aim of this study was to compare patient-reported outcome measures of soft tissue substitutes versus autogenous grafts for soft tissue augmentation procedures at implant sites. The results showed that soft tissue substitutes significantly improved pain perception, reduced painkiller usage, and shortened surgery time compared to autogenous grafts.
PERIODONTOLOGY 2000
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anina-Nives Zuercher, Leonardo Mancini, Nadja Naenni, Daniel-Stefan Thoma, Franz-Josef Strauss, Ronald-Ernst Jung
Summary: This study describes the L-shape technique in guided bone regeneration (GBR) with simultaneous implant placement and reports on its clinical, esthetic, and patient satisfaction outcomes up to 14 years of follow-up. The results show that the L-shape augmentation procedure is a reliable technique for GBR and simultaneous implant placement in the esthetic zone, with stable clinical and esthetic results and high levels of patient satisfaction.
JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Leonardo Mancini, Shayan Barootchi, Daniel S. Thoma, Ronald E. Jung, German O. Gallucci, Hom-Lay Wang, Lorenzo Tavelli
Summary: This study describes the methods for assessing and reporting the color of peri-implant mucosa (PMC) and emphasizes its impact on the esthetic outcome of implant therapy. A total of 121 clinical studies were included, which reported on various methods of PMC assessment including qualitative and quantitative methods. The assessment allowed for the description of color discrepancies, evaluation of color changes over time, and comparison of treatment outcomes.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
David Martin-Hernandez, Maria Martinez, Javier Robledo-Montana, Marina Munoz-Lopez, Leire Virto, Nagore Ambrosio, Maria Jose Marin, Eduardo Montero, David Herrera, Mariano Sanz, Juan C. Leza, Elena Figuero, Borja Garcia-Bueno
Summary: This study investigated the potential mechanisms underlying the association between periodontitis and depression. Using a rat model, the study found that neuroinflammation (microglia, blood-brain barrier permeability, and sphingosine-1-phosphate pathways) may play a role in this association. The findings showed that the combined effects of periodontitis and chronic mild stress increased neuroinflammation and disrupted the blood-brain barrier. The study also identified differential regulation of enzymes and receptors in the sphingosine-1-phosphate pathway. These findings contribute to our understanding of the relationship between periodontitis and depression.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Viviane Laura Humm, Irena Sailer, Daniel Stefan Thoma, Christoph Hans Franz Hammerle, Ronald Ernst Jung, Anja Zembic
Summary: This study assessed the survival rates and compared the outcomes of customized zirconia and titanium abutments at 13 years post loading. The results showed that using both zirconia and titanium abutments for single implant-borne restorations had high survival rates and minimal differences in terms of technical, biological, and esthetic outcomes.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Maurizio S. Tonetti, Mariano Sanz, Gustavo Avila-Ortiz, Tord Berglundh, Francesco Cairo, Jan Derks, Elena Figuero, Filippo Graziani, Fernando Guerra, Lisa Heitz-Mayfield, Ronald E. Jung, Hongchang Lai, Ian Needleman, Panos N. Papapanou, Irena Sailer, Ignacio Sanz-Sanchez, Frank Schwarz, Junyu Shi, Daniel Thoma
Summary: To improve evidence-based implant dentistry and quality of care, this study aimed to develop a core outcome set and measurements for implant dentistry clinical trials. Through systematic reviews, patient focus groups, and expert discussions, 13 mandatory outcome domains were identified, including pathophysiology, implant/prosthesis lifespan, life impact, and access to care. These domains captured both the benefits and harms of therapy and will contribute to improving evidence-informed implant dentistry and quality of care.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Stefan P. P. Bienz, Edwin Ruales Carrera, Jurg Husler, Andrea Roccuzzo, Ronald E. E. Jung, Daniel S. S. Thoma
Summary: The objective of this study was to evaluate the volumetric changes and peri-implant health at implant sites with and without previous soft tissue grafting over a 12-year observation period. The results showed no significant differences between the implant sites with and without soft tissue grafting in terms of volumetric changes and peri-implant health over the 12-year period.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
David Herrera, Tord Berglundh, Frank Schwarz, Iain Chapple, Soren Jepsen, Anton Sculean, Moritz Kebschull, Panos N. Papapanou, Maurizio S. Tonetti, Mariano Sanz
Summary: This study aims to develop clinical practice guidelines for the prevention and treatment of peri-implant diseases, emphasizing the need for interdisciplinary approaches and interventions at different stages. The guidelines provide recommendations for maintaining healthy peri-implant tissues and managing peri-implant diseases.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Leonardo Mancini, Daniel S. S. Thoma, Enrico Marchetti, Jung Ronald Ernst, Franz J. J. Strauss
Summary: This study describes a novel 3D method for estimating the emergence profile and restorative angles of single implant-supported crowns, including the buccal sites. The crowns were scanned using an intraoral scanner and analyzed using 3D software. The results show that this 3D analysis method is reliable and applicable in daily practice.
JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
A. N. Zuercher, F. J. Strauss, P. N. Paque, S. P. Bienz, R. E. Jung, D. S. Thoma
Summary: This study compared the effectiveness of subepithelial connective tissue grafts (SCTG) and guided bone regeneration (GBR) in treating small peri-implant dehiscence defects. The results showed that SCTG may be a viable alternative to GBR, as it resulted in more stable profilometric outcomes and comparable clinical outcomes.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Stefan P. Bienz, Cedryck Vaquette, Alexis Ioannidis, Christoph H. F. Haemmerle, Ronald E. Jung, Saso Ivanovski, Daniel S. Thoma
Summary: This study analyzed the influence of compression on tissue integration and degradation of soft tissue substitutes. The results showed that higher levels of compression led to delayed tissue integration. The effect of different compression levels was more significant compared to the differences between the materials.
CLINICAL ORAL INVESTIGATIONS
(2023)