Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved

New application of the commercial sweetener rebaudioside a as a hepatoprotective candidate: Induction of the Nrf2 signaling pathway

(2018) Yuxin Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation

(2018) Erika Ramos-Tovar et al.   Oxidative Medicine and Cellular Longevity

Antioxidant and anti-inflammatory activities of berberine attenuate hepatic fibrosis induced by thioacetamide injection in rats

(2018) Laila Ahmed Eissa et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Stevia rebaudiana tea prevents experimental cirrhosis via regulation of NF-κB, Nrf2, transforming growth factor beta, Smad7, and hepatic stellate cell activation

(2018) Erika Ramos-Tovar et al.   PHYTOTHERAPY RESEARCH

Stevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation

(2018) Sael Casas-Grajales et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Stevia and stevioside protect against cisplatin nephrotoxicity through inhibition of ERK1/2, STAT3, and NF-κB activation

(2017) Iva Potočnjak et al.   FOOD AND CHEMICAL TOXICOLOGY

PDGF signaling pathway in hepatic fibrosis pathogenesis and therapeutics

(2017) Hua-Zhong Ying et al.   Molecular Medicine Reports

Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways

(2017) Erika Hernández-Aquino et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution

(2016) Andrea Baiocchini et al.   PLoS One

Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: A transcriptomic and metabolomic study

(2015) Paul Holvoet et al.   FOOD AND CHEMICAL TOXICOLOGY

The Role of Oxidative Stress and Antioxidants in Liver Diseases

(2015) Sha Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Matrix metalloproteinases in liver injury, repair and fibrosis

(2015) Sergio Duarte et al.   MATRIX BIOLOGY

Emerging and Disease-Specific Mechanisms of Hepatic Stellate Cell Activation

(2015) Michael Wallace et al.   SEMINARS IN LIVER DISEASE

The non-cytotoxicity characterization of rebaudioside A as a food additive

(2014) Xiaoli Wu et al.   FOOD AND CHEMICAL TOXICOLOGY

Modulating efficacy of Rebaudioside A, a diterpenoid on antioxidant and circulatory lipids in experimental diabetic rats

(2013) Ramalingam Saravanan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Anti-inflammatory and immunomodulatory activities of stevioside and steviol on colonic epithelial cells

(2013) Chaiwat Boonkaewwan et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Stevioside Suppressed Inflammatory Cytokine Secretion by Downregulation of NF-κB and MAPK Signaling Pathways in LPS-Stimulated RAW264.7 Cells

(2012) Li Fengyang et al.   INFLAMMATION

Thymosin-β4 (Tβ4) Blunts PDGF-Dependent Phosphorylation and Binding of AKT to Actin in Hepatic Stellate Cells

(2011) Karina Reyes-Gordillo et al.   AMERICAN JOURNAL OF PATHOLOGY

Smad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells

(2011) Koichi Matsuzaki   CELL AND TISSUE RESEARCH

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Human primary cultured hepatic stellate cells can be cryopreserved

(2010) Anna Nakamura et al.   Medical Molecular Morphology

Rebaudioside A: Two-generation reproductive toxicity study in rats

(2008) Leslie L. Curry et al.   FOOD AND CHEMICAL TOXICOLOGY

Chronic consumption of rebaudioside A, a steviol glycoside, in men and women with type 2 diabetes mellitus

(2008) K.C. Maki et al.   FOOD AND CHEMICAL TOXICOLOGY

Subchronic toxicity of rebaudioside A

(2008) Leslie L. Curry et al.   FOOD AND CHEMICAL TOXICOLOGY

The hemodynamic effects of rebaudioside A in healthy adults with normal and low-normal blood pressure

(2008) K.C. Maki et al.   FOOD AND CHEMICAL TOXICOLOGY

A 90-Day Oral (Dietary) Toxicity Study of Rebaudioside A in Sprague-Dawley Rats

(2008) Andrey I Nikiforov et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY