Comparative Study between Revitalization of Necrotic Immature Permanent Anterior Teeth with and without Platelet Rich Fibrin: A Randomized Controlled Trial

Objectives: This study was conducted to evaluate the effect of platelet rich fibrin (PRF) during revitalization of necrotic immature permanent anterior teeth after 6 months and 1 year follow up period. The following treatment protocols; Group A: revitalization using blood clot scaffold only, and Group B: revitalization using blood clot and PRF. Study design: twenty-two patients (7-12 years old) suffering from immature necrotic permanent maxillary central incisors were randomly selected and randomly allocated into 2 groups. Clinical examinations were performed to detect any pain or swelling during the follow up period. Standardized radiographs were digitally evaluated for changes in root length, periapical radiolucency size, presence of apical or cervical calcific bridges. Results: After a follow-up period of 12 months, most of the cases showed radiographic evidence of periapical healing and showed calcific bridges either cervical and /or apical. No significant differences were shown between both groups. Conclusions: The revitalization procedures succeeded to show continued development of roots in teeth with necrotic pulps. The use of PRF was not essential for repair but it helped during the procedures.