Efficient route to RIKEN click probes for glycoconjugation

A viable strategy for screening the effects of glycan heterogeneity on target organ adhesion and biodistribution in live mice

(2018) Akihiro Ogura et al.   CHEMICAL COMMUNICATIONS

Highly reactive “RIKEN click” probe for glycoconjugation on lysines

(2017) Regina Sibgatullina et al.   TETRAHEDRON LETTERS

A One-Pot Three-Component Double-Click Method for Synthesis of [67Cu]-Labeled Biomolecular Radiotherapeutics

(2017) Katsumasa Fujiki et al.   Scientific Reports

Glycan multivalency effects toward albumin enable N-glycan-dependent tumor targeting

(2016) Akihiro Ogura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemically synthesized glycoconjugates on proteins: effects of multivalency and glycoform in vivo

(2016) Katsunori Tanaka   ORGANIC & BIOMOLECULAR CHEMISTRY

Sequential Double “Clicks” toward Structurally Well-Defined Heterogeneous N -Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo

(2016) Liliya Latypova et al.   Advanced Science

Visualizing Trimming Dependence of Biodistribution and Kinetics with Homo- and Heterogeneous N-Glycoclusters on Fluorescent Albumin

(2016) Akihiro Ogura et al.   Scientific Reports

Site-selective protein-modification chemistry for basic biology and drug development

(2015) Nikolaus Krall et al.   Nature Chemistry

Scalable Synthesis of Strained Cyclooctyne Derivatives

(2014) Alex Adronov et al.   SYNTHESIS-STUTTGART

Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms

(2011) Roberto C. Davicino et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Exploring a Unique Reactivity of 6π-Azaelectrocyclization to Enzyme Inhibition, Natural Products Synthesis, and Molecular Imaging: An Approach to Chemical Biology by Synthetic Chemists

(2011) Katsunori Tanaka et al.   SYNLETT

Noninvasive Imaging of Dendrimer-Type N-Glycan Clusters: In Vivo Dynamics Dependence on Oligosaccharide Structure

(2010) Katsunori Tanaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lectins as pattern recognition molecules: The effects of epitope density in innate immunity

(2009) T. K Dam et al.   GLYCOBIOLOGY

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PET (positron emission tomography) imaging of biomolecules using metal–DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics

(2008) Katsunori Tanaka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Submicrogram-Scale Protocol for Biomolecule-Based PET Imaging by Rapid 6π-Azaelectrocyclization: Visualization of Sialic Acid Dependent Circulatory Residence of Glycoproteins

(2007) Katsunori Tanaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION