CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia

(2018) Miriam Y. Kim et al.   CELL

Tissue-Specific Expression of the Low-Affinity IgG Receptor, FcγRIIb, on Human Mast Cells

(2018) Oliver T. Burton et al.   Frontiers in Immunology

Half-life of IgE in serum and skin: Consequences for anti-IgE therapy in patients with allergic disease

(2017) Monica G. Lawrence et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ibrutinib, a Bruton’s tyrosine kinase inhibitor used for treatment of lymphoproliferative disorders, eliminates both aeroallergen skin test and basophil activation test reactivity

(2017) Jennifer A. Regan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2

(2017) Kelly A. Orgel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Omalizumab facilitates rapid oral desensitization for peanut allergy

(2017) Andrew J. MacGinnitie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model

(2017) Kyle J. Bednar et al.   JOURNAL OF IMMUNOLOGY

Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices

(2016) Cynthia J Koziol-White et al.   BRITISH JOURNAL OF PHARMACOLOGY

Food allergen immunotherapy: Current status and prospects for the future

(2016) Robert A. Wood   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The future of biologics: Applications for food allergy

(2015) Rebecca N. Bauer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Biology and Disease Relevance of CD300a, an Inhibitory Receptor for Phosphatidylserine and Phosphatidylethanolamine

(2015) Olatz Zenarruzabeitia et al.   JOURNAL OF IMMUNOLOGY

The past and future of CD33 as therapeutic target in acute myeloid leukemia

(2014) George S. Laszlo et al.   BLOOD REVIEWS

Immunoglobulin E Signal Inhibition during Allergen Ingestion Leads to Reversal of Established Food Allergy and Induction of Regulatory T Cells

(2014) Oliver T. Burton et al.   IMMUNITY

Siglec-7 is an inhibitory receptor on human mast cells and basophils

(2014) Sa'ar Mizrahi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular targets on mast cells and basophils for novel therapies

(2014) Ilkka T. Harvima et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas

(2014) Cory D. Rillahan et al.   Chemical Science

Allergic diseases and asthma: a global public health concern and a call to action

(2014) Ruby Pawankar   World Allergy Organization Journal

Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells

(2013) Tatsuya Oka et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Anaphylaxis in America: The prevalence and characteristics of anaphylaxis in the United States

(2013) Robert A. Wood et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis

(2013) Matthew S. Macauley et al.   JOURNAL OF CLINICAL INVESTIGATION

Copresentation of Antigen and Ligands of Siglec-G Induces B Cell Tolerance Independent of CD22

(2013) F. Pfrengle et al.   JOURNAL OF IMMUNOLOGY

Blockade of peanut allergy with a novel Ara h 2–Fcγ fusion protein in mice

(2012) Yu Liu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgE and mast cells in allergic disease

(2012) Stephen J Galli et al.   NATURE MEDICINE

Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein

(2011) A. Eggel et al.   ALLERGY

Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of Haptens

(2011) Anne Dudeck et al.   IMMUNITY

Current Understanding of Egg Allergy

(2011) Jean-Christoph Caubet et al.   PEDIATRIC CLINICS OF NORTH AMERICA

The Prevalence, Severity, and Distribution of Childhood Food Allergy in the United States

(2011) R. S. Gupta et al.   PEDIATRICS

Clinical immunology review series: an approach to desensitization

(2010) M. T. Krishna et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Signal Peptide of the IgE Receptor α-Chain Prevents Surface Expression of an Immunoreceptor Tyrosine-based Activation Motif-free Receptor Pool

(2010) Barbara Platzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine B Cells Regulate Serum IgE Levels in a CD23-Dependent Manner

(2010) L. E. Cheng et al.   JOURNAL OF IMMUNOLOGY

An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E–mediated immediate hypersensitivity reactions

(2010) Kaori Hitomi et al.   NATURE IMMUNOLOGY

A Minor Catalytic Activity of Src Family Kinases Is Sufficient for Maximal Activation of Mast Cells via the High-Affinity IgE Receptor

(2009) Michael Poderycki et al.   JOURNAL OF IMMUNOLOGY

New developments in mast cell biology

(2008) Janet Kalesnikoff et al.   NATURE IMMUNOLOGY

Inhibition of FcεRI-dependent mediator release and calcium flux from human mast cells by sialic acid–binding immunoglobulin-like lectin 8 engagement

(2007) Hidenori Yokoi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY