Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER–mitochondria contacts

Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER

(2018) Jonathan R. Friedman et al.   DEVELOPMENTAL CELL

Budding Yeast Has a Minimal Endomembrane System

(2018) Kasey J. Day et al.   DEVELOPMENTAL CELL

Coenzyme Q 10 deficiencies: pathways in yeast and humans

(2018) Agape M. Awad et al.   Essays in Biochemistry

The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation

(2018) Lee J. Sweetlove et al.   Nature Communications

Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis

(2018) Christopher P. Lapointe et al.   Cell Systems

Identification of a multienzyme complex for glucose metabolism in living cells

(2017) Casey L. Kohnhorst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The glycolytic enzyme phosphofructokinase-1 assembles into filaments

(2017) Bradley A. Webb et al.   JOURNAL OF CELL BIOLOGY

A New View into the Regulation of Purine Metabolism: The Purinosome

(2017) Anthony M. Pedley et al.   TRENDS IN BIOCHEMICAL SCIENCES

Biochemistry of Mitochondrial Coenzyme Q Biosynthesis

(2017) Jonathan A. Stefely et al.   TRENDS IN BIOCHEMICAL SCIENCES

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

(2017) Inge Kühl et al.   eLife

Coenzyme Q biosynthesis in health and disease

(2016) Manuel Jesús Acosta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization

(2016) Juan B. Rodríguez-Molina et al.   MOLECULAR CELL

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

(2016) Brendan J. Floyd et al.   MOLECULAR CELL

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity

(2016) Jonathan A. Stefely et al.   MOLECULAR CELL

Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

(2016) Jonathan A Stefely et al.   NATURE BIOTECHNOLOGY

Spatial colocalization and functional link of purinosomes with mitochondria

(2016) J. B. French et al.   SCIENCE

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

(2016) Samantha C. Lewis et al.   SCIENCE

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure and function of mitochondrial membrane protein complexes

(2015) Werner Kühlbrandt   BMC BIOLOGY

The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene

(2015) M. Luna-Sanchez et al.   EMBO Molecular Medicine

Coq6 Is Responsible for the C4-deamination Reaction in Coenzyme Q Biosynthesis inSaccharomyces cerevisiae

(2015) Mohammad Ozeir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Coq11, a New Coenzyme Q Biosynthetic Protein in the CoQ-Synthome inSaccharomyces cerevisiae

(2015) Christopher M. Allan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

(2015) Andrew Murley et al.   JOURNAL OF CELL BIOLOGY

ER–mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13

(2015) Alexander B. Lang et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis

(2015) Jonathan A. Stefely et al.   MOLECULAR CELL

A general method to improve fluorophores for live-cell and single-molecule microscopy

(2015) Jonathan B Grimm et al.   NATURE METHODS

Purinosome formation as a function of the cell cycle

(2015) Chung Yu Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lam6 Regulates the Extent of Contacts between Organelles

(2015) Yael Elbaz-Alon et al.   Cell Reports

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants

(2014) Cuiwen H. He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis

(2014) D. C. Lohman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial ATP synthases cluster as discrete domains that reorganize with the cellular demand for oxidative phosphorylation

(2013) Laure Jimenez et al.   JOURNAL OF CELL SCIENCE

Coenzyme Q10 deficiency in mitochondrial DNA depletion syndromes

(2013) Raquel Montero et al.   MITOCHONDRION

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

(2013) Andrew Murley et al.   eLife

Overexpression of the Coq8 Kinase inSaccharomyces cerevisiae coqNull Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q6Biosynthetic Pathway

(2012) Letian X. Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coenzyme Q Biosynthesis: Coq6 Is Required for the C5-Hydroxylation Reaction and Substrate Analogs Rescue Coq6 Deficiency

(2011) Mohammad Ozeir et al.   CHEMISTRY & BIOLOGY

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

Bacteria, yeast, worms, and flies: Exploiting simple model organisms to investigate human mitochondrial diseases

(2010) Shane L. Rea et al.   Developmental Disabilities Research Reviews

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

Identification of a novel conserved sequence motif in flavoprotein hydroxylases with a putative dual function in FAD/NAD(P)H binding

(2009) Michel H. M. Eppink et al.   PROTEIN SCIENCE

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis

(2008) Beth Marbois et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS