Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

(2018) Susan W. Robinson et al.   PLOS BIOLOGY

Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous Neurotransmission

(2016) Nadezhda Sabeva et al.   JOURNAL OF NEUROSCIENCE

Functional Roles of Complexin 3 and Complexin 4 at Mouse Photoreceptor Ribbon Synapses

(2016) Norbert Babai et al.   JOURNAL OF NEUROSCIENCE

Should I stop or should I go? The role of complexin in neurotransmitter release

(2016) Thorsten Trimbuch et al.   NATURE REVIEWS NEUROSCIENCE

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

(2016) Shan Shan H. Wang et al.   NEURON

C-terminal domain of mammalian complexin-1 localizes to highly curved membranes

(2016) Jihong Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses

(2016) Lena S. Mortensen et al.   Cell Reports

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

Imaging Exocytosis of Single Synaptic Vesicles at a Fast CNS Presynaptic Terminal

(2015) Mitsuharu Midorikawa et al.   NEURON

Merits and Limitations of Vesicle Pool Models in View of Heterogeneous Populations of Synaptic Vesicles

(2015) Erwin Neher   NEURON

Molecular Underpinnings of Synaptic Vesicle Pool Heterogeneity

(2015) Devon C. Crawford et al.   TRAFFIC

Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation

(2015) Mila M. Paul et al.   Frontiers in Cellular Neuroscience

Miniature Neurotransmission Regulates Drosophila Synaptic Structural Maturation

(2014) Ben Jiwon Choi et al.   NEURON

The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones

(2014) Cordelia Imig et al.   NEURON

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states

(2014) Nadine Ehmann et al.   Nature Communications

HDAC6 Is a Bruchpilot Deacetylase that Facilitates Neurotransmitter Release

(2014) Katarzyna Miskiewicz et al.   Cell Reports

Methylene Blue- and Thiol-Based Oxygen Depletion for Super-Resolution Imaging

(2013) Philip Schäfer et al.   ANALYTICAL CHEMISTRY

Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release

(2013) Pascal S. Kaeser et al.   Annual Review of Physiology

Cryo–electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering

(2013) Rubén Fernández-Busnadiego et al.   JOURNAL OF CELL BIOLOGY

Spontaneous and Evoked Release Are Independently Regulated at Individual Active Zones

(2013) J. E. Melom et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms of COMPLEXIN fusion clamp function in synaptic exocytosis revealed in a new Drosophila mutant

(2013) Janani Iyer et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Synaptic Vesicles Position Complexin to Block Spontaneous Fusion

(2013) Rachel T. Wragg et al.   NEURON

Hebbian Plasticity Guides Maturation of Glutamate Receptor Fields In Vivo

(2013) Dmitrij Ljaschenko et al.   Cell Reports

Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin

(2012) Lauren K. Buhl et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

rapidSTORM: accurate, fast open-source software for localization microscopy

(2012) Steve Wolter et al.   NATURE METHODS

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Sustaining rapid vesicular release at active zones: potential roles for vesicle tethering

(2012) Stefan Hallermann et al.   TRENDS IN NEUROSCIENCES

Complexin Maintains Vesicles in the Primed State in C. elegans

(2011) Robert J. Hobson et al.   CURRENT BIOLOGY

Complexin Has Opposite Effects on Two Modes of Synaptic Vesicle Fusion

(2011) Jesse A. Martin et al.   CURRENT BIOLOGY

Rapid Active Zone Remodeling during Synaptic Plasticity

(2011) A. Weyhersmuller et al.   JOURNAL OF NEUROSCIENCE

Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming

(2011) Josefin Snellman et al.   NATURE NEUROSCIENCE

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

(2011) Sebastian van de Linde et al.   Nature Protocols

The reserve pool of synaptic vesicles acts as a buffer for proteins involved in synaptic vesicle recycling

(2011) A. Denker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of short‐term plasticity at neuromuscular active zones of Drosophila

(2010) Stefan Hallermann et al.   HFSP Journal

Naked Dense Bodies Provoke Depression

(2010) S. Hallermann et al.   JOURNAL OF NEUROSCIENCE

Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release

(2010) Richard W. Cho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Complexin: Does It Deserve Its Name?

(2010) Erwin Neher   NEURON

Bassoon and the Synaptic Ribbon Organize Ca2+ Channels and Vesicles to Add Release Sites and Promote Refilling

(2010) Thomas Frank et al.   NEURON

Bassoon Speeds Vesicle Reloading at a Central Excitatory Synapse

(2010) Stefan Hallermann et al.   NEURON

Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila

(2009) Subhabrata Sanyal   GENE EXPRESSION PATTERNS

Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4

(2009) K. Reim et al.   JOURNAL OF CELL SCIENCE

Real-time computation of subdiffraction-resolution fluorescence images

(2009) S. WOLTER et al.   JOURNAL OF MICROSCOPY

Tilting the Balance between Facilitatory and Inhibitory Functions of Mammalian and Drosophila Complexins Orchestrates Synaptic Vesicle Exocytosis

(2009) Mingshan Xue et al.   NEURON

Calcium Dependence of Exo- and Endocytotic Coupling at a Glutamatergic Synapse

(2009) Nobutake Hosoi et al.   NEURON

Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes

(2008) Mike Heilemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three-Dimensional Resolution Doubling in Wide-Field Fluorescence Microscopy by Structured Illumination

(2008) Mats G.L. Gustafsson et al.   BIOPHYSICAL JOURNAL

Visualizing glutamatergic cell bodies and synapses inDrosophila larval and adult CNS

(2008) Richard W. Daniels et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes

(2008) Michele Markstein et al.   NATURE GENETICS

Highly inclined thin illumination enables clear single-molecule imaging in cells

(2008) Makio Tokunaga et al.   NATURE METHODS

Activity-dependent site-specific changes of glutamate receptor composition in vivo

(2008) Andreas Schmid et al.   NATURE NEUROSCIENCE

For Better or for Worse: Complexins Regulate SNARE Function and Vesicle Fusion

(2008) Nils Brose   TRAFFIC